Mangiferin suppressed advanced glycation end products (AGEs) through NF -κ B deactivation and displayed anti-inflammatory effects in streptozotocin and high fat diet-diabetic cardiomyopathy rats

Canadian Journal of Physiology and Pharmacology

Volumn 94, Issue 3, 2015, Pages 332-340

  Hou, Jun ^a,b   Zheng, Dezhi ^c   Fung, Gabriel ^b   Deng, Haoyu ^b   Chen, Lin ^d   Liang, Jiali ^c   Jiang, Yan ^a   Hu, Yonghe ^a  

^a CHENGDU MILITARY GENERAL HOSPITAL   (China)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c JINAN MILITARY GENERAL HOSPITAL   (China)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Advanced glycation end products; Diabetic cardiomyopathy; Inflammatory cytokines; Mangiferin; NF B

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ANTIINFLAMMATORY AGENT; CREATINE KINASE MB; CYTOKINE; HYDROETHIDINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; MANGIFERIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; STREPTOZOCIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ADVANCED GLYCATION END PRODUCT RECEPTOR; XANTHONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ANALYSIS; GENE EXPRESSION; HEART LEFT VENTRICLE MUSCLE; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HEART PROTECTION; LIPID DIET; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STAINING; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; CARDIAC MUSCLE; CHEMICALLY INDUCED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DRUG EFFECTS; METABOLISM; OXIDATIVE STRESS; SPRAGUE DAWLEY RAT;

ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR; ANIMALS; ANTI-INFLAMMATORY AGENTS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DIET, HIGH-FAT; GLYCOSYLATION END PRODUCTS, ADVANCED; INTERLEUKIN-1BETA; MALE; MYOCARDIUM; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STREPTOZOCIN; XANTHONES;

EID: 84959354256     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2015-0073     Document Type: Article

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