CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells

Cancer Letters

Volumn 374, Issue 1, 2016, Pages 44-53

  Suyama, Kumi ^a   Onishi, Hideya ^a   Imaizumi, Akira ^b   Shinkai, Kentaro ^a   Umebayashi, Masayo ^c   Kubo, Makoto ^a   Mizuuchi, Yusuke ^a   Oda, Yoshinao ^a   Tanaka, Masao ^a   Nakamura, Masafumi ^a   Katano, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Shukoukai Inc   (Japan)

^c Fukuoka General Cancer Clinic   (Japan)

Author keywords

Breast cancer; Cancer stem cell; CD24; Sonic hedgehog; STAT1

Indexed keywords

CD24 ANTIGEN; GELATINASE A; SMALL INTERFERING RNA; SONIC HEDGEHOG PROTEIN; STAT1 PROTEIN; CD24 PROTEIN, HUMAN; SHH PROTEIN, HUMAN; STAT1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER CELL LINE; CANCER GROWTH; CARCINOGENICITY; CD24 GENE; CELL ANCHORAGE; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE TRANSFER; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR INVASION; TUMOR VOLUME; ANIMAL; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; DRUG SCREENING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HUMAN; MCF 7 CELL LINE; METABOLISM; NONOBESE DIABETIC MOUSE; PHENOTYPE; SCID MOUSE; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD24; BREAST NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; HEDGEHOG PROTEINS; HUMANS; MCF-7 CELLS; MICE; MICE, INBRED NOD; MICE, SCID; PHENOTYPE; RNA, SMALL INTERFERING; STAT1 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84959324589     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.12.013     Document Type: Article

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