IgE epitope proximity determines immune complex shape and effector cell activation capacity

Journal of Allergy and Clinical Immunology

Volumn 137, Issue 5, 2016, Pages 1557-1565

  Gieras, Anna ^a   Linhart, Birgit ^a   Roux, Kenneth H ^b   Dutta, Moumita ^b   Khodoun, Marat ^c,d,e   Zafred, Domen ^f   Cabauatan, Clarissa R ^a   Lupinek, Christian ^a   Weber, Milena ^a   Focke Tejkl, Margarete ^a   Keller, Walter ^f   Finkelman, Fred D ^c,d,e   Valenta, Rudolf ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b FLORIDA STATE UNIVERSITY   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^e CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^f UNIVERSITY OF GRAZ   (Austria)

Author keywords

allergen; Allergy; effector cells; IgE epitope; immune complex

Indexed keywords

EPITOPE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; RECOMBINANT ALLERGEN; SCAFFOLD PROTEIN; ALLERGEN; ANTIGEN ANTIBODY COMPLEX; MYOGLOBIN; PHLPI PROTEIN, PHLEUM PRATENSE; PLANT PROTEIN; RECOMBINANT PROTEIN;

ALLERGENICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; BASOPHIL; BASOPHIL DEGRANULATION TEST; BINDING SITE; BODY TEMPERATURE; CONTROLLED STUDY; DISEASE SEVERITY; EFFECTOR CELL; ELECTRON MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC ANAPHYLAXIS; ANAPHYLAXIS; ANIMAL; BAGG ALBINO MOUSE; GENETICS; IMMUNOLOGY;

ALLERGENS; ANAPHYLAXIS; ANIMALS; ANTIGEN-ANTIBODY COMPLEX; EPITOPES; IMMUNOGLOBULIN E; MICE, INBRED BALB C; MYOGLOBIN; PLANT PROTEINS; RECOMBINANT PROTEINS;

EID: 84960874036     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.08.055     Document Type: Article

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