Increased bacterial load and expression of antimicrobial peptides in skin of barrier-deficient mice with reduced cancer susceptibility

Journal of Investigative Dermatology

Volumn 136, Issue 1, 2016, Pages 99-106

  Natsuga, Ken ^a,b   Cipolat, Sara ^a,c   Watt, Fiona M ^c  

^a CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 3; BETA DEFENSIN 6; CYCLIC AMP; ELASTASE 2; ENVOPLAKIN; INVOLUCRIN; LYMPHOCYTE ANTIGEN RECEPTOR; MYELOPEROXIDASE; NATURAL KILLER CELL RECEPTOR NKG2D; PERIPLAKIN; RAE 1 PROTEIN; STRATUM CORNEUM CHYMOTRYPTIC ENZYME; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; MEMBRANE PROTEIN; PEROXIDASE; PROTEIN PRECURSOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; ATOPY; BACTERIAL COUNT; BACTERIAL LOAD; BREEDING; CANCER SUSCEPTIBILITY; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; EPIDERMIS; GAMMA DELTA T LYMPHOCYTE; HYPERKERATOSIS; INNATE IMMUNITY; KERATINOCYTE; LEUKOCYTE ACTIVATION; MOUSE; NONHUMAN; PARAKERATOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN FLORA; SKIN PENETRATION; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; DEFICIENCY; DISEASE MODEL; DISEASE PREDISPOSITION; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDEMIOLOGY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; METABOLISM; MICROBIOLOGY; MICROFLORA; NONPARAMETRIC TEST; PATHOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; SKIN; SKIN ABSORPTION; SKIN NEOPLASMS;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL LOAD; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IN SITU HYBRIDIZATION, FLUORESCENCE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICROBIOTA; PEROXIDASE; PROTEIN PRECURSORS; REAL-TIME POLYMERASE CHAIN REACTION; SKIN; SKIN ABSORPTION; SKIN NEOPLASMS; STATISTICS, NONPARAMETRIC;

EID: 84960192284     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/JID.2015.383     Document Type: Article

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