-
1
-
-
78651349221
-
Biology of human sodium glucose transporters
-
COI: 1:CAS:528:DC%2BC3MXns1Cms7g%3D, PID: 21527736
-
Wright EM, Loo DD, Hirayama BA (2011) Biology of human sodium glucose transporters. Physiol Rev 91:733–794
-
(2011)
Physiol Rev
, vol.91
, pp. 733-794
-
-
Wright, E.M.1
Loo, D.D.2
Hirayama, B.A.3
-
2
-
-
78651348100
-
Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2
-
COI: 1:CAS:528:DC%2BC3MXhsl2qurk%3D, PID: 20980548
-
Hummel CS, Lu C, Loo DD, Hirayama BA, Voss AA, Wright EM (2011) Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. Am J Physiol Cell Physiol 300:C14–C21
-
(2011)
Am J Physiol Cell Physiol
, vol.300
, pp. C14-C21
-
-
Hummel, C.S.1
Lu, C.2
Loo, D.D.3
Hirayama, B.A.4
Voss, A.A.5
Wright, E.M.6
-
3
-
-
78651406659
-
SGLT2 mediates glucose reabsorption in the early proximal tubule
-
COI: 1:CAS:528:DC%2BC3MXhsVChsrY%3D, PID: 20616166
-
Vallon V, Platt KA, Cunard R et al (2011) SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol 22:104–112
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 104-112
-
-
Vallon, V.1
Platt, K.A.2
Cunard, R.3
-
4
-
-
84959549507
-
-
Summary of product characteristics, Available from
-
Boehringer Ingelheim International GmbH (2015). Jardiance (empagliflozin). Summary of product characteristics. Available from www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002677/WC500168592.pdf. Accessed 27 Apr 2015
-
(2015)
Jardiance (empagliflozin)
-
-
-
5
-
-
84959506987
-
-
Summary of product characteristics, Available from
-
AstraZeneca AB (2015). Forxiga (dapagliflozin). Summary of product characteristics. Available from www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002322/WC500136026.pdf. Accessed 27 Apr 2015
-
(2015)
Forxiga (dapagliflozin)
-
-
AstraZeneca, A.B.1
-
6
-
-
84959576591
-
-
Summary of product characteristics, Available from
-
Janssen-Cilag International NV (2015). Invokana (canagliflozin). Summary of product characteristics. Available from www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002649/WC500156456.pdf. Accessed 27 Apr 2015
-
(2015)
Invokana (canagliflozin)
-
-
-
7
-
-
84900458799
-
Ipragliflozin: first global approval
-
COI: 1:CAS:528:DC%2BC2cXmsV2nsbw%3D, PID: 24668021
-
Poole RM, Dungo RT (2014) Ipragliflozin: first global approval. Drugs 74:611–617
-
(2014)
Drugs
, vol.74
, pp. 611-617
-
-
Poole, R.M.1
Dungo, R.T.2
-
8
-
-
84902296808
-
Tofogliflozin: first global approval
-
COI: 1:CAS:528:DC%2BC2cXoslCgsrY%3D, PID: 24848755
-
Poole RM, Prossler JE (2014) Tofogliflozin: first global approval. Drugs 74:939–944
-
(2014)
Drugs
, vol.74
, pp. 939-944
-
-
Poole, R.M.1
Prossler, J.E.2
-
9
-
-
84902240389
-
Luseogliflozin: first global approval
-
COI: 1:CAS:528:DC%2BC2cXoslCgsr8%3D, PID: 24848756
-
Markham A, Elkinson S (2014) Luseogliflozin: first global approval. Drugs 74:945–950
-
(2014)
Drugs
, vol.74
, pp. 945-950
-
-
Markham, A.1
Elkinson, S.2
-
10
-
-
84864146681
-
LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC38XhtVOmtrfP, PID: 22739142
-
Zambrowicz B, Freiman J, Brown PM et al (2012) LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial. Clin Pharmacol Ther 92:158–169
-
(2012)
Clin Pharmacol Ther
, vol.92
, pp. 158-169
-
-
Zambrowicz, B.1
Freiman, J.2
Brown, P.M.3
-
11
-
-
84928381216
-
Dose-ranging efficacy and safety study of ertugliflozin, a sodium-glucose co-transporter 2 inhibitor, in patients with type 2 diabetes on a background of metformin
