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Volumn 22, Issue 4, 2016, Pages 271-273

Combinatorial Antigen Targeting: Ideal T-Cell Sensing and Anti-Tumor Response

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; NOTCH RECEPTOR; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

EID: 84959926108     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2016.02.009     Document Type: Short Survey
Times cited : (11)

References (12)
  • 1
    • 0037264471 scopus 로고    scopus 로고
    • Targeting tumours with genetically enhanced T lymphocytes
    • Sadelain M., et al. Targeting tumours with genetically enhanced T lymphocytes. Nat. Rev. Cancer 2003, 3:35-45.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 35-45
    • Sadelain, M.1
  • 2
    • 84934268032 scopus 로고    scopus 로고
    • The pharmacology of second-generation chimeric antigen receptors
    • van der Stegen S.J., et al. The pharmacology of second-generation chimeric antigen receptors. Nat. Rev. Drug Discov. 2015, 14:499-509.
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 499-509
    • van der Stegen, S.J.1
  • 3
    • 84941686285 scopus 로고    scopus 로고
    • CAR therapy: the CD19 paradigm
    • Sadelain M. CAR therapy: the CD19 paradigm. J. Clin. Invest. 2015, 125:3392-3400.
    • (2015) J. Clin. Invest. , vol.125 , pp. 3392-3400
    • Sadelain, M.1
  • 4
    • 80455162464 scopus 로고    scopus 로고
    • Inducible apoptosis as a safety switch for adoptive cell therapy
    • Di Stasi A., et al. Inducible apoptosis as a safety switch for adoptive cell therapy. N. Engl. J. Med. 2011, 365:1673-1683.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1673-1683
    • Di Stasi, A.1
  • 5
    • 84924301768 scopus 로고    scopus 로고
    • Redirection of genetically engineered CAR-T cells using bifunctional small molecules
    • Kim M.S., et al. Redirection of genetically engineered CAR-T cells using bifunctional small molecules. J. Am. Chem. Soc. 2015, 137:2832-2835.
    • (2015) J. Am. Chem. Soc. , vol.137 , pp. 2832-2835
    • Kim, M.S.1
  • 6
    • 84945217637 scopus 로고    scopus 로고
    • Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
    • aab4077
    • Wu C.Y., et al. Remote control of therapeutic T cells through a small molecule-gated chimeric receptor. Science 2015, 350:aab4077.
    • (2015) Science , vol.350
    • Wu, C.Y.1
  • 7
    • 84891708419 scopus 로고    scopus 로고
    • PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses
    • 215ra172
    • Fedorov V.D., et al. PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses. Sci. Transl. Med. 2013, 5:215ra172.
    • (2013) Sci. Transl. Med. , vol.5
    • Fedorov, V.D.1
  • 8
    • 84872196489 scopus 로고    scopus 로고
    • Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
    • Kloss C.C., et al. Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells. Nat. Biotechnol. 2013, 31:71-75.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 71-75
    • Kloss, C.C.1
  • 9
    • 84958230998 scopus 로고    scopus 로고
    • Engineering customized cell sensing and response behaviors using synthetic Notch receptors
    • Morsut L., et al. Engineering customized cell sensing and response behaviors using synthetic Notch receptors. Cell 2016, 164:780-791.
    • (2016) Cell , vol.164 , pp. 780-791
    • Morsut, L.1
  • 10
    • 84958214384 scopus 로고    scopus 로고
    • Precision tumor recognition by T cells with combinatorial antigen-sensing circuits
    • Roybal K.T., et al. Precision tumor recognition by T cells with combinatorial antigen-sensing circuits. Cell 2016, 164:770-779.
    • (2016) Cell , vol.164 , pp. 770-779
    • Roybal, K.T.1
  • 11
    • 84937638491 scopus 로고    scopus 로고
    • Mechanical allostery: evidence for a force requirement in the proteolytic activation of Notch
    • Gordon W.R., et al. Mechanical allostery: evidence for a force requirement in the proteolytic activation of Notch. Dev. Cell 2015, 33:729-736.
    • (2015) Dev. Cell , vol.33 , pp. 729-736
    • Gordon, W.R.1
  • 12
    • 0036827724 scopus 로고    scopus 로고
    • Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus
    • Favre D., et al. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus. J. Virol. 2002, 76:11605-11611.
    • (2002) J. Virol. , vol.76 , pp. 11605-11611
    • Favre, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.