Cell competition drives the formation of metastatic tumors in a drosophila model of epithelial tumor formation

Current Biology

Volumn 26, Issue 4, 2016, Pages 419-427

  Eichenlaub, Teresa ^a   Cohen, Stephen M ^a,b   Herranz, Héctor ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; EGFR PROTEIN, DROSOPHILA; EPIDERMAL GROWTH FACTOR RECEPTOR; MICRORNA; RECEPTOR;

ANIMAL; CARCINOGENESIS; CELL PROLIFERATION; CELL TRANSFORMATION; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; NEOPLASMS, GLANDULAR AND EPITHELIAL; PATHOPHYSIOLOGY;

ANIMALS; CARCINOGENESIS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HUMANS; MICRORNAS; NEOPLASMS, GLANDULAR AND EPITHELIAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, INVERTEBRATE PEPTIDE;

EID: 84959271116     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2015.12.042     Document Type: Article

References (44)

1. P. Simpson Parameters of cell competition in the compartments of the wing disc of Drosophila Dev. Biol. 69 1979 182 193
2. P. Simpson, and G. Morata Differential mitotic rates and patterns of growth in compartments in the Drosophila wing Dev. Biol. 85 1981 299 308
3. M.M. Merino, C. Rhiner, J.M. Lopez-Gay, D. Buechel, B. Hauert, and E. Moreno Elimination of unfit cells maintains tissue health and prolongs lifespan Cell 160 2015 461 476
4. S.N. Meyer, M. Amoyel, C. Bergantiños, C. de la Cova, C. Schertel, K. Basler, and L.A. Johnston An ancient defense system eliminates unfit cells from developing tissues during cell competition Science 346 2014 1258236
5. E. Moreno, K. Basler, and G. Morata Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development Nature 416 2002 755 759
6. J.P. Vincent, G. Kolahgar, M. Gagliardi, and E. Piddini Steep differences in wingless signaling trigger Myc-independent competitive cell interactions Dev. Cell 21 2011 366 374
7. C. de la Cova, M. Abril, P. Bellosta, P. Gallant, and L.A. Johnston Drosophila myc regulates organ size by inducing cell competition Cell 117 2004 107 116
8. E. Moreno, and K. Basler dMyc transforms cells into super-competitors Cell 117 2004 117 129
9. C. Clavería, G. Giovinazzo, R. Sierra, and M. Torres Myc-driven endogenous cell competition in the early mammalian embryo Nature 500 2013 39 44
10. Y. Tamori, C.U. Bialucha, A.G. Tian, M. Kajita, Y.C. Huang, M. Norman, N. Harrison, J. Poulton, K. Ivanovitch, L. Disch, and et al. Involvement of Lgl and Mahjong/VprBP in cell competition PLoS Biol. 8 2010 e1000422
11. W. Li, and N.E. Baker Engulfment is required for cell competition Cell 129 2007 1215 1225
12. Q. Sun, T. Luo, Y. Ren, O. Florey, S. Shirasawa, T. Sasazuki, D.N. Robinson, and M. Overholtzer Competition between human cells by entosis Cell Res. 24 2014 1299 1310
13. R. Levayer, and E. Moreno Mechanisms of cell competition: themes and variations J. Cell Biol. 200 2013 689 698
14. L.A. Johnston Socializing with MYC: cell competition in development and as a model for premalignant cancer Cold Spring Harb. Perspect. Med. 4 2014 a014274
15. L. Baillon, and K. Basler Reflections on cell competition Semin. Cell Dev. Biol. 32 2014 137 144
16. J.G. Paez, P.A. Jänne, J.C. Lee, S. Tracy, H. Greulich, S. Gabriel, P. Herman, F.J. Kaye, N. Lindeman, T.J. Boggon, and et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 2004 1497 1500
17. M. Sibilia, R. Kroismayr, B.M. Lichtenberger, A. Natarajan, M. Hecking, and M. Holcmann The epidermal growth factor receptor: from development to tumorigenesis Differentiation 75 2007 770 787
18. C. Kandoth, M.D. McLellan, F. Vandin, K. Ye, B. Niu, C. Lu, M. Xie, Q. Zhang, J.F. McMichael, M.A. Wyczalkowski, and et al. Mutational landscape and significance across 12 major cancer types Nature 502 2013 333 339
19. H. Herranz, X. Hong, N.T. Hung, P.M. Voorhoeve, and S.M. Cohen Oncogenic cooperation between SOCS family proteins and EGFR identified using a Drosophila epithelial transformation model Genes Dev. 26 2012 1602 1611
