Hypothalamic neurogenesis persists in the aging brain and is controlled by energy-sensing IGF-I pathway

Neurobiology of Aging

Volumn 41, Issue , 2016, Pages 64-72

  Chaker, Zayna ^a,b,c,e   George, Caroline ^a,b   Petrovska, Marija ^b   Caron, Jean Baptiste ^c   Lacube, Philippe ^a,b   Caillé, Isabelle ^b,d   Holzenberger, Martin ^a,b  

^a HÔPITAL SAINT ANTOINE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d Département de Biologie   (France)

^e UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Adult neurogenesis; Conditional mutagenesis; GHRH; Hypothalamus; IGF I; Tanycyte

Indexed keywords

GROWTH HORMONE RELEASING FACTOR; SOMATOMEDIN C; INSULIN-LIKE GROWTH FACTOR-1, MOUSE;

ADULT; AGING; ANIMAL CELL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRAIN NERVE CELL; CELL POPULATION; CELL SELF-RENEWAL; CONTROLLED STUDY; HYPOTHALAMUS; HYPOTHALAMUS NUCLEUS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; MALE; MEDIAN EMINENCE; MUTAGENESIS; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; TANYCYTE; ANIMAL; ANIMAL MODEL; CELL PLASTICITY; CYTOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; MACROGLIA; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

AGING; ANIMALS; CELL PLASTICITY; CELL SELF RENEWAL; EPENDYMOGLIAL CELLS; HYPOTHALAMUS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE, TRANSGENIC; MODELS, ANIMAL; NEUROGENESIS; SIGNAL TRANSDUCTION;

EID: 84960348047     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.02.008     Document Type: Article

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