Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes

Journal of Cell Biology

Volumn 212, Issue 4, 2016, Pages 439-447

  Hecht, Vivian C ^a,b   Sullivan, Lucas B ^b   Kimmerling, Robert J ^a,b   Kim, Dong Hwee ^c,d,e   Hosios, Aaron M ^b   Stockslager, Max A ^a   Stevens, Mark M ^b   Kang, Joon Ho ^b   Wirtz, Denis ^c,d,e   Vander Heiden, Matthew G ^b,f   Manalis, Scott R ^a,b  

^a Massachusetts Institute of Technology   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d Johns Hopkins University   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; INTERLEUKIN 2; INTERLEUKIN 3; PROTEIN BCL XL; ATG7 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 7; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN BCL X; SIGNAL PEPTIDE;

ADAPTATION; ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CD8+ T LYMPHOCYTE; CELL DEATH; CELL DENSITY; CELL LINE; CELL SURVIVAL; CELL VOLUME; CONTROLLED STUDY; ENERGY EXPENDITURE; LYMPHOCYTE; MEMORY CELL; MOUSE; NONHUMAN; NUTRIENT; NUTRIENT UPTAKE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; T LYMPHOCYTE; ANIMAL; DRUG EFFECT; ENERGY METABOLISM; GENETIC TRANSFECTION; GENETICS; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; PHENOTYPE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR; TRANSGENIC MOUSE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; APOPTOSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 7; BCL-X PROTEIN; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; ENERGY METABOLISM; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-2; INTERLEUKIN-3; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; PHENOTYPE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84959575526     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201506118     Document Type: Article

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