Interplay of atherogenic factors, protein intake and betatrophin levels in obese-metabolic syndrome patients treated with hypocaloric diets

International Journal of Obesity

Volumn 40, Issue 3, 2016, Pages 403-410

  Crujeiras, A B ^a,b   Zulet, M A ^b,c   Abete, I ^b,c   Amil, M ^a,b   Carreira, M C ^a,b   Martinez J A ^b,c   Casanueva, F F ^a,b  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c UNIVERSITY OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BETATROPHIN; FATTY ACID; GHRELIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; IRISIN; LEPTIN; PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; LIPASIN PROTEIN, HUMAN; PEPTIDE HORMONE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTHROPOMETRY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ATHEROGENIC DIET; BODY COMPOSITION; BODY MASS; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; FAT FREE MASS; FAT MASS; FATTY ACID BLOOD LEVEL; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; LOW CALORY DIET; MACRONUTRIENT; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN INTAKE; RISK FACTOR; SELF CONTROL; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; WEIGHT LOSS PROGRAM; ATHEROSCLEROSIS; CALORIC INTAKE; CALORIC RESTRICTION; DIET THERAPY; LONGITUDINAL STUDY; METABOLISM; MIDDLE AGED; OBESITY; PRACTICE GUIDELINE; TREATMENT OUTCOME; WEIGHT REDUCTION;

ATHEROSCLEROSIS; BIOMARKERS; BLOOD GLUCOSE; CALORIC RESTRICTION; DIET, REDUCING; ENERGY INTAKE; FEMALE; GUIDELINES AS TOPIC; HUMANS; LONGITUDINAL STUDIES; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY; PEPTIDE HORMONES; TREATMENT OUTCOME; WEIGHT LOSS;

EID: 84960813870     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2015.206     Document Type: Article

References (43)

1. Gutierrez-Fisac JL, Guallar-Castillon P, Leon-Munoz LM, Graciani A, Banegas JR, Rodriguez-Artalejo F. Prevalence of general and abdominal obesity in the adult population of Spain, 2008-2010: the ENRICA study. Obes Rev 2011; 13: 388-392.
2. Bray GA, Bellanger T. Epidemiology, trends, and morbidities of obesity and the metabolic syndrome. Endocrine 2006; 29: 109-117.
3. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2005; 365: 1415-1428.
4. Chaput JP, Tremblay A. Current and novel approaches to the drug therapy of obesity. Eur J Clin Pharmacol 2006; 62: 793-803.
5. Crujeiras AB, Carreira MC, Casanueva FF. Obesity and the future. New problems and new solutions. Endocrinol Nutr 2013; 60: 33-35.
6. Friedman JM. The function of leptin in nutrition, weight, and physiology. Nutr Rev 2002; 60: S1-S14; discussion S68-S84, 85-88.
7. Al-Massadi O, Crujeiras AB, Gonzalez RC, Pardo M, Dieguez C, Casanueva FF, et al. Age, sex, and lactating status regulate ghrelin secretion and GOAT mRNA levels from isolated rat stomach. Am J Physiol Endocrinol Metab 2010; 299: E341-E350.
8. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999; 402: 656-660.
9. Wynne K, Stanley S, Bloom S. The gut and regulation of body weight. J Clin Endocrinol Metab 2004; 89: 2576-2582.
10. Pedersen BK. Muscles and their myokines. J Exp Biol 2011; 214: 337-346.
11. Yi P, Park JS, Melton DA. Betatrophin: a hormone that controls pancreatic beta cell proliferation. Cell 2013; 153: 747-758.
12. Fu Z, Berhane F, Fite A, Seyoum B, Abou-Samra AB, Zhang R. Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity. Sci Rep 2014; 4: 5013.
13. Fu Z, Yao F, Abou-Samra AB, Zhang R. Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family. Biochem Biophys Res Commun 2013; 430: 1126-1131.
14. Quagliarini F, Wang Y, Kozlitina J, Grishin NV, Hyde R, Boerwinkle E, et al. Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci USA 2012; 109: 19751-19756.
15. Ren G, Kim JY, Smas CM. Identification of RIFL, a novel adipocyte-Enriched insulin target gene with a role in lipid metabolism. Am J Physiol Endocrinol Metab 2012; 303: E334-E351.
16. Wang Y, Quagliarini F, Gusarova V, Gromada J, Valenzuela DM, Cohen JC, et al. Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis. Proc Natl Acad Sci USA 2013; 110: 16109-16114.
17. Zhang R. Lipasin, a novel nutritionally-regulated liver-Enriched factor that regulates serum triglyceride levels. Biochem Biophys Res Commun 2012; 424: 786-792.
18. Chen X, Lu P, He W, Zhang J, Liu L, Yang Y, et al. Circulating betatrophin levels are increased in patients with type 2 diabetes and associated with insulin resistance. J Clin Endocrinol Metab 2015; 100: E96-E100.
19. Espes D, Lau J, Carlsson PO. Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes. Diabetologia 2014; 57: 50-53.
20. Hu H, Sun W, Yu S, Hong X, Qian W, Tang B, et al. Increased circulating levels of betatrophin in newly diagnosed type 2 diabetic patients. Diabetes Care 2014; 37: 2718-2722.
21. Wu S, Gao H, Ma Y, Fu L, Zhang C, Luo X. Characterisation of betatrophin concentrations in childhood and adolescent obesity and insulin resistance. Pediatr Diabetes 2014; e-pub ahead of print 21 November 2014; doi:10.1111/pedi.12233.
22. Abu-Farha M, Abubaker J, Al-Khairi I, Cherian P, Noronha F, Hu FB, et al. Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance. Sci Rep 2015; 5: 10949.
23. Fenzl A, Itariu BK, Kosi L, Fritzer-Szekeres M, Kautzky-Willer A, Stulnig TM, et al. Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals. Diabetologia 2014; 57: 1204-1208.
24. Guo K, Lu J, Yu H, Zhao F, Pan P, Zhang L, et al. Serum betatrophin concentrations are significantly increased in overweight but not in obese or type 2 diabetic individuals. Obesity (Silver Spring) 2015; 23: 793-797.
25. Gomez-Ambrosi J, Pascual E, Catalan V, Rodriguez A, Ramirez B, Silva C, et al. Circulating betatrophin concentrations are decreased in human obesity and type 2 diabetes. J Clin Endocrinol Metab 2014; 99: E2004-E2009.
26. Alberti KG, Zimmet P, Shaw J. The metabolic syndrome-A new worldwide definition. Lancet 2005; 366: 1059-1062.
27. Lopez-Legarrea P, de la Iglesia R, Abete I, Bondia-Pons I, Navas-Carretero S, Forga L, et al. Short-Term role of the dietary total antioxidant capacity in two hypocaloric regimes on obese with metabolic syndrome symptoms: the RESMENA randomized controlled trial. Nutr Metab (Lond) 2013; 10: 22.
28. de la Iglesia R, Lopez-Legarrea P, Celada P, Sanchez-Muniz FJ, Martinez JA, Zulet MA. Beneficial effects of the RESMENA dietary pattern on oxidative stress in patients suffering from metabolic syndrome with hyperglycemia are associated to dietary TAC and fruit consumption. Int J Mol Sci 2013; 14: 6903-6919.
29. Crujeiras AB, Parra D, Goyenechea E, Abete I, Martinez JA. Tachyphylaxis effects on postprandial oxidative stress and mitochondrial-related gene expression in overweight subjects after a period of energy restriction. Eur J Nutr 2009; 48: 341-347.
30. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-Density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499-502.
31. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
32. Crujeiras AB, Goyenechea E, Abete I, Lage M, Carreira MC, Martinez JA, et al. Weight regain after a diet-induced loss is predicted by higher baseline leptin and lower ghrelin plasma levels. J Clin Endocrinol Metab 2010; 95: 5037-5044.
33. Martinez-Gonzalez MA, Lopez-Fontana C, Varo JJ, Sanchez-Villegas A, Martinez JA. Validation of the Spanish version of the physical activity questionnaire used in the Nurses' Health Study and the Health Professionals' Follow-up Study. Public Health Nutr 2005; 8: 920-927.
34. Li Y, Teng C. Angiopoietin-like proteins 3, 4 and 8: regulating lipid metabolism and providing new hope for metabolic syndrome. J Drug Target 2014; 22: 679-687.
35. Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, et al. A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol 2010; 28: 749-755.
36. Fu Z, Abou-Samra AB, Zhang R. An explanation for recent discrepancies in levels of human circulating betatrophin. Diabetologia 2014; 57: 2232-2234.
37. Astrup A, Raben A, Geiker N. The role of higher protein diets in weight control and obesity-related comorbidities. Int J Obes (Lond) 2014; 39: 721-726.
38. Westerterp-Plantenga MS, Lemmens SG, Westerterp KR. Dietary protein - its role in satiety, energetics, weight loss and health. Br J Nutr 2012; 108: S105-S112.
39. Larsen TM, Dalskov SM, van Baak M, Jebb SA, Papadaki A, Pfeiffer AF, et al. Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med 2010; 363: 2102-2113.
40. Alkerwi A, Sauvageot N, Buckley JD, Donneau AF, Albert A, Guillaume M, et al. The potential impact of animal protein intake on global and abdominal obesity: evidence from the Observation of Cardiovascular Risk Factors in Luxembourg (ORISCAV-LUX) study. Public Health Nutr 2015; 18: 1831-1838.
41. Lin Y, Mouratidou T, Vereecken C, Kersting M, Bolca S, de Moraes AC, et al. Dietary animal and plant protein intakes and their associations with obesity and cardio-metabolic indicators in European adolescents: the HELENA crosssectional study. Nutr J 2015; 14: 10.
42. Lopez-Legarrea P, de la Iglesia R, Abete I, Navas-Carretero S, Martinez JA, Zulet MA. The protein type within a hypocaloric diet affects obesity-related inflammation: the RESMENA project. Nutrition 2014; 30: 424-429.
43. Gogebakan O, Kohl A, Osterhoff MA, van Baak MA, Jebb SA, Papadaki A, et al. Effects of weight loss and long-Term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: the diet, obesity, and genes (DiOGenes) study: a randomized, controlled trial. Circulation 2011; 124: 2829-2838.