Effect of Vitamin D supplementation on measures of arterial stiffness: A systematic review and meta-analysis of randomized controlled trials

Clinical Endocrinology

Volumn 84, Issue 5, 2016, Pages 645-657

  Rodríguez, Alexander J ^a   Scott, David ^b   Srikanth, Velandai ^a   Ebeling, Peter ^b  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D; VITAMIN;

ARTERIAL STIFFNESS; ARTICLE; AUGMENTATION INDEX; COMPUTER PROGRAM; CONFIDENCE INTERVAL; FOLLOW UP; HUMAN; META ANALYSIS; PRIORITY JOURNAL; PULSE WAVE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RATING SCALE; SAMPLE SIZE; SYSTEMATIC REVIEW; VITAMIN SUPPLEMENTATION; DIETARY SUPPLEMENT; DRUG EFFECTS; TREATMENT OUTCOME;

DIETARY SUPPLEMENTS; FOLLOW-UP STUDIES; HUMANS; PULSE WAVE ANALYSIS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME; VASCULAR STIFFNESS; VITAMIN D; VITAMINS;

EID: 84959295517     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.13031     Document Type: Article

References (51)

1. Li, Y.C., Kong, J., Wei, M., et al,. (2002) 1,25-DihydroxyVitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. The Journal of Clinical Investigation, 110, 229-238.
2. Norman, A.W., Frankel, J.B., Heldt, A.M., et al,. (1980) Vitamin D deficiency inhibits pancreatic secretion of insulin. Science (New York, NY), 209, 823-825.
3. Almerighi, C., Sinistro, A., Cavazza, A., et al,. (2009) 1Alpha,25-dihydroxyVitamin D3 inhibits CD40L-induced pro-inflammatory and immunomodulatory activity in human monocytes. Cytokine, 45, 190-197.
4. Rosen, C.J., Adams, J.S., Bikle, D.D., et al,. (2012) The nonskeletal effects of Vitamin D: an Endocrine Society scientific statement. Endocrine Reviews, 33, 456-492.
5. Melamed, M.L., Muntner, P., Michos, E.D., et al,. (2008) Serum 25-hydroxyVitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004. Arteriosclerosis, Thrombosis, and Vascular Biology, 28, 1179-1185.
6. London, G.M., Guerin, A.P., Verbeke, F.H., et al,. (2007) Mineral metabolism and arterial functions in end-stage renal disease: potential role of 25-hydroxyVitamin D deficiency. Journal of the American Society of Nephrology: JASN, 18, 613-620.
7. Wang, Y.Q., et al,. (2015) Low bone mineral density is associated with increased arterial stiffness in participants of a health records based study. J Thorac Dis, 7, 790-8.
8. Brunner, E.J., et al,. (2011) Arterial stiffness, physical function, and functional limitation: the Whitehall II Study. Hypertension, 57, 1003-9.
9. Kidher, E., et al,. (2014) High aortic pulse wave velocity is associated with poor quality of life in surgical aortic valve stenosis patients. Interact Cardiovasc Thorac Surg, 19, 189-97.
10. Hametner, B., Wassertheurer, S., Kropf, J., et al,. (2013) Oscillometric estimation of aortic pulse wave velocity: comparison with intra-aortic catheter measurements. Blood Pressure Monitoring, 18, 173-176.
11. Laurent, S., Cockcroft, J., Van Bortel, L., et al,. (2006) Expert consensus document on arterial stiffness: methodological issues and clinical applications. European Heart Journal, 27, 2588-2605.
12. Andrade, J., Er, L., Ignaszewski, A., et al,. (2008) Exploration of association of 1,25-OH2D3 with augmentation index, a composite measure of arterial stiffness. Clinical Journal of the American Society of Nephrology: CJASN, 3, 1800-1806.
13. Moher, D., Liberati, A., Tetzlaff, J., et al,. (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Journal of Clinical Epidemiology, 62, 1006-1012.
14. Jadad, A.R., Moore, R.A., Carroll, D., et al,. (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled Clinical Trials, 17, 1-12.
15. Dong, Y., Stallmann-Jorgensen, I.S., Pollock, N.K., et al,. (2010) A 16-week randomized clinical trial of 2000 international units daily Vitamin D3 supplementation in black youth: 25-hydroxyVitamin D, adiposity, and arterial stiffness. Journal of Clinical Endocrinology and Metabolism, 95, 4584-4591.