-
COI: 1:CAS:528:DC%2BC2MXntFGgsLo%3D, PID: 25754396
-
Amin NB, Wang X, Jain SM, Lee DS, Nucci G, Rusnak JM (2015) Dose-ranging efficacy and safety study of ertugliflozin, a sodium-glucose co-transporter 2 inhibitor, in patients with type 2 diabetes on a background of metformin. Diabetes Obes Metab 17:591–598
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 591-598
-
-
Amin, N.B.1
Wang, X.2
Jain, S.M.3
Lee, D.S.4
Nucci, G.5
Rusnak, J.M.6
-
12
-
-
84919489425
-
Randomized efficacy and safety trial of once-daily remogliflozin etabonate for the treatment of type 2 diabetes
-
COI: 1:CAS:528:DC%2BC2cXitVylurvM, PID: 25238025
-
Sykes AP, Kemp GL, Dobbins R et al (2015) Randomized efficacy and safety trial of once-daily remogliflozin etabonate for the treatment of type 2 diabetes. Diabetes Obes Metab 17:98–101
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 98-101
-
-
Sykes, A.P.1
Kemp, G.L.2
Dobbins, R.3
-
13
-
-
84864283226
-
SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects
-
COI: 1:CAS:528:DC%2BC38XhtVOmtLjM, PID: 22310849
-
Ferrannini E, Solini A (2012) SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects. Nat Rev Endocrinol 8:495–502
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 495-502
-
-
Ferrannini, E.1
Solini, A.2
-
14
-
-
84912533839
-
Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BC2cXhsFahtbvE, PID: 24766495
-
Liakos A, Karagiannis T, Athanasiadou E et al (2014) Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and meta-analysis. Diabetes Obes Metab 16:984–993
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 984-993
-
-
Liakos, A.1
Karagiannis, T.2
Athanasiadou, E.3
-
15
-
-
84930580913
-
Update on long-term efficacy and safety of dapagliflozin in patients with type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2MXotVamt78%3D, PID: 25941564
-
Liakos A, Karagiannis T, Bekiari E, Boura P, Tsapas A (2015) Update on long-term efficacy and safety of dapagliflozin in patients with type 2 diabetes mellitus. Ther Adv Endocrinol Metab 6:61–67
-
(2015)
Ther Adv Endocrinol Metab
, vol.6
, pp. 61-67
-
-
Liakos, A.1
Karagiannis, T.2
Bekiari, E.3
Boura, P.4
Tsapas, A.5
-
16
-
-
84901830673
-
Canagliflozin: a review of its use in patients with type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2cXotFOqtLs%3D, PID: 24831734
-
Plosker G (2014) Canagliflozin: a review of its use in patients with type 2 diabetes mellitus. Drugs 74:807–824
-
(2014)
Drugs
, vol.74
, pp. 807-824
-
-
Plosker, G.1
-
17
-
-
84887191925
-
Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia
-
COI: 1:CAS:528:DC%2BC3sXhslCrs7%2FI, PID: 23906374
-
Rosenstock J, Seman LJ, Jelaska A et al (2013) Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia. Diabetes Obes Metab 15:1154–1160
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 1154-1160
-
-
Rosenstock, J.1
Seman, L.J.2
Jelaska, A.3
-
18
-
-
84891851923
-
Long-term safety and efficacy of empagliflozin, sitagliptin, and metformin: an active-controlled, parallel-group, randomized, 78-week open-label extension study in patients with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC3sXhvFaksLrE, PID: 24186878
-
Ferrannini E, Berk A, Hantel S et al (2013) Long-term safety and efficacy of empagliflozin, sitagliptin, and metformin: an active-controlled, parallel-group, randomized, 78-week open-label extension study in patients with type 2 diabetes. Diabetes Care 36:4015–4021
