Spinal Cord Stimulation for Heart Failure in the DEFEAT-HF Study: Lost Battle or Lasting Opportunities?

JACC: Heart Failure

Volumn 4, Issue 2, 2016, Pages 137-139

  Upadhyay, Gaurav A ^a   Singh, Jagmeet P ^b  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Clinical trial results; Heart failure; Spinal cord stimulation

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE;

DEVICE FRACTURE; DEVICE HEMATOMA; EDITORIAL; GATE CONTROL THEORY; HEART FAILURE; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE CONTRACTILITY; HUMAN; IMPLANTED SPINAL CORD STIMULATOR; LEAD DISLODGEMENT; MEDICAL DEVICE COMPLICATION; MORTALITY; NEUROMODULATION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SPINAL CORD DORSAL HORN; SPINAL CORD STIMULATION; TREATMENT OUTCOME;

HEART FAILURE; HUMANS; SPINAL CORD STIMULATION;

EID: 84959175642     PISSN: 22131779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchf.2015.11.007     Document Type: Editorial

References (23)

1. Elkhorne J.L. Edison-the fabulous drone. 73 Magazine 1967, XLVI:52-61.
2. Melzack R., Wall P.D. Pain mechanisms: a new theory. Science 1965, 150:971