20. H. Herranz, R. Weng, and S.M. Cohen Crosstalk between epithelial and mesenchymal tissues in tumorigenesis and imaginal disc development Curr. Biol. 24 2014 1476 1484
21. F.N. Lolo, S. Casas-Tintó, and E. Moreno Cell competition time line: winners kill losers, which are extruded and engulfed by hemocytes Cell Rep. 2 2012 526 539
22. F. Pan, R.L. Malmberg, and M. Momany Analysis of septins across kingdoms reveals orthology and new motifs BMC Evol. Biol. 7 2007 103
23. T.P. Neufeld, and G.M. Rubin The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins Cell 77 1994 371 379
24. N. Founounou, N. Loyer, and R. Le Borgne Septins regulate the contractility of the actomyosin ring to enable adherens junction remodeling during cytokinesis of epithelial cells Dev. Cell 24 2013 242 255
25. M. Kinoshita, S. Kumar, A. Mizoguchi, C. Ide, A. Kinoshita, T. Haraguchi, Y. Hiraoka, and M. Noda Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures Genes Dev. 11 1997 1535 1547
26. E. Moreno Is cell competition relevant to cancer? Nat. Rev. Cancer 8 2008 141 147
27. N.E. Baker, and W. Li Cell competition and its possible relation to cancer Cancer Res. 68 2008 5505 5507
28. L. Wagstaff, G. Kolahgar, and E. Piddini Competitive cell interactions in cancer: a cellular tug of war Trends Cell Biol. 23 2013 160 167
29. T. Fujiwara, M. Bandi, M. Nitta, E.V. Ivanova, R.T. Bronson, and D. Pellman Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells Nature 437 2005 1043 1047
30. T. Davoli, E.L. Denchi, and T. de Lange Persistent telomere damage induces bypass of mitosis and tetraploidy Cell 141 2010 81 93
31. T. Davoli, and T. de Lange Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells Cancer Cell 21 2012 765 776
32. J. Morante, D.M. Vallejo, C. Desplan, and M. Dominguez Conserved miR-8/miR-200 defines a glial niche that controls neuroepithelial expansion and neuroblast transition Dev. Cell 27 2013 174 187
33. D.M. Vallejo, E. Caparros, and M. Dominguez Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells EMBO J. 30 2011 756 769
34. X. Feng, Z. Wang, R. Fillmore, and Y. Xi MiR-200, a new star miRNA in human cancer Cancer Lett. 344 2014 166 173
35. M.V. Iorio, R. Visone, G. Di Leva, V. Donati, F. Petrocca, P. Casalini, C. Taccioli, S. Volinia, C.G. Liu, H. Alder, and et al. MicroRNA signatures in human ovarian cancer Cancer Res. 67 2007 8699 8707
36. Y. Kinose, K. Sawada, K. Nakamura, and T. Kimura The role of microRNAs in ovarian cancer BioMed Res. Int. 2014 2014 249393
37. S. Zhang, I. Mercado-Uribe, S. Hanash, and J. Liu iTRAQ-based proteomic analysis of polyploid giant cancer cells and budding progeny cells reveals several distinct pathways for ovarian cancer development PLoS ONE 8 2013 e80120
38. S. Zhang, I. Mercado-Uribe, Z. Xing, B. Sun, J. Kuang, and J. Liu Generation of cancer stem-like cells through the formation of polyploid giant cancer cells Oncogene 33 2014 116 128
39. T. Davoli, and T. de Lange The causes and consequences of polyploidy in normal development and cancer Annu. Rev. Cell Dev. Biol. 27 2011 585 610
40. B. Cohen, M.E. McGuffin, C. Pfeifle, D. Segal, and S.M. Cohen apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins Genes Dev. 6 1992 715 729
41. E. Buff, A. Carmena, S. Gisselbrecht, F. Jiménez, and A.M. Michelson Signalling by the Drosophila epidermal growth factor receptor is required for the specification and diversification of embryonic muscle progenitors Development 125 1998 2075 2086
42. J.S. Karres, V. Hilgers, I. Carrera, J. Treisman, and S.M. Cohen The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila Cell 131 2007 136 145
43. J. Su, B. Chow, G.L. Boulianne, and A. Wilde The BAR domain of amphiphysin is required for cleavage furrow tip-tubule formation during cellularization in Drosophila embryos Mol. Biol. Cell 24 2013 1444 1453
44. H. Herranz, L. Pérez, F.A. Martín, and M. Milán A Wingless and Notch double-repression mechanism regulates G1-S transition in the Drosophila wing EMBO J. 27 2008 1633 1645