-
(2013)
Diabetes Care
, vol.36
, pp. 4015-4021
-
-
Ferrannini, E.1
Berk, A.2
Hantel, S.3
-
19
-
-
84901455931
-
Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial
-
PID: 24722494
-
Häring HU, Merker L, Seewaldt-Becker E et al (2014) Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care 37:1650–1659
-
(2014)
Diabetes Care
, vol.37
, pp. 1650-1659
-
-
Häring, H.U.1
Merker, L.2
Seewaldt-Becker, E.3
-
20
-
-
84893872877
-
Metabolic response to sodium-glucose co-transporter-2 inhibition in type 2 diabetic patients
-
COI: 1:CAS:528:DC%2BC2cXis1ers7c%3D, PID: 24463454
-
Ferrannini E, Muscelli E, Frascerra S et al (2014) Metabolic response to sodium-glucose co-transporter-2 inhibition in type 2 diabetic patients. J Clin Invest 124:499–508
-
(2014)
J Clin Invest
, vol.124
, pp. 499-508
-
-
Ferrannini, E.1
Muscelli, E.2
Frascerra, S.3
-
21
-
-
84893827104
-
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
-
COI: 1:CAS:528:DC%2BC2cXis1ersL0%3D, PID: 24463448
-
Merovci A, Solis-Herrera C, Daniele G et al (2014) Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest 124:509–514
-
(2014)
J Clin Invest
, vol.124
, pp. 509-514
-
-
Merovci, A.1
Solis-Herrera, C.2
Daniele, G.3
-
22
-
-
82255185902
-
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon
-
COI: 1:CAS:528:DC%2BC38XpvFOitg%3D%3D, PID: 22013018
-
Mutel E, Gautier-Stein A, Abdul-Wahed A et al (2011) Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon. Diabetes 60:3121–3131
-
(2011)
Diabetes
, vol.60
, pp. 3121-3131
-
-
Mutel, E.1
Gautier-Stein, A.2
Abdul-Wahed, A.3
-
23
-
-
84925489733
-
Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
PID: 25583541
-
Inzucchi SE, Bergenstal RM, Buse JB et al (2015) Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 58:429–442
-
(2015)
Diabetologia
, vol.58
, pp. 429-442
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
24
-
-
84908080513
-
The target of metformin in type 2 diabetes
-
PID: 25317875
-
Ferrannini E (2014) The target of metformin in type 2 diabetes. N Engl J Med 371:1547–1548
-
(2014)
N Engl J Med
, vol.371
, pp. 1547-1548
-
-
Ferrannini, E.1
-
25
-
-
33846570905
-
Effect of pioglitazone on the metabolic and hormonal response to a mixed meal in type II diabetes
-
COI: 1:CAS:528:DC%2BD2sXisFyrtLc%3D, PID: 17259945
-
Gastaldelli A, Casolaro A, Pettiti M et al (2007) Effect of pioglitazone on the metabolic and hormonal response to a mixed meal in type II diabetes. Clin Pharmacol Ther 81:205–212
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 205-212
-
-
Gastaldelli, A.1
Casolaro, A.2
Pettiti, M.3
-
26
-
-
0018864615
-
Total body water volumes for adult males and females estimated from simple anthropometric measurements
-
COI: 1:CAS:528:DyaL3cXht1GltL0%3D, PID: 6986753
-
Watson PE, Watson ID, Batt RD (1980) Total body water volumes for adult males and females estimated from simple anthropometric measurements. Am J Clin Nutr 33:27–39
-
(1980)
Am J Clin Nutr
, vol.33
, pp. 27-39
-
-
Watson, P.E.1
Watson, I.D.2
Batt, R.D.3
-
27
-
-
0037866804
-
A circulatory model for calculating non-steady-state glucose fluxes. Validation and comparison with compartmental models
-