16. McGreevy, C., Barry, M., Bennett, K., et al,. (2013) The effect of Vitamin D replacement on arterial stiffness in an elderly community based population. Irish Journal of Medical Science, 182, S234-S235.
17. Gepner, A.D., Ramamurthy, R., Krueger, D.C., et al,. (2012) A prospective randomized controlled trial of the effects of Vitamin D supplementation on cardiovascular disease risk. PLoS One, 7, e36617.
18. Ryu, O.H., Chung, W., Lee, S., et al,. (2014) The effect of high-dose Vitamin D supplementation on insulin resistance and arterial stiffness in patients with type 2 diabetes. Korean Journal of Internal Medicine, 29, 620-629.
19. Higgins, J.P., &, Thompson, S.G., (2002) Quantifying heterogeneity in a meta-analysis. Statistics in Medicine, 21, 1539-1558.
20. Breslavsky, A., Frand, J., Matas, Z., et al,. (2013) Effect of high doses of Vitamin D on arterial properties, adiponectin, leptin and glucose homeostasis in type 2 diabetic patients. Clinical Nutrition, 32, 970-975.
21. Larsen, T., Mose, F.H., Bech, J.N., et al,. (2012) Effect of cholecalciferol supplementation during winter months in patients with hypertension: a randomized, placebo-controlled trial. American Journal of Hypertension, 25, 1215-1222.
22. Dreyer, G., Tucker, A.T., Harwood, S.M., et al,. (2014) Ergocalciferol and microcirculatory function in chronic kidney disease and concomitant vitamin d deficiency: an exploratory, double blind, randomised controlled trial. PLoS One, 9, e99461.
23. Garg, G., Kachhawa, G., Ramot, R., et al,. (2015) Effect of Vitamin D supplementation on insulin kinetics and cardiovascular risk factors in polycystic ovarian syndrome: a pilot study. Endocrinology Connect, 4, 108-116.
24. Hewitt, N., O'Connor, A., O'Shaughnessy, D., et al,. (2012) Effects of cholecalciferol on laboratory, functional, vascular and quality of life outcomes in patients on dialysis; a randomised controlled trial. Bone, 50, S168.
25. Marckmann, P., Agerskov, H., Thineshkumar, S., et al,. (2012) Randomized controlled trial of cholecalciferol supplementation in chronic kidney disease patients with hypovitaminosis D. Nephrology, Dialysis, Transplantation, 27, 3523-3531.
26. Martins, D., Meng, Y.X., Tareen, N., et al,. (2014) The effect of short term vitamin d supplementation on the inflammatory and oxidative mediators of arterial stiffness. Health (Irvine Calif), 6, 1503-1511.
27. Mose, F.H., Vase, H., Larsen, T., et al,. (2014) Cardiovascular effects of cholecalciferol treatment in dialysis patients-a randomized controlled trial. BMC Nephrology, 15, 50.
28. Pilz, S., Gaksch, M., Kienreich, K., et al,. (2015) Effects of vitamin d on blood pressure and cardiovascular risk factors: a randomized controlled trial. Hypertension, 65, 1195-1201.
29. Stricker, H., Tosi Bianda, F., Guidicelli-Nicolosi, S., et al,. (2012) Effect of a single, oral, high-dose Vitamin D supplementation on endothelial function in patients with peripheral arterial disease: a randomised controlled pilot study. European Journal of Vascular and Endovascular Surgery, 44, 307-312.
30. Witham, M.D., Adams, F., McSwiggan, S., et al,. (2015) Effect of intermittent Vitamin D3 on vascular function and symptoms in chronic fatigue syndrome-a randomised controlled trial. Nutrition, Metabolism and Cardiovascular Diseases, 25, 287-294.
31. Witham, M.D., Price, R.J.G., Struthers, A.D., et al,. (2013) Cholecalciferol treatment to reduce blood pressure in older patients with isolated systolic hypertension the VitDISH randomized controlled trial. JAMA Internal Medicine, 173, 1672-1679.
32. Yiu, Y.F., Yiu, K.H., Siu, C.W., et al,. (2013) Randomized controlled trial of Vitamin D supplement on endothelial function in patients with type 2 diabetes. Atherosclerosis, 227, 140-146.
