Charge Type, Charge Spacing, and Hydrophobicity of Arginine-Rich Cell-Penetrating Peptides Dictate Gene Transfection

Molecular Pharmaceutics

Volumn 13, Issue 3, 2016, Pages 1047-1057

  Alhakamy, Nabil A ^a   Dhar, Prajnaparamita ^a,b   Berkland, Cory J ^a,b  

^a UNIVERSITY OF KANSAS   (United States)

^b University of Kansas   (United States)

Author keywords

amphiphilic; arginine rich; calcium chloride; cell penetrating peptides; gene delivery; hydrophilic; nonviral; plasmid DNA; polyarginine; transfection

Indexed keywords

ARGININE; ARGININE DERIVATIVE; CELL PENETRATING PEPTIDE; NANOPARTICLE; PLASMID DNA; POLYARGININE R9 PEPTIDE; RA9 PEPTIDE; RH9 PEPTIDE; RL9 PEPTIDE; RW9 PEPTIDE; UNCLASSIFIED DRUG; CALCIUM; LUCIFERASE; PEPTIDE; POLYARGININE; POLYETHYLENEIMINE;

A549 CELL LINE; ARTICLE; CELL MEMBRANE PERMEABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; GENE EXPRESSION; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYDROPHOBICITY; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENE TRANSFER; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL CULTURE;

CALCIUM; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMANS; LUCIFERASES; LUNG NEOPLASMS; NANOPARTICLES; PEPTIDES; POLYETHYLENEIMINE; TUMOR CELLS, CULTURED;

EID: 84960131635     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00871     Document Type: Article

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