Mari A, Stojanovska L, Proietto J, Thorburn AW (2003) A circulatory model for calculating non-steady-state glucose fluxes. Validation and comparison with compartmental models. Comput Methods Prog Biomed 71:269–281
-
(2003)
Comput Methods Prog Biomed
, vol.71
, pp. 269-281
-
-
Mari, A.1
Stojanovska, L.2
Proietto, J.3
Thorburn, A.W.4
-
28
-
-
0023930822
-
The theoretical bases of indirect calorimetry: a review
-
COI: 1:CAS:528:DyaL1cXptFWisA%3D%3D, PID: 3278194
-
Ferrannini E (1988) The theoretical bases of indirect calorimetry: a review. Metabolism 37:287–301
-
(1988)
Metabolism
, vol.37
, pp. 287-301
-
-
Ferrannini, E.1
-
29
-
-
0036889282
-
Meal and oral glucose tests for assessment of β-cell action: modelling analysis in normal subjects
-
COI: 1:CAS:528:DC%2BD38XpslGjtbc%3D, PID: 12388151
-
Mari A, Schmitz O, Gastaldelli A, Oestergaard T, Nyholm B, Ferrannini E (2002) Meal and oral glucose tests for assessment of β-cell action: modelling analysis in normal subjects. Am J Physiol Endocrinol Metab 283:E1159–E1166
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
, pp. E1159-E1166
-
-
Mari, A.1
Schmitz, O.2
Gastaldelli, A.3
Oestergaard, T.4
Nyholm, B.5
Ferrannini, E.6
-
30
-
-
0026504160
-
Estimation of insulin secretion rates from C-peptide levels: comparison of individual and standard kinetic parameters for C-peptide clearance
-
PID: 1551497
-
Van Cauter E, Mestrez F, Sturis J, Polonsky KS (1992) Estimation of insulin secretion rates from C-peptide levels: comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41:368–377
-
(1992)
Diabetes
, vol.41
, pp. 368-377
-
-
Van Cauter, E.1
Mestrez, F.2
Sturis, J.3
Polonsky, K.S.4
-
31
-
-
84907970634
-
Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity?
-
COI: 1:CAS:528:DC%2BC2cXhtlOlt77N, PID: 25172519
-
Wu T, Thazhath SS, Bound MJ, Jones KL, Horowitz M, Rayner CK (2014) Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity? Diabetes Res Clin Pract 106:e3–e6
-
(2014)
Diabetes Res Clin Pract
, vol.106
, pp. e3-e6
-
-
Wu, T.1
Thazhath, S.S.2
Bound, M.J.3
Jones, K.L.4
Horowitz, M.5
Rayner, C.K.6
-
32
-
-
78649908592
-
Addition of metformin to exogenous glucagon-like peptide-1 results in increased serum glucagon-like peptide-1 concentrations and greater glucose lowering in type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC3cXhsFamt7jP, PID: 20152998
-
Cuthbertson J, Patterson S, O’Harte FP, Bell PM (2011) Addition of metformin to exogenous glucagon-like peptide-1 results in increased serum glucagon-like peptide-1 concentrations and greater glucose lowering in type 2 diabetes mellitus. Metabolism 60:52–56
-
(2011)
Metabolism
, vol.60
, pp. 52-56
-
-
Cuthbertson, J.1
Patterson, S.2
O’Harte, F.P.3
Bell, P.M.4
-
33
-
-
84951906012
-
Energy balance following sodium-glucose co-transporter-2 (SGLT2) inhibition
-
PID: 26180105
-
Ferrannini G, Hach T, Crowe S, Sanghvi A, Hall KD, Ferrannini E (2015) Energy balance following sodium-glucose co-transporter-2 (SGLT2) inhibition. Diabetes Care 38:1730–1735
-
(2015)
Diabetes Care
, vol.38
, pp. 1730-1735
-
-
Ferrannini, G.1
Hach, T.2
Crowe, S.3
Sanghvi, A.4
Hall, K.D.5
Ferrannini, E.6
-
34
-
-
84962339296
-
Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition
-
PID: 26078479
-
Peters AL, Buschur EO, Buse JB et al (2015) Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Diabetes Care 38:1687–1693
-
(2015)
Diabetes Care
, vol.38
, pp. 1687-1693
-
-
Peters, A.L.1
Buschur, E.O.2
Buse, J.B.3
|