Nanoparticle-mediated endothelial cell-selective delivery of pitavastatin induces functional collateral arteries (therapeutic arteriogenesis) in a rabbit model of chronic hind limb ischemia

Journal of Vascular Surgery

Volumn 52, Issue 2, 2010, Pages 412-420

  Oda, Shinichiro ^a   Nagahama, Ryoji ^a   Nakano, Kaku ^a   Matoba, Tetsuya ^a   Kubo, Mitsuki ^a   Sunagawa, Kenji ^a   Tominaga, Ryuji ^a   Egashira, Kensuke ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; GLYCERYL TRINITRATE; NANOPARTICLE; PHOSPHATE BUFFERED SALINE; PITAVASTATIN; VASCULOTROPIN RECEPTOR; VATALANIB;

ANGIOGENESIS; ANGIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC HIND LIMB ISCHEMIA; CLINICAL ASSESSMENT; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENDOTHELIUM CELL; EXERCISE; HUMAN; HUMAN CELL; LIMB ISCHEMIA; MALE; NANOTECHNOLOGY; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OXYGEN SATURATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANGIOGENESIS INDUCING AGENTS; ANGIOGENESIS INHIBITORS; ANIMALS; CELLS, CULTURED; CHRONIC DISEASE; COLLATERAL CIRCULATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; ELECTRIC STIMULATION; ENDOTHELIAL CELLS; FEASIBILITY STUDIES; HINDLIMB SUSPENSION; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INJECTIONS, INTRAMUSCULAR; ISCHEMIA; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCLE, SKELETAL; NANOPARTICLES; NEOVASCULARIZATION, PHYSIOLOGIC; OXYGEN; PHTHALAZINES; PROTEIN KINASE INHIBITORS; PYRIDINES; QUINOLINES; RABBITS; REGIONAL BLOOD FLOW; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 77955518648     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2010.03.020     Document Type: Article

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