Common polymorphisms that affect folate transport or metabolism modify the effect of the MTHFR 677C > T polymorphism on folate status

Journal of Nutrition

Volumn 146, Issue 1, 2016, Pages 1-8

  Bueno, Olalla ^a,b   Molloy, Anne M ^c   Fernandez Ballart, Joan D ^a,b   García Minguillán, Carlos J ^a,b   Ceruelo, Santiago ^b,d   Ríos, Lídia ^d   Ueland, Per M ^e   Meyer, Klaus ^f   Murphy, Michelle M ^a,b  

^a INSTITUT D INVESTIGACIÓ SANITÀRIA PERE VIRGILI IISPV   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d Primary Health Care Center   (Spain)

^e UNIVERSITY OF BERGEN   (Norway)

^f BEVITAL AS   (Norway)

Author keywords

Homocysteine; MTHFD1 105C > T; MTHFD1 1958G > A; MTHFR 677C > T; MTRR 524C > T; MTRR 66A > G; Plasma folate; population study; Red cell folate; SLC19A1 80G > A

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE DEHYDROGENASE 5,10 METHYLENETETRAHYDROFOLATE CYCLOHYDROLASE 10 FORMYLTETRAHYDROFOLATE SYNTHETASE; 5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DIHYDROFOLATE REDUCTASE; FOLIC ACID; FORMATE TETRAHYDROFOLATE LIGASE; HOMOCYSTEINE; METHIONINE TRANSFERASE REDUCTASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CROSS-SECTIONAL STUDY; DNA POLYMORPHISM; ENZYME POLYMORPHISM; ERYTHROCYTE; FEMALE; FOLIC ACID BLOOD LEVEL; FOLIC ACID DEFICIENCY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HOMOZYGOTE; HUMAN; INDEL MUTATION; MAJOR CLINICAL STUDY; MALE; ADOLESCENT; ALLELE; BLOOD; DIET RESTRICTION; GENETIC POLYMORPHISM; GENETICS; MIDDLE AGED; PROPORTIONAL HAZARDS MODEL; SPAIN; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALLELES; CROSS-SECTIONAL STUDIES; FASTING; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE FREQUENCY; GENOTYPE; HOMOCYSTEINE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; POLYMORPHISM, GENETIC; PROPORTIONAL HAZARDS MODELS; SPAIN; YOUNG ADULT;

EID: 84959273450     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.115.223685     Document Type: Article

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