33. Gepner, A.D., Haller, I.V., Krueger, D.C., et al,. (2015) A randomized controlled trial of the effects of Vitamin D supplementation on arterial stiffness and aortic blood pressure in Native American women. Atherosclerosis, 240, 526-528.
34. Al Mheid, I., Patel, R., Murrow, J., et al,. (2011) Vitamin D status is associated with arterial stiffness and vascular dysfunction in healthy humans. Journal of the American College of Cardiology, 58, 186-192.
35. Giallauria, F., Milaneschi, Y., Tanaka, T., et al,. (2012) Arterial stiffness and Vitamin D levels: the Baltimore longitudinal study of aging. The Journal of Clinical Endocrinology and Metabolism, 97, 3717-3723.
36. Zhang, Y., Leung, D.Y., Richers, B.N., et al,. (2012) Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. Journal of Immunology (Baltimore, Md: 1950), 188, 2127-2135.
37. Talmor, Y., Golan, E., Benchetrit, S., et al,. (2008) Calcitriol blunts the deleterious impact of advanced glycation end products on endothelial cells 2008-05-01 00:00:00. F1059-F64 p.
38. Bukoski, R.D., DeWan, P., &, McCarron, D.A., (1989) 1,25 (OH)2 Vitamin D3 modifies growth and contractile function of vascular smooth muscle of spontaneously hypertensive rats. American Journal of Hypertension, 2, 553-556.
39. Raymond, M.A., Desormeaux, A., Labelle, A., et al,. (2005) Endothelial stress induces the release of Vitamin D-binding protein, a novel growth factor. Biochemical and Biophysical Research Communications, 338, 1374-1382.
40. Lewis, R.D., &, Laing, E.M., (2015) Conflicting reports on Vitamin D supplementation: evidence from randomized controlled trials. Molecular and Cellular Endocrinology, 410, 11-18.
41. Nigil Haroon, N., Anton, A., John, J., et al,. (2015) Effect of Vitamin D supplementation on glycemic control in patients with type 2 diabetes: a systematic review of interventional studies. Journal of Diabetes and Metabolic Disorders, 14, 3.
42. Sanders, K.M., Nicholson, G.C., &, Ebeling, P.R., (2013) Is high dose Vitamin D harmful? Calcified Tissue International, 92, 191-206.
43. Wilson, R.T., Bortner, J.D. Jr, Roff, A., et al,. (2015) Genetic and environmental influences on plasma Vitamin D binding protein concentrations. Translational Research: the Journal of Laboratory and Clinical Medicine, 165, 667-676.
44. van Ballegooijen, A.J., Gansevoort, R.T., Lambers-Heerspink, H.J., et al,. (2015) Plasma 1,25-DihydroxyVitamin D and the Risk of Developing Hypertension: the Prevention of Renal and Vascular End-Stage Disease Study. Hypertension, 66, 563-570.
45. Wortsman, J., Matsuoka, L.Y., Chen, T.C., et al,. (2000) Decreased bioavailability of Vitamin D in obesity. The American Journal of Clinical Nutrition, 72, 690-693.
46. Afzal, S., Brondum-Jacobsen, P., Bojesen, S.E., et al,. (2014) Vitamin D concentration, obesity, and risk of diabetes: a mendelian randomisation study. The Lancet Diabetes & Endocrinology, 2, 298-306.
47. Autier, P., Boniol, M., Pizot, C., et al,. (2014) Vitamin D status and ill health: a systematic review. The Lancet Diabetes & Endocrinology, 2, 76-89.
48. Van den Berghe, G., Van Roosbroeck, D., Vanhove, P., et al,. (2003) Bone turnover in prolonged critical illness: effect of Vitamin D. The Journal of Clinical Endocrinology and Metabolism, 88, 4623-4632.
49. Scott, D., Ebeling, P.R., Sanders, K.M., et al,. (2015) Vitamin D and physical activity status: associations with five-year changes in body composition and muscle function in community-dwelling older adults. The Journal of Clinical Endocrinology and Metabolism, 100, 670-678.
50. Tillin, T., Chambers, J., Malik, I., et al,. (2007) Measurement of pulse wave velocity: site matters. Journal of Hypertension, 25, 383-389.
51. Norman, P.E., &, Powell, J.T., (2014) Vitamin D and cardiovascular disease. Circulation Research, 114, 379-393.