Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes

European Journal of Pharmacology

Volumn 776, Issue , 2016, Pages 167-175

  Tokarz, Paulina ^a   Kaarniranta, Kai ^b,c   Blasiak, Janusz ^a  

^a UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

ARPE 19; DNA damage response; Epigenetic inhibitors; Oxidative stress; Reactive oxygen species

Indexed keywords

CATALASE; DNA METHYLTRANSFERASE; GLUCOSE OXIDASE; GLUTATHIONE PEROXIDASE; HISTONE DEACETYLASE; N PHTHALOYLTRYPTOPHAN; SUPEROXIDE DISMUTASE; VALPROIC ACID; ANTIOXIDANT; DNA (CYTOSINE 5) METHYLTRANSFERASE; HISTONE DEACETYLASE INHIBITOR; PHTHALIMIDE DERIVATIVE; REACTIVE OXYGEN METABOLITE; TRYPTOPHAN;

ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ELECTROPHORESIS; ENZYME ACTIVATION; ENZYME INHIBITION; EPIGENETICS; EXCISION REPAIR; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MELTING POINT; OXIDATIVE STRESS; PHOTORECEPTOR; PRIORITY JOURNAL; PROMOTER REGION; UPREGULATION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DNA REPAIR; DRUG EFFECTS; ENZYMOLOGY; G2 PHASE CELL CYCLE CHECKPOINT; M PHASE CELL CYCLE CHECKPOINT; METABOLISM; RETINAL PIGMENT EPITHELIUM; TIME FACTOR;

ANTIOXIDANTS; CELL LINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA DAMAGE; DNA REPAIR; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; OXIDATIVE STRESS; PHTHALIMIDES; REACTIVE OXYGEN SPECIES; RETINAL PIGMENT EPITHELIUM; TIME FACTORS; TRYPTOPHAN; VALPROIC ACID;

EID: 84960877584     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.02.049     Document Type: Article

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