Rhodiola crenulata induces an early estrogenic response and reduces proliferation and tumorsphere formation over time in MCF7 breast cancer cells

Phytomedicine

Volumn 23, Issue 1, 2016, Pages 87-94

  Bassa, Lotfi M ^a,b   Jacobs, Cody ^c   Gregory, Kelly ^a,b   Henchey, Elizabeth ^b,d   Ser Dolansky, Jennifer ^b   Schneider, Sallie S ^a,b,e  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b BAYSTATE HEALTH   (United States)

^c BENNINGTON COLLEGE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Pioneer Valley Life Sciences Institute   (United States)

Author keywords

Continuous treatment; ER+ Breast cancer; In vivo; Phytoestrogens; Rhodiola crenulata; catenin activity

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; PLANT EXTRACT; PROGESTERONE RECEPTOR; RHODIOLA CRENULATA EXTRACT; UNCLASSIFIED DRUG; CTNNB1 PROTEIN, HUMAN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; BREAST EPITHELIUM CELL; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION; HORMONE RESPONSE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LUCIFERASE ASSAY; MCF 7 CELL LINE; MOUSE; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RHODIOLA CRENULATA; TRANSCRIPTION INITIATION; TRANSCRIPTION TERMINATION; WESTERN BLOTTING; 129 MOUSE; ANIMAL; BREAST TUMOR; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; RHODIOLA;

ANIMALS; BETA CATENIN; BREAST NEOPLASMS; CELL PROLIFERATION; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; HUMANS; MCF-7 CELLS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; PLANT EXTRACTS; PLANT ROOTS; RHODIOLA; SPHEROIDS, CELLULAR; TRANSCRIPTIONAL ACTIVATION;

EID: 84959538847     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.11.014     Document Type: Article

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