-
1
-
-
84908335908
-
Integrated genomic characterization of papillary thyroid carcinoma
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network. Integrated genomic characterization of papillary thyroid carcinoma. Cell. 2014;159(3):676-690.
-
(2014)
Cell
, vol.159
, Issue.3
, pp. 676-690
-
-
-
2
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
Lawrence MS, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013;499(7457):214-218.
-
(2013)
Nature
, vol.499
, Issue.7457
, pp. 214-218
-
-
Lawrence, M.S.1
-
3
-
-
65549128212
-
Anaplastic thyroid cancer: Molecular pathogenesis and emerging therapies
-
Smallridge RC, Marlow LA, Copland JA. Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies. Endocr Relat Cancer. 2009;16(1):17-44.
-
(2009)
Endocr Relat Cancer
, vol.16
, Issue.1
, pp. 17-44
-
-
Smallridge, R.C.1
Marlow, L.A.2
Copland, J.A.3
-
4
-
-
79952927806
-
Anaplastic thyroid cancer: A comprehensive review of novel therapy
-
Kojic SL, Strugnell SS, Wiseman SM. Anaplastic thyroid cancer: a comprehensive review of novel therapy. Expert Rev Anticancer Ther. 2011;11(3):387-402.
-
(2011)
Expert Rev Anticancer Ther
, vol.11
, Issue.3
, pp. 387-402
-
-
Kojic, S.L.1
Strugnell, S.S.2
Wiseman, S.M.3
-
5
-
-
77954760114
-
Anaplastic thyroid carcinoma: Pathogenesis and emerging therapies
-
Smallridge RC, Copland JA. Anaplastic thyroid carcinoma: pathogenesis and emerging therapies. Clin Oncol (R Coll Radiol). 2010;22(6):486-497.
-
(2010)
Clin Oncol (R Coll Radiol)
, vol.22
, Issue.6
, pp. 486-497
-
-
Smallridge, R.C.1
Copland, J.A.2
-
6
-
-
84907863603
-
Response and acquired resistance to everolimus in anaplastic thyroid cancer
-
Wagle N, et al. Response and acquired resistance to everolimus in anaplastic thyroid cancer. N Engl J Med. 2014;371(15):1426-1433.
-
(2014)
N Engl J Med
, vol.371
, Issue.15
, pp. 1426-1433
-
-
Wagle, N.1
-
7
-
-
84873641344
-
BRAF V600E inhibition in anaplastic thyroid cancer
-
Rosove MH, Peddi PF, Glaspy JA. BRAF V600E inhibition in anaplastic thyroid cancer. N Engl J Med. 2013;368(7):684-685.
-
(2013)
N Engl J Med
, vol.368
, Issue.7
, pp. 684-685
-
-
Rosove, M.H.1
Peddi, P.F.2
Glaspy, J.A.3
-
8
-
-
80053150200
-
Molecular genetics and diagnosis of thyroid cancer
-
Nikiforov YE, Nikiforova MN. Molecular genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol. 2011;7(10):569-580.
-
(2011)
Nat Rev Endocrinol
, vol.7
, Issue.10
, pp. 569-580
-
-
Nikiforov, Y.E.1
Nikiforova, M.N.2
-
9
-
-
66349098309
-
Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1
-
Ricarte-Filho JC, et al. Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1. Cancer Res. 2009;69(11):4885-4893.
-
(2009)
Cancer Res
, vol.69
, Issue.11
, pp. 4885-4893
-
-
Ricarte-Filho, J.C.1
-
10
-
-
28544452359
-
Mutation of the PIK3CA gene in anaplastic thyroid cancer
-
Garcia-Rostan G, et al. Mutation of the PIK3CA gene in anaplastic thyroid cancer. Cancer Res. 2005;65(22):10199-10207.
