Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories

PLoS Computational Biology

Volumn 12, Issue 2, 2016, Pages

  Guturu, Harendra ^a,b   Chinchali, Sandeep ^a   Clarke, Shoa L ^b   Bejerano, Gill ^a,b  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EROSION; TRANSCRIPTION;

BINDING-SITES; CARDIAC OUTPUT; GENE-REGULATION; GENETIC COMPONENTS; HEART DISEASE; HUMAN DISEASE; HUMAN GENOMES; MEDICAL HISTORY; PERSONAL GENOMES; TRANSCRIPTION FACTOR BINDING SITES;

BINDING SITES;

SODIUM; TRANSCRIPTION FACTOR; HLA DQ ANTIGEN; HLA-DQB1 ANTIGEN;

ARTICLE; BINDING SITE; CLINICAL ARTICLE; FAMILY HISTORY; FEMALE; GENE MUTATION; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC REGULATION; HEART DISEASE; HEART OUTPUT; HERITABILITY; HUMAN; HUMAN GENOME; HYPERTENSION; MALE; MEDICAL HISTORY; NARCOLEPSY; NEUROPATHY; PHENOTYPE; SODIUM BLOOD LEVEL; BIOLOGICAL MODEL; GENE LINKAGE DISEQUILIBRIUM; GENETICS; GENOMICS; MUTATION; PERSONALIZED MEDICINE; PROCEDURES; STATISTICAL MODEL;

BINDING SITES; GENOME, HUMAN; GENOMICS; HLA-DQ BETA-CHAINS; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MODELS, STATISTICAL; MUTATION; NARCOLEPSY; PRECISION MEDICINE;

EID: 84959473088     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004711     Document Type: Article

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