A comprehensive map of CNS transduction by eight recombinant adeno-associated virus serotypes upon cerebrospinal fluid administration in pigs

Molecular Therapy

Volumn 24, Issue 2, 2016, Pages 276-286

  Sorrentino, Nicolina Cristina ^a   Maffia, Veronica ^a   Strollo, Sandra ^a   Cacace, Vincenzo ^a   Romagnoli, Noemi ^b   Manfredi, Anna ^a   Ventrella, Domenico ^b   Dondi, Francesco ^b   Barone, Francesca ^b   Giunti, Massimo ^b   Graham, Anne Renee ^c   Huang, Yan ^c   Kalled, Susan L ^c   Auricchio, Alberto ^a,d   Bacci, Maria Laura ^b   Surace, Enrico Maria ^a,d   Fraldi, Alessandro ^a  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Cubist Pharmaceutical   (United States)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN CORTEX; BRAIN MAPPING; CENTRAL NERVOUS SYSTEM FUNCTION; CENTRAL NERVOUS SYSTEM TRANSDUCTION; CEREBELLUM; CEREBROSPINAL FLUID; CISTERNA MAGNA; CONTROLLED STUDY; FEMALE; GLIA; HIPPOCAMPUS; IMMUNE RESPONSE; MALE; MESENCEPHALON; MOUSE; NONHUMAN; PIG; PROTEIN EXPRESSION; PURKINJE CELL; SEROTYPE; VIRAL GENE DELIVERY SYSTEM; WILD TYPE; ADMINISTRATION AND DOSAGE; ANIMAL; ANTIBODY SPECIFICITY; CENTRAL NERVOUS SYSTEM; DEPENDOPARVOVIRUS; GENE TRANSFER; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; TRANSGENE;

ANIMALS; CENTRAL NERVOUS SYSTEM; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; ORGAN SPECIFICITY; SEROGROUP; SWINE; TRANSDUCTION, GENETIC; TRANSGENES;

EID: 84959503797     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.212     Document Type: Article

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