Synergistic Effect of Cold Atmospheric Plasma and Drug Loaded Core-shell Nanoparticles on Inhibiting Breast Cancer Cell Growth

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Zhu, Wei ^a   Lee, Se Jun ^a   Castro, Nathan J ^a   Yan, Dayun ^a   Keidar, Michael ^a   Zhang, Lijie Grace ^a,b  

^a The George Washington University   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG CARRIER; LACTIC ACID; NANOPARTICLE; PLASMA GAS; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

BREAST NEOPLASMS; CHEMISTRY; HUMAN; MULTIMODALITY CANCER THERAPY; NEOPLASM METASTASIS; PATHOLOGY; PHARMACOLOGY; PLASMA GAS; SYNTHESIS; THERAPEUTIC USE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; DRUG CARRIERS; HUMANS; LACTIC ACID; NANOPARTICLES; NEOPLASM METASTASIS; PLASMA GASES; POLYGLYCOLIC ACID;

EID: 84959431426     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21974     Document Type: Article

References (43)

1. Passant, H. & Borley, A. Adjuvant treatment for breast cancer. Surgery (United Kingdom) 31, 37-40 (2013).
2. Lin, Y., Li, Y. & Ooi, C. P. 5-Fluorouracil encapsulated HA/PLGA composite microspheres for cancer therapy. Journal of Materials Science: Materials in Medicine 23, 2453-2460 (2012).
3. Cameron, D. A., Gabra, H. & Leonard, R. C. F. Continuous 5-fluorouracil in the treatment of breast cancer. British Journal of Cancer 70, 120-124 (1994).
4. Diasio, R. B. & Harris, B. E. Clinical pharmacology of 5-fluorouracil. Clinical Pharmacokinetics 16, 215-237 (1989).
5. Davis, M. E., Chen, Z. & Shin, D. M. Nanoparticle therapeutics: An emerging treatment modality for cancer. Nature Reviews Drug Discovery 7, 771-782 (2008).
6. Ge, J., Neofytou, E., Lei, J. D., Beygui, R. E. & Zare, R. N. Protein-Polymer Hybrid Nanoparticles for Drug Delivery. Small 8, 3573-3578 (2012).
7. Bushman, J. et al. Functionalized nanospheres for targeted delivery of paclitaxel. Journal of Controlled Release 171, 315-321 (2013).
8. Matsumura, Y. & Kataoka, K. Preclinical and clinical studies of anticancer agent-incorporating polymer micelles. Cancer Science 100, 572-579 (2009).
9. Arya, N., Chakraborty, S., Dube, N. & Katti, D. S. Electrospraying: A Facile Technique for Synthesis of Chitosan-Based Micro/Nanospheres for Drug Delivery Applications. Journal of biomedical materials research part b-applied biomaterials 88B, 17-31 (2009).
10. Yang, P., Gai, S. & Lin, J. Functionalized mesoporous silica materials for controlled drug delivery. Chemical Society Reviews 41, 3679-3698 (2012).
11. Ratovitski, E. A. et al. Anti-Cancer Therapies of 21st Century: Novel Approach to Treat Human Cancers Using Cold Atmospheric Plasma. Plasma Processes and Polymers 11, 1128-1137 (2014).
12. Volotskova, O., Hawley, T. S., Stepp, M. A. & Keidar, M. Targeting the cancer cell cycle by cold atmospheric plasma. Scientific reports 2, 636 (2012).
13. Arndt, S. et al. Cold Atmospheric Plasma (CAP) Changes Gene Expression of Key Molecules of the Wound Healing Machinery and Improves Wound Healing In Vitro and In Vivo: e79325. PLoS ONE 8 (2013).
14. Wang, D. et al. The cold and atmospheric-pressure air surface barrier discharge plasma for large-area sterilization applications. Applied Physics Letters 98, 161501-161501-161503 (2011).
15. Wang, M. et al. Cold Atmospheric Plasma for Selectively Ablating Metastatic Breast Cancer Cells. Plos One 8, e73741 (2013).
16. Keidar, M. et al. Cold atmospheric plasma in cancer therapy. Physics of Plasmas 20, 057101-057101-057108 (2013).
17. Cheng, X. et al. The effect of tuning cold plasma composition on glioblastoma cell viability. PloS one 9, e98652 (2014).
18. Kalghatgi, S. et al. Effects of non-thermal plasma on mammalian cells. PloS one 6, e16270 (2011).
19. Fridman, G. et al. Applied plasma medicine. Plasma Processes and Polymers 5, 503-533 (2008).
20. Graves, D. B. Reactive Species from Cold Atmospheric Plasma: Implications for Cancer Therapy. Plasma Processes and Polymers (2014).
