Molecular parameters of siRNA-cell penetrating peptide nanocomplexes for efficient cellular delivery

ACS Nano

Volumn 7, Issue 5, 2013, Pages 3797-3807

  Van Asbeck, Alexander H ^a,b   Beyerle, Andrea ^b   McNeill, Hesta ^b   Bovee Geurts, Petra H M ^a   Lindberg, Staffan ^c   Verdurmen, Wouter P R ^a   Hällbrink, Mattias ^c   Langel, Ülo ^c   Heidenreich, Olaf ^b   Brock, Roland ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

cell penetrating peptides; drug delivery; electrostatic; oligonucleotide nanoparticles; siRNA therapeutics; transfection

Indexed keywords

CELL-PENETRATING PEPTIDE; INTRACELLULAR DELIVERY; MOLECULAR PARAMETERS; NANOPARTICLE FORMATION; PHYSICOCHEMICAL PROPERTY; SIRNA THERAPEUTICS; TRANSFECTION; TRANSFECTION AGENTS;

ASSOCIATION REACTIONS; BODY FLUIDS; CELLS; CYTOLOGY; DRUG DELIVERY; ELECTROSTATICS; GENE EXPRESSION; NANOPARTICLES; OLIGONUCLEOTIDES; OPTIMIZATION; PEPTIDES;

MOLECULAR BIOLOGY;

CELL PENETRATING PEPTIDE; DRUG CARRIER; NANOMATERIAL; PLASMA PROTEIN; SMALL INTERFERING RNA;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN STABILITY; TUMOR CELL LINE;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLOOD PROTEINS; CELL LINE, TUMOR; CELL-PENETRATING PEPTIDES; DRUG CARRIERS; HUMANS; MOLECULAR SEQUENCE DATA; NANOSTRUCTURES; PROTEIN STABILITY; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84878323179     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn305754c     Document Type: Article

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