-
(2005)
Cancer Res
, vol.65
, Issue.22
, pp. 10199-10207
-
-
Garcia-Rostan, G.1
-
11
-
-
84895822573
-
Cell cycle deregulation and TP53 and RAS mutations are major events in poorly differentiated and undifferentiated thyroid carcinomas
-
Pita JM, Figueiredo IF, Moura MM, Leite V, Cavaco BM. Cell cycle deregulation and TP53 and RAS mutations are major events in poorly differentiated and undifferentiated thyroid carcinomas. J Clin Endocrinol Metab. 2014;99(3):E497-E507.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, Issue.3
, pp. E497-E507
-
-
Pita, J.M.1
Figueiredo, I.F.2
Moura, M.M.3
Leite, V.4
Cavaco, B.M.5
-
12
-
-
0033561515
-
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma
-
Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML, Rimm DL. Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res. 1999;59(8):1811-1815.
-
(1999)
Cancer Res
, vol.59
, Issue.8
, pp. 1811-1815
-
-
Garcia-Rostan, G.1
Tallini, G.2
Herrero, A.3
D'Aquila, T.G.4
Carcangiu, M.L.5
Rimm, D.L.6
-
13
-
-
19944426556
-
Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers
-
Kurihara T, et al. Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers. Thyroid. 2004;14(12):1020-1029.
-
(2004)
Thyroid
, vol.14
, Issue.12
, pp. 1020-1029
-
-
Kurihara, T.1
-
14
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, Koeffler HP. High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest. 1993;91(1):179-184.
-
(1993)
J Clin Invest
, vol.91
, Issue.1
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
15
-
-
0027215123
-
Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
-
Donghi R, Longoni A, Pilotti S, Michieli P, Della Porta G, Pierotti MA. Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland. J Clin Invest. 1993;91(4):1753-1760.
-
(1993)
J Clin Invest
, vol.91
, Issue.4
, pp. 1753-1760
-
-
Donghi, R.1
Longoni, A.2
Pilotti, S.3
Michieli, P.4
Della Porta, G.5
Pierotti, M.A.6
-
16
-
-
0027048387
-
P53 gene mutations associated with anaplastic transformation of human thyroid carcinomas
-
Nakamura T, et al. p53 gene mutations associated with anaplastic transformation of human thyroid carcinomas. Jpn J Cancer Res. 1992;83(12):1293-1298.
-
(1992)
Jpn J Cancer Res
, vol.83
, Issue.12
, pp. 1293-1298
-
-
Nakamura, T.1
-
17
-
-
84883711485
-
Frequent somatic TERT promoter mutations in thyroid cancer: Higher prevalence in advanced forms of the disease
-
Landa I, et al. Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease. J Clin Endocrinol Metab. 2013;98(9):E1562-E1566.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, Issue.9
, pp. E1562-E1566
-
-
Landa, I.1
-
18
-
-
84882805198
-
Highly prevalent TERT promoter mutations in aggressive thyroid cancers
-
Liu X, et al. Highly prevalent TERT promoter mutations in aggressive thyroid cancers. Endocr Relat Cancer. 2013;20(4):603-610.
-
(2013)
Endocr Relat Cancer
, vol.20
, Issue.4
, pp. 603-610
-
-
Liu, X.1
-
19
-
-
85028141478
-
The age-shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
-
Liu T, et al. The age-shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas. Oncogene. 2013;33(42):4978-4984.
-
(2013)
Oncogene
, vol.33
, Issue.42
, pp. 4978-4984
-
-
Liu, T.1
-
20
-
-
84899908886
-
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas
-
Melo M, et al. TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas. J Clin Endocrinol Metab. 2014;99(5):E754-E765.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, Issue.5
, pp. E754-E765
-
-
Melo, M.1
-
21
-
-
84926511800
-
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
-
Kunstman JW, et al. Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing. Hum Mol Genet. 2015;24(8):2318-2329.