21. Yan, D. Y. et al. Controlling plasma stimulated media in cancer treatment application. Applied Physics Letters 105, 224101 (2014).
22. Cheng, X. Q. et al. Synergistic effect of gold nanoparticles and cold plasma on glioblastoma cancer therapy. Journal of Physics D-Applied Physics 47 (2014).
23. Kim, G. C. et al. Air plasma coupled with antibody-conjugated nanoparticles: A new weapon against cancer. Journal of Physics D: Applied Physics 42, 032005 (2009).
24. Kong, M. G., Keidar, M. & Ostrikov, K. Plasmas meet nanoparticles - where synergies can advance the frontier of medicine. Journal of Physics D: Applied Physics 44, 174018 (2011).
25. Iyer, S., Gaikwad, R. M., Subba Rao, V., Woodworth, C. D. & Sokolov, I. Atomic force microscopy detects differences in the surface brush of normal and cancerous cells. Nat Nano 4, 389-393 (2009).
26. Kucerova, L., Altanerova, V., Matuskova, M., Tyciakova, S. & Altaner, C. Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Research 67, 6304-6313 (2007).
27. Yu, S.-L. et al. Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells. Oncology reports 30, 1293-1300 (2013).
28. Sridhar, R. et al. Electrosprayed nanoparticles and electrospun nanofibers based on natural materials: applications in tissue regeneration, drug delivery and pharmaceuticals. Chemical Society reviews 44, 790-814 (2015).
29. Jaworek, A. Micro-and nanoparticle production by electrospraying. Powder Technology 176, 18-35 (2007).
30. Xie, J., Lim, L. K., Phua, Y., Hua, J. & Wang, C.-H. Electrohydrodynamic atomization for biodegradable polymeric particle production. Journal of Colloid And Interface Science 302, 103-112 (2006).
31. Mu, L. & Feng, S. S. A novel controlled release formulation for the anticancer drug paclitaxel (TaxolR ): PLGA nanoparticles containing vitamin E TPGS. Journal of Controlled Release 86, 33-48 (2003).
32. Lee, Y.-H., Mei, F., Bai, M.-Y., Zhao, S. & Chen, D.-R. Release profile characteristics of biodegradable-polymer-coated drug particles fabricated by dual-capillary electrospray. Journal of Controlled Release 145, 58-65 (2010).
33. Panyam, J. et al. Polymer degradation and in vitro release of A model protein from poly(d,l-lactide-co-glycolide) nano-and microparticles. Journal of Controlled Release 92, 173-187 (2003).
34. Danhier, F. et al. PLGA-based nanoparticles: An overview of biomedical applications. Journal of Controlled Release 161, 505-522 (2012).
35. Mura, S. et al. Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells. International journal of nanomedicine 6, 2591-2605 (2011).
36. Hu, G. et al. MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer. Cancer Cell 15, 9-20 (2009).
37. Hirst, D. & Robson, T. Targeting nitric oxide for cancer therapy. Journal of Pharmacy and Pharmacology 59, 3-13 (2007).
38. Cheng, C. J., Tietjen, G. T., Saucier-Sawyer, J. K. & Saltzman, W. M. A holistic approach to targeting disease with polymeric nanoparticles. Nature Reviews Drug Discovery (2015).
39. Morent, R., De Geyter, N., Desmet, T., Dubruel, P. & Leys, C. Plasma surface modification of biodegradable polymers: A review. Plasma Processes and Polymers 8, 171-190 (2011).
40. Yan, W., Han, Z. J., Phung, B. T. & Ostrikov, K. Silica Nanoparticles Treated by Cold Atmospheric-Pressure Plasmas Improve the Dielectric Performance of Organic-Inorganic Nanocomposites. Acs Applied Materials & Interfaces 4, 2637-2642 (2012).
41. Hasirci, N., Endogan, T., Vardar, E., Kiziltay, A. & Hasirci, V. Effect of oxygen plasma on surface properties and biocompatibility of PLGA films. Surface and Interface Analysis 42, 486-491 (2010).
42. Lee, S. J., Lee, H. B., Lee, Y. M. & Khang, G. The effect of surface wettability on induction and growth of neurites from the PC-12 cell on A polymer surface. Journal of Colloid And Interface Science 259, 228-235 (2003).
43. Recek, N. et al. Effect of Cold Plasma on Glial Cell Morphology Studied by Atomic Force Microscopy: e0119111. PLoS One 10 (2015).