Clostridium difficile secreted Pro-Pro endopeptidase PPEP-1 (ZMP1/CD2830) modulates adhesion through cleavage of the collagen binding protein CD2831

FEBS Letters

Volumn 589, Issue 24, 2015, Pages 3952-3958

  Hensbergen, Paul J ^a   Klychnikov, Oleg I ^a   Bakker, Dennis ^a   Dragan, Irina ^a   Kelly, Michelle L ^b   Minton, Nigel P ^b   Corver, Jeroen ^a   Kuijper, Ed J ^a   Drijfhout, Jan Wouter ^a   Van Leeuwen, Hans C ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Adhesion; Bacterial virulence; Collagen binding; Motility; Secreted protease

Indexed keywords

ASPARAGINE; CD2831 PROTEIN; COLLAGEN BINDING PROTEIN; COLLAGEN TYPE 1; PPEP 1 PROTEIN; PROTEINASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; HYBRID PROTEIN; MEMBRANE PROTEIN; METALLOPROTEINASE; PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME RELEASE; HAMSTER; HYDROPHOBICITY; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; BACTERIUM ADHERENCE; CHEMICAL PHENOMENA; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; FEMALE; GENE INACTIVATION; GENETICS; MESOCRICETUS; METABOLISM; MUTATION; PATHOGENICITY; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; RAT; SECRETION (PROCESS); VIRULENCE;

AMINO ACID MOTIFS; ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CLOSTRIDIUM DIFFICILE; COLLAGEN TYPE I; FEMALE; GENE KNOCKOUT TECHNIQUES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE PROTEINS; MESOCRICETUS; METALLOENDOPEPTIDASES; MUTATION; PEPTIDE FRAGMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEOLYSIS; RATS; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; VIRULENCE;

EID: 84959505299     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.10.027     Document Type: Article

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