Triiodothyronine administration in a model of septic shock: A randomized blinded placebo-controlled trial

Critical Care Medicine

Volumn 44, Issue 6, 2016, Pages 1153-1160

  Maiden, Matthew J ^a,b   Chapman, Marianne J ^a,b   Torpy, David J ^a   Kuchel, Timothy R ^c   Clarke, Iain J ^d   Nash, Coralie H ^b   Fraser, Jonathan D ^a,b   Ludbrook, Guy L ^b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c SOUTH AUSTRALIAN HEALTH AND MEDICAL RESEARCH INSTITUTE   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

drug evaluation; euthyroid sick syndromes; hydrocortisone; multiple organ failure; preclinical; randomized controlled trial; septic; shock

Indexed keywords

3,3',5' TRIIODOTHYRONINE; HYDROCORTISONE; LIOTHYRONINE; NORADRENALIN; PLACEBO; THYROXINE; ANTIINFLAMMATORY AGENT;

AIR CONDITIONING; ARTICLE; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG INFUSION; DRUG SAFETY; ESCHERICHIA COLI INFECTION; EXPERIMENTAL SHEEP; FLUID RESUSCITATION; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HEMODYNAMIC PARAMETERS; HORMONAL THERAPY; LIOTHYRONINE BLOOD LEVEL; MEAN ARTERIAL PRESSURE; METABOLIC PARAMETERS; OUTCOME ASSESSMENT; OVINE MODEL; PARENTERAL NUTRITION; PRIORITY JOURNAL; RANDOMIZATION; SEDATION; SEPTIC SHOCK; ANIMAL; ARTERIAL PRESSURE; BLOOD; COMBINATION DRUG THERAPY; DISEASE MODEL; DRUG EFFECTS; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; PATHOPHYSIOLOGY; SHEEP; SHOCK, SEPTIC; SINGLE BLIND PROCEDURE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTERIAL PRESSURE; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FEMALE; HYDROCORTISONE; INFUSIONS, INTRAVENOUS; NOREPINEPHRINE; RANDOM ALLOCATION; SHEEP; SHOCK, SEPTIC; SINGLE-BLIND METHOD; TRIIODOTHYRONINE;

EID: 84960391882     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001644     Document Type: Article

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