-
(2015)
Hum Mol Genet
, vol.24
, Issue.8
, pp. 2318-2329
-
-
Kunstman, J.W.1
-
22
-
-
79960644632
-
Tumor-associated macrophages (TAMs) form an interconnected cellular supportive network in anaplastic thyroid carcinoma
-
Caillou B, et al. Tumor-associated macrophages (TAMs) form an interconnected cellular supportive network in anaplastic thyroid carcinoma. PLoS One. 2011;6(7):e22567.
-
(2011)
PLoS One
, vol.6
, Issue.7
, pp. e22567
-
-
Caillou, B.1
-
23
-
-
56649101166
-
Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer
-
Ryder M, Ghossein RA, Ricarte-Filho JC, Knauf JA, Fagin JA. Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer. Endocr Relat Cancer. 2008;15(4):1069-1074.
-
(2008)
Endocr Relat Cancer
, vol.15
, Issue.4
, pp. 1069-1074
-
-
Ryder, M.1
Ghossein, R.A.2
Ricarte-Filho, J.C.3
Knauf, J.A.4
Fagin, J.A.5
-
24
-
-
84928105158
-
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology
-
Cheng DT, et al. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. J Mol Diagn. 2015;17(3):251-264.
-
(2015)
J Mol Diagn
, vol.17
, Issue.3
, pp. 251-264
-
-
Cheng, D.T.1
-
25
-
-
33645307434
-
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
-
Kondo T, Ezzat S, Asa SL. Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer. 2006;6(4):292-306.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.4
, pp. 292-306
-
-
Kondo, T.1
Ezzat, S.2
Asa, S.L.3
-
26
-
-
34248177447
-
Poorly differentiated thyroid carcinoma: The Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach
-
Volante M, et al. Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. Am J Surg Pathol. 2007;31(8):1256-1264.
-
(2007)
Am J Surg Pathol
, vol.31
, Issue.8
, pp. 1256-1264
-
-
Volante, M.1
-
27
-
-
33644843087
-
Poorly differentiated thyroid carcinomas defined on the basis of mitosis and necrosis: A clinicopathologic study of 58 patients
-
Hiltzik D, et al. Poorly differentiated thyroid carcinomas defined on the basis of mitosis and necrosis: a clinicopathologic study of 58 patients. Cancer. 2006;106(6):1286-1295.
-
(2006)
Cancer
, vol.106
, Issue.6
, pp. 1286-1295
-
-
Hiltzik, D.1
-
28
-
-
84881030814
-
Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
-
Martin M, et al. Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3. Nat Genet. 2013;45(8):933-936.
-
(2013)
Nat Genet
, vol.45
, Issue.8
, pp. 933-936
-
-
Martin, M.1
-
29
-
-
84930677573
-
Cancer. The transcription factor gabp selectively binds and activates the mutant tert promoter in cancer
-
Bell RJ, et al. Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Science. 2015;348(6238):1036-1039.
-
(2015)
Science
, vol.348
, Issue.6238
, pp. 1036-1039
-
-
Bell, R.J.1
-
30
-
-
0026575904
-
Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland
-
Ito T, et al. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res. 1992;52(5):1369-1371.
-
(1992)
Cancer Res
, vol.52
, Issue.5
, pp. 1369-1371
-
-
Ito, T.1
-
31
-
-
0032968315
-
Mutations of p53 in thyroid carcinoma with an insular component
-
Takeuchi Y, Daa T, Kashima K, Yokoyama S, Nakayama I, Noguchi S. Mutations of p53 in thyroid carcinoma with an insular component. Thyroid. 1999;9(4):377-381.
-
(1999)
Thyroid
, vol.9
, Issue.4
, pp. 377-381
-
-
Takeuchi, Y.1
Daa, T.2
Kashima, K.3
Yokoyama, S.4
Nakayama, I.5
Noguchi, S.6
-
32
-
-
84903629564
-
ATM signalling and cancer
-
Cremona CA, Behrens A. ATM signalling and cancer. Oncogene. 2014;33(26):3351-3360.
-
(2014)
Oncogene
, vol.33
, Issue.26
, pp. 3351-3360
-
-
Cremona, C.A.1
Behrens, A.2
-
33
-
-
84908693041
-
Vulnerabilities of mutant SWI/SNF complexes in cancer
-
Helming KC, Wang X, Roberts CW. Vulnerabilities of mutant SWI/SNF complexes in cancer. Cancer Cell. 2014;26(3):309-317.
-
(2014)
Cancer Cell
, vol.26
, Issue.3
, pp. 309-317
-
-
Helming, K.C.1
Wang, X.2
Roberts, C.W.3
-
34
-
-
84938065576
-
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains
-
Alekseyenko AA, et al. The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains. Genes Dev. 2015;29(14):1507-1523.
-
(2015)
Genes Dev
, vol.29
, Issue.14
, pp. 1507-1523
-
-
Alekseyenko, A.A.1
-
35
-
-
39049141295
-
Indirect macrophage responses to ionizing radiation: Implications for genotype-dependent bystander signaling
-
Coates PJ, Rundle JK, Lorimore SA, Wright EG. Indirect macrophage responses to ionizing radiation: implications for genotype-dependent bystander signaling. Cancer Res. 2008;68(2):450-456.
-
(2008)
Cancer Res
, vol.68
, Issue.2
, pp. 450-456
-
-
Coates, P.J.1
Rundle, J.K.2
Lorimore, S.A.3
Wright, E.G.4
-
36
-
-
10744222003
-
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas
-
Nikiforova MN, et al. BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. J Clin Endocrinol Metab. 2003;88(11):5399-5404.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.11
, pp. 5399-5404
-
-
Nikiforova, M.N.1
-
37
-
-
49249127826
-
Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers
-
Liu Z, et al. Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers. J Clin Endocrinol Metab. 2008;93(8):3106-3116.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.8
, pp. 3106-3116
-
-
Liu, Z.1
-
38
-
-
0043170833
-
BRAF mutations and RET/ PTC rearrangements are alternative events in the etiopathogenesis of PTC
-
Soares P, et al. BRAF mutations and RET/ PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene. 2003;22(29):4578-4580.
-
(2003)
Oncogene
, vol.22
, Issue.29
, pp. 4578-4580
-
-
Soares, P.1
-
39
-
-
30044436911
-
The role of microRNA genes in papillary thyroid carcinoma
-
He H, et al. The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A. 2005;102(52):19075-19080.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.52
, pp. 19075-19080
-
-
He, H.1
-
40
-
-
13444311710
-
Genetic alterations involved in the transition from well-differentiated to poorly dif-ferentiated and anaplastic thyroid carcinomas
-
Nikiforov YE. Genetic alterations involved in the transition from well-differentiated to poorly dif-ferentiated and anaplastic thyroid carcinomas. Endocr Pathol. 2004;15(4):319-327.
-
(2004)
Endocr Pathol
, vol.15
, Issue.4
, pp. 319-327
-
-
Nikiforov, Y.E.1
-
41
-
-
0026763062
-
Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype
-
Santoro M, et al. Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype. J Clin Invest. 1992;89(5):1517-1522.
-
(1992)
J Clin Invest
, vol.89
, Issue.5
, pp. 1517-1522
-
-
Santoro, M.1
-
42
-
-
18244390747
-
RET activation and clinicopathologic features in poorly differentiated thyroid tumors
-
Santoro M, et al. RET activation and clinicopathologic features in poorly differentiated thyroid tumors. J Clin Endocrinol Metab. 2002;87(1):370-379.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, Issue.1
, pp. 370-379
-
-
Santoro, M.1
-
43
-
-
63149194964
-
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
-
Pratilas CA, et al. (V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. Proc Natl Acad Sci U S A. 2009;106(11):4519-4524.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.11
, pp. 4519-4524
-
-
Pratilas, C.A.1
-
44
-
-
33947595152
-
N-and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection
-
Fekete CA, et al. N-and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection. EMBO J. 2007;26(6):1602-1614.
-
(2007)
EMBO J
, vol.26
, Issue.6
, pp. 1602-1614
-
-
Fekete, C.A.1
-
45
-
-
34248232601
-
An evidence-based review of poorly differentiated thyroid cancer
-
Sanders EM Jr, LiVolsi VA, Brierley J, Shin J, Randolph GW. An evidence-based review of poorly differentiated thyroid cancer. World J Surg. 2007;31(5):934-945.
-
(2007)
World J Surg
, vol.31
, Issue.5
, pp. 934-945
-
-
Sanders, E.M.1
LiVolsi, V.A.2
Brierley, J.3
Shin, J.4
Randolph, G.W.5
-
47
-
-
53849147531
-
Array-CGH identifies cyclin D1 and UBCH10 amplicons in anaplastic thyroid carcinoma
-
Lee JJ, et al. Array-CGH identifies cyclin D1 and UBCH10 amplicons in anaplastic thyroid carcinoma. Endocr Relat Cancer. 2008;15(3):801-815.
-
(2008)
Endocr Relat Cancer
, vol.15
, Issue.3
, pp. 801-815
-
-
Lee, J.J.1
-
48
-
-
1342280436
-
Chromosomal imbalances associated with anaplastic transformation of follicular thyroid carcinomas
-
Rodrigues RF, Roque L, Rosa-Santos J, Cid O, Soares J. Chromosomal imbalances associated with anaplastic transformation of follicular thyroid carcinomas. Br J Cancer. 2004;90(2):492-496.
-
(2004)
Br J Cancer
, vol.90
, Issue.2
, pp. 492-496
-
-
Rodrigues, R.F.1
Roque, L.2
Rosa-Santos, J.3
Cid, O.4
Soares, J.5
-
49
-
-
0034090225
-
Aberrations of chromosomes 5 and 8 as recurrent cytogenetic events in anaplastic carcinoma of the thyroid as detected by fluorescence in situ hybridisation and comparative genomic hybridisation
-
Wilkens L, et al. Aberrations of chromosomes 5 and 8 as recurrent cytogenetic events in anaplastic carcinoma of the thyroid as detected by fluorescence in situ hybridisation and comparative genomic hybridisation. Virchows Arch. 2000;436(4):312-318.
-
(2000)
Virchows Arch
, vol.436
, Issue.4
, pp. 312-318
-
-
Wilkens, L.1
-
50
-
-
0036841090
-
Genome-wide appraisal of thyroid cancer progression
-
Wreesmann VB, et al. Genome-wide appraisal of thyroid cancer progression. Am J Pathol. 2002;161(5):1549-1556.
-
(2002)
Am J Pathol
, vol.161
, Issue.5
, pp. 1549-1556
-
-
Wreesmann, V.B.1
-
51
-
-
0037364095
-
Anaplastic thyroid cancer: Cytogenetic patterns by comparative genomic hybridization
-
Miura D, et al. Anaplastic thyroid cancer: cytogenetic patterns by comparative genomic hybridization. Thyroid. 2003;13(3):283-290.
-
(2003)
Thyroid
, vol.13
, Issue.3
, pp. 283-290
-
-
Miura, D.1
-
52
-
-
84946232572
-
NF2 loss promotes oncogenic RAS-induced thyroid cancers via YAP-dependent transactivation of RAS proteins sensitizes them to MEK inhibition
-
Garcia-Rendueles ME, et al. NF2 loss promotes oncogenic RAS-induced thyroid cancers via YAP-dependent transactivation of RAS proteins sensitizes them to MEK inhibition. Cancer Discov. 2015;5(11):1178-1193.
-
(2015)
Cancer Discov
, vol.5
, Issue.11
, pp. 1178-1193
-
-
Garcia-Rendueles, M.E.1
-
53
-
-
84865273469
-
Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors
-
Antico Arciuch VG, et al. Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors. Oncotarget. 2011;2(12):1109-1126.
-
(2011)
Oncotarget
, vol.2
, Issue.12
, pp. 1109-1126
-
-
Antico Arciuch, V.G.1
-
54
-
-
84898411721
-
P53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer
-
McFadden DG, et al. p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer. Proc Natl Acad Sci U S A. 2014;111(16):E1600-E1609.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.16
, pp. E1600-E1609
-
-
McFadden, D.G.1
-
55
-
-
84907532336
-
Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression
-
Champa D, Russo MA, Liao XH, Refetoff S, Ghossein RA, Di Cristofano A. Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression. Endocr Relat Cancer. 2014;21(5):755-767.
-
(2014)
Endocr Relat Cancer
, vol.21
, Issue.5
, pp. 755-767
-
-
Champa, D.1
Russo, M.A.2
Liao, X.H.3
Refetoff, S.4
Ghossein, R.A.5
Cristofano, A.D.I.6
-
56
-
-
84903177991
-
Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis
-
Charles RP, Silva J, Iezza G, Phillips WA, McMahon M. Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis. Mol Cancer Res. 2014;12(7):979-986.
-
(2014)
Mol Cancer Res
, vol.12
, Issue.7
, pp. 979-986
-
-
Charles, R.P.1
Silva, J.2
Iezza, G.3
Phillips, W.A.4
McMahon, M.5
-
57
-
-
84866002291
-
The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
-
Cerami E, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2(5):401-404.
-
(2012)
Cancer Discov
, vol.2
, Issue.5
, pp. 401-404
-
-
Cerami, E.1
-
58
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal. 2013;6(269):pl1.
-
(2013)
Sci Signal
, vol.6
, Issue.269
, pp. pl1
-
-
Gao, J.1
-
59
-
-
84881512900
-
Immunohistochemical detection of mutated BRAF V600E supports the clonal origin of BRAF-induced thyroid cancers along the spectrum of disease progression
-
Ghossein RA, Katabi N, Fagin JA. Immunohistochemical detection of mutated BRAF V600E supports the clonal origin of BRAF-induced thyroid cancers along the spectrum of disease progression. J Clin Endocrinol Metab. 2013;98(8):E1414-E1421.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, Issue.8
, pp. E1414-E1421
-
-
Ghossein, R.A.1
Katabi, N.2
Fagin, J.A.3
-
60
-
-
78651271733
-
Integrative genomics viewer
-
Robinson JT, et al. Integrative genomics viewer. Nat Biotechnol. 2011;29(1):24-26.
-
(2011)
Nat Biotechnol
, vol.29
, Issue.1
, pp. 24-26
-
-
Robinson, J.T.1
-
61
-
-
10844290766
-
A model-based background adjustment for oligonucleotide expression arrays
-
Wu Z, Irizarry RA, Gentleman R, Martinez-Murillo F, Spencer F. A model-based background adjustment for oligonucleotide expression arrays. J Am Stat Assoc. 2004;99(468):909-917.
-
(2004)
J Am Stat Assoc
, vol.99
, Issue.468
, pp. 909-917
-
-
Wu, Z.1
Irizarry, R.A.2
Gentleman, R.3
Martinez-Murillo, F.4
Spencer, F.5
-
62
-
-
84863304598
-
-
R Development Core Team.. Vienna, Austria: R Foundation for Statistical Computing
-
R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2015.
-
(2015)
R: A Language and Environment for Statistical Computing
-
-
-
63
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102(43):15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
-
64
-
-
0036081355
-
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
-
Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 2002;30(1):207-210.
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.1
, pp. 207-210
-
-
Edgar, R.1
Domrachev, M.2
Lash, A.E.3
|