Pioglitazone-incorporated nanoparticles prevent plaque destabilization and rupture by regulating monocyte/macrophage differentiation in ApoE -/-Mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 3, 2016, Pages 491-500

  Nakashiro, Soichi ^a   Matoba, Tetsuya ^a   Umezu, Ryuta ^a   Koga, Jun Ichiro ^a   Tokutome, Masaki ^a   Katsuki, Shunsuke ^a   Nakano, Kaku ^a   Sunagawa, Kenji ^a   Egashira, Kensuke ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

macrophages; matrix metalloproteinases; nanoparticles; pioglitazone

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; CATHEPSIN; CD147 ANTIGEN; FLUORESCEIN ISOTHIOCYANATE; MATRIX METALLOPROTEINASE; NANOPARTICLE; PIOGLITAZONE; POLYGLACTIN; 2,4 THIAZOLIDINEDIONE DERIVATIVE; AUTACOID; CARDIOVASCULAR AGENT; CYTOKINE; DRUG CARRIER; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTERY RUPTURE; ARTICLE; ATHEROSCLEROTIC PLAQUE; BONE MARROW CELL; BRACHIOCEPHALIC TRUNK; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; LIPID DIET; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; 129 MOUSE; ANIMAL; ATHEROSCLEROSIS; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CHEMISTRY; DEFICIENCY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; INTRAVENOUS DRUG ADMINISTRATION; KNOCKOUT MOUSE; MALE; MEDICINAL CHEMISTRY; METABOLISM; PATHOLOGY; PERITONEUM MACROPHAGE; PHENOTYPE; RUPTURE;

ADMINISTRATION, INTRAVENOUS; ANGIOTENSIN II; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BRACHIOCEPHALIC TRUNK; CARDIOVASCULAR AGENTS; CATHEPSINS; CELL DIFFERENTIATION; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; CYTOKINES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG CARRIERS; INFLAMMATION MEDIATORS; LACTIC ACID; MACROPHAGES, PERITONEAL; MALE; MATRIX METALLOPROTEINASES; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; NANOPARTICLES; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; POLYGLYCOLIC ACID; RUPTURE, SPONTANEOUS; THIAZOLIDINEDIONES;

EID: 84959503473     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.307057     Document Type: Article

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