-
1
-
-
84864244742
-
The rising problem of antimicrobial resistance in the intensive care unit
-
22112929
-
Brusselaers N, Vogelaers D, Blot S (2011) The rising problem of antimicrobial resistance in the intensive care unit. Ann Intensive Care 1:47. doi: 10.1186/2110-5820-1-47 PMID: 22112929
-
(2011)
Ann Intensive Care
, vol.1
, pp. 47
-
-
Brusselaers, N.1
Vogelaers, D.2
Blot, S.3
-
2
-
-
77950218147
-
Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department
-
20048677
-
Gaieski DF, Mikkelsen ME, Band RA, Pines JM, Massone R, Furia FF, et al. (2010) Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med 38:1045-1053. doi: 10.1097/CCM. 0b013e3181cc4824 PMID: 20048677
-
(2010)
Crit Care Med
, vol.38
, pp. 1045-1053
-
-
Gaieski, D.F.1
Mikkelsen, M.E.2
Band, R.A.3
Pines, J.M.4
Massone, R.5
Furia, F.F.6
-
3
-
-
0347122086
-
Impact of adequate empirical antibiotic therapy on the outcome of patients admitted to the intensive care unit with sepsis
-
14668610
-
Garnacho-Montero J, Garcia-Garmendia JL, Barrero-Almodovar A, Jimenez-Jimenez FJ, Perez-Paredes C, Ortiz-Leyba C (2003) Impact of adequate empirical antibiotic therapy on the outcome of patients admitted to the intensive care unit with sepsis. Crit Care Med 31:2742-2751. PMID: 14668610
-
(2003)
Crit Care Med
, vol.31
, pp. 2742-2751
-
-
Garnacho-Montero, J.1
Garcia-Garmendia, J.L.2
Barrero-Almodovar, A.3
Jimenez-Jimenez, F.J.4
Perez-Paredes, C.5
Ortiz-Leyba, C.6
-
4
-
-
33744527833
-
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
-
16625125
-
Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, et al. (2006) Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 34:1589-1596. PMID: 16625125
-
(2006)
Crit Care Med
, vol.34
, pp. 1589-1596
-
-
Kumar, A.1
Roberts, D.2
Wood, K.E.3
Light, B.4
Parrillo, J.E.5
Sharma, S.6
-
5
-
-
84555171441
-
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
-
Toprak E, Veres A, Michel JB, Chait R, Hartl DL, Kishony R (2012) Evolutionary paths to antibiotic resistance under dynamically sustained drug selection. Nat Genet 44:101-105.
-
(2012)
Nat Genet
, vol.44
, pp. 101-105
-
-
Toprak, E.1
Veres, A.2
Michel, J.B.3
Chait, R.4
Hartl, D.L.5
Kishony, R.6
-
6
-
-
79957658234
-
De novo acquisition of resistance to three antibiotics by Escherichia coli
-
21235391
-
van der Horst MA, Schuurmans JM, Smid MC, Koenders BB, Ter Kuile BH (2011) De Novo Acquisition of Resistance to Three Antibiotics by Escherichia coli. Microb Drug Resist 17:141-147. doi: 10.1089/mdr.2010.0101 PMID: 21235391
-
(2011)
Microb Drug Resist
, vol.17
, pp. 141-147
-
-
Van Der Horst, M.A.1
Schuurmans, J.M.2
Smid, M.C.3
Koenders, B.B.4
Ter Kuile, B.H.5
-
7
-
-
33847045214
-
Mutant selection window hypothesis updated
-
17278059
-
Drlica K, Zhao X (2007) Mutant selection window hypothesis updated. Clin Infect Dis 44:681-688. PMID: 17278059
-
(2007)
Clin Infect Dis
, vol.44
, pp. 681-688
-
-
Drlica, K.1
Zhao, X.2
-
8
-
-
84880271453
-
Compensation of the metabolic costs of antibiotic resistance by physiological adaptation in Escherichia coli
-
23716056
-
Handel N, Schuurmans JM, Brul S, Ter Kuile BH (2013) Compensation of the Metabolic Costs of Antibiotic Resistance by Physiological Adaptation in Escherichia coli. Antimicrob Agents Chemother 57:3752-3762. doi: 10.1128/AAC.02096-12 PMID: 23716056
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 3752-3762
-
-
Handel, N.1
Schuurmans, J.M.2
Brul, S.3
Ter Kuile, B.H.4
-
9
-
-
84905393512
-
Interaction between mutations and regulation of gene expression during development of de novo antibiotic resistance
-
24841263
-
Handel N, Schuurmans JM, Feng Y, Brul S, Ter Kuile BH (2014) Interaction between Mutations and Regulation of Gene Expression during Development of De Novo Antibiotic Resistance. Antimicrob Agents Chemother 58:4371-4379. doi: 10.1128/AAC.02892-14 PMID: 24841263
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4371-4379
-
-
Handel, N.1
Schuurmans, J.M.2
Feng, Y.3
Brul, S.4
Ter Kuile, B.H.5
-
10
-
-
33745481821
-
Antimicrobial resistance: Factors and outcomes
-
16678001 vii
-
Fish DN, Ohlinger MJ (2006) Antimicrobial resistance: factors and outcomes. Crit Care Clin 22:291-311, vii. PMID: 16678001
-
(2006)
Crit Care Clin
, vol.22
, pp. 291-311
-
-
Fish, D.N.1
Ohlinger, M.J.2
-
11
-
-
49949099257
-
Antibiotic resistance-what's dosing got to do with it?
-
18596628
-
Roberts JA, Kruger P, Paterson DL, Lipman J (2008) Antibiotic resistance-what's dosing got to do with it? Crit Care Med 36:2433-2440. doi: 10.1097/CCM.0b013e318180fe62 PMID: 18596628
-
(2008)
Crit Care Med
, vol.36
, pp. 2433-2440
-
-
Roberts, J.A.1
Kruger, P.2
Paterson, D.L.3
Lipman, J.4
-
12
-
-
0347273599
-
Reappraisal of attributable mortality in critically ill patients with nosocomial bacteraemia involving Pseudomonas aeruginosa
-
12495681
-
Blot S, Vandewoude K, Hoste E, Colardyn F (2003) Reappraisal of attributable mortality in critically ill patients with nosocomial bacteraemia involving Pseudomonas aeruginosa. J Hosp Infect 53:18-24. PMID: 12495681
-
(2003)
J Hosp Infect
, vol.53
, pp. 18-24
-
-
Blot, S.1
Vandewoude, K.2
Hoste, E.3
Colardyn, F.4
-
13
-
-
0030067765
-
Continuous infusion versus intermittent administration of ceftazidime in critically ill patients with suspected gram-negative infections
-
8851594
-
Benko AS, Cappelletty DM, Kruse JA, Rybak MJ (1996) Continuous infusion versus intermittent administration of ceftazidime in critically ill patients with suspected gram-negative infections. Antimicrob Agents Chemother 40:691-695. PMID: 8851594
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 691-695
-
-
Benko, A.S.1
Cappelletty, D.M.2
Kruse, J.A.3
Rybak, M.J.4
-
14
-
-
84862534688
-
Population pharmacokinetics of four beta-lactams in critically ill septic patients comedicated with amikacin
-
22503878
-
Delattre IK, Musuamba FT, Jacqmin P, Taccone FS, Laterre PF, Verbeeck RK, et al. (2012) Population pharmacokinetics of four beta-lactams in critically ill septic patients comedicated with amikacin. Clin Biochem 45:780-786. doi: 10.1016/j.clinbiochem.2012.03.030 PMID: 22503878
-
(2012)
Clin Biochem
, vol.45
, pp. 780-786
-
-
Delattre, I.K.1
Musuamba, F.T.2
Jacqmin, P.3
Taccone, F.S.4
Laterre, P.F.5
Verbeeck, R.K.6
-
15
-
-
77953710477
-
Stability of meropenem and doripenem solutions for administration by continuous infusion
-
20176578
-
Berthoin K, Le Duff CS, Marchand-Brynaert J, Carryn S, Tulkens PM (2010) Stability of meropenem and doripenem solutions for administration by continuous infusion. J Antimicrob Chemother 65:1073-1075. doi: 10.1093/jac/dkq044 PMID: 20176578
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 1073-1075
-
-
Berthoin, K.1
Le Duff, C.S.2
Marchand-Brynaert, J.3
Carryn, S.4
Tulkens, P.M.5
-
16
-
-
2942534525
-
Optimization of antibiotic dosing schedules in the light of increasing antibiotic resistance
-
15482188
-
Smith SV, Gould IM (2004) Optimization of antibiotic dosing schedules in the light of increasing antibiotic resistance. Expert Rev Anti Infect Ther 2:227-234. PMID: 15482188
-
(2004)
Expert Rev Anti Infect Ther
, vol.2
, pp. 227-234
-
-
Smith, S.V.1
Gould, I.M.2
-
18
-
-
34948907854
-
Development of resistance in wildtype and hypermutable Pseudomonas aeruginosa strains exposed to clinical pharmacokinetic profiles of meropenem and ceftazidime simulated in vitro
-
17682103
-
Henrichfreise B, Wiegand I, Luhmer-Becker I, Wiedemann B (2007) Development of resistance in wildtype and hypermutable Pseudomonas aeruginosa strains exposed to clinical pharmacokinetic profiles of meropenem and ceftazidime simulated in vitro. Antimicrob Agents Chemother 51:3642-3649. PMID: 17682103
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3642-3649
-
-
Henrichfreise, B.1
Wiegand, I.2
Luhmer-Becker, I.3
Wiedemann, B.4
-
19
-
-
84863366486
-
Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli
-
22232279
-
Singh R, Swick MC, Ledesma KR, Yang Z, Hu M, Zechiedrich L, et al. (2012) Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli. Antimicrob Agents Chemother 56:1680-1685. doi: 10.1128/AAC.05693-11 PMID: 22232279
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 1680-1685
-
-
Singh, R.1
Swick, M.C.2
Ledesma, K.R.3
Yang, Z.4
Hu, M.5
Zechiedrich, L.6
-
20
-
-
84925343017
-
The fitness costs of antibiotic resistance mutations
-
25861385
-
Melnyk AH, Wong A, Kassen R (2015) The fitness costs of antibiotic resistance mutations. Evol Appl 8:273-283. doi: 10.1111/eva.12196 PMID: 25861385
-
(2015)
Evol Appl
, vol.8
, pp. 273-283
-
-
Melnyk, A.H.1
Wong, A.2
Kassen, R.3
-
21
-
-
84992206602
-
Experimental simulation of the effects of an initial antibiotic treatment on a subsequent treatment after initial therapy failure
-
Feng Y, Händel N, de Groot M, Brul S, Schultsz C, ter Kuile B (2014) Experimental Simulation of the Effects of an Initial Antibiotic Treatment on a Subsequent Treatment after Initial Therapy Failure. Antibiotics 3:49.
-
(2014)
Antibiotics
, vol.3
, pp. 49
-
-
Feng, Y.1
Händel, N.2
De Groot, M.3
Brul, S.4
Schultsz, C.5
Ter Kuile, B.6
-
22
-
-
0034902666
-
Optimizing antibiotic therapy in the intensive care unit setting
-
11511331
-
Kollef MH (2001) Optimizing antibiotic therapy in the intensive care unit setting. Crit Care 5:189-195. PMID: 11511331
-
(2001)
Crit Care
, vol.5
, pp. 189-195
-
-
Kollef, M.H.1
-
23
-
-
84891949316
-
Contribution of phenotypic heterogeneity to adaptive antibiotic resistance
-
24351930
-
Sanchez-Romero MA, Casadesus J (2014) Contribution of phenotypic heterogeneity to adaptive antibiotic resistance. Proc Natl Acad Sci U S A 111:355-360. doi: 10.1073/pnas.1316084111 PMID: 24351930
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 355-360
-
-
Sanchez-Romero, M.A.1
Casadesus, J.2
-
24
-
-
77956328000
-
Bacterial charity work leads to population-wide resistance
-
20811456
-
Lee HH, Molla MN, Cantor CR, Collins JJ (2010) Bacterial charity work leads to population-wide resistance. Nature 467:82-85. doi: 10.1038/nature09354 PMID: 20811456
-
(2010)
Nature
, vol.467
, pp. 82-85
-
-
Lee, H.H.1
Molla, M.N.2
Cantor, C.R.3
Collins, J.J.4
-
25
-
-
84907736803
-
Collective antibiotic resistance: Mechanisms and implications
-
25271119
-
Vega NM, Gore J (2014) Collective antibiotic resistance: mechanisms and implications. Curr Opin Microbiol 21:28-34. doi: 10.1016/j.mib.2014.09.003 PMID: 25271119
-
(2014)
Curr Opin Microbiol
, vol.21
, pp. 28-34
-
-
Vega, N.M.1
Gore, J.2
-
26
-
-
84920379887
-
Emergence of antibiotic resistance from multinucleated bacterial filaments
-
25492931
-
Bos J, Zhang Q, Vyawahare S, Rogers E, Rosenberg SM, Austin RH (2015) Emergence of antibiotic resistance from multinucleated bacterial filaments. Proc Natl Acad Sci U S A 112:178-183. doi: 10. 1073/pnas.1420702111 PMID: 25492931
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 178-183
-
-
Bos, J.1
Zhang, Q.2
Vyawahare, S.3
Rogers, E.4
Rosenberg, S.M.5
Austin, R.H.6
-
28
-
-
79951956042
-
Creeping baselines and adaptive resistance to antibiotics
-
21288762
-
Fernandez L, Breidenstein EB, Hancock RE (2011) Creeping baselines and adaptive resistance to antibiotics. Drug Resist Updat 14:1-21. doi: 10.1016/j.drup. 2011.01.001 PMID: 21288762
-
(2011)
Drug Resist Updat
, vol.14
, pp. 1-21
-
-
Fernandez, L.1
Breidenstein, E.B.2
Hancock, R.E.3
-
29
-
-
0035113461
-
Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth
-
11226851
-
Hoiby N, Krogh Johansen H, Moser C, Song Z, Ciofu O, Kharazmi A (2001) Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth. Microbes Infect 3:23-35. PMID: 11226851
-
(2001)
Microbes Infect
, vol.3
, pp. 23-35
-
-
Hoiby, N.1
Krogh Johansen, H.2
Moser, C.3
Song, Z.4
Ciofu, O.5
Kharazmi, A.6
-
30
-
-
84866321632
-
Effect of systemic infection induced by Pseudomonas aeruginosa on the brain uptake of colistin in mice
-
22850514
-
Jin L, Li J, Nation RL, Nicolazzo JA (2012) Effect of systemic infection induced by Pseudomonas aeruginosa on the brain uptake of colistin in mice. Antimicrob Agents Chemother 56:5240-5246. doi: 10. 1128/AAC.00713-12 PMID: 22850514
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 5240-5246
-
-
Jin, L.1
Li, J.2
Nation, R.L.3
Nicolazzo, J.A.4
-
31
-
-
0033936567
-
Mutation frequencies and antibiotic resistance
-
10858329
-
Martinez JL, Baquero F (2000) Mutation frequencies and antibiotic resistance. Antimicrob Agents Chemother 44:1771-1777. PMID: 10858329
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1771-1777
-
-
Martinez, J.L.1
Baquero, F.2
-
32
-
-
84964315873
-
Genomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli
-
25281544
-
Mogre A, Sengupta T, Veetil RT, Ravi P, Seshasayee AS (2014) Genomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli. DNA Res 21:711-726. doi: 10.1093/dnares/dsu032 PMID: 25281544
-
(2014)
DNA Res
, vol.21
, pp. 711-726
-
-
Mogre, A.1
Sengupta, T.2
Veetil, R.T.3
Ravi, P.4
Seshasayee, A.S.5
-
33
-
-
84906751681
-
Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution
-
24962091
-
Oz T, Guvenek A, Yildiz S, Karaboga E, Tamer YT, Mumcuyan N, et al. (2014) Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution. Mol Biol Evol 31:2387-2401. doi: 10.1093/molbev/msu191 PMID: 24962091
-
(2014)
Mol Biol Evol
, vol.31
, pp. 2387-2401
-
-
Oz, T.1
Guvenek, A.2
Yildiz, S.3
Karaboga, E.4
Tamer, Y.T.5
Mumcuyan, N.6
-
34
-
-
33748693294
-
The biological cost of mutational antibiotic resistance: Any practical conclusions?
-
16890008
-
Andersson DI (2006) The biological cost of mutational antibiotic resistance: any practical conclusions? Curr Opin Microbiol 9:461-465. PMID: 16890008
-
(2006)
Curr Opin Microbiol
, vol.9
, pp. 461-465
-
-
Andersson, D.I.1
-
35
-
-
84907587037
-
The effects of vaccination and immunity on bacterial infection dynamics in vivo
-
25233077
-
Coward C, Restif O, Dybowski R, Grant AJ, Maskell DJ, Mastroeni P (2014) The effects of vaccination and immunity on bacterial infection dynamics in vivo. PLoS Pathog 10:e1004359. doi: 10.1371/journal.ppat.1004359 PMID: 25233077
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004359
-
-
Coward, C.1
Restif, O.2
Dybowski, R.3
Grant, A.J.4
Maskell, D.J.5
Mastroeni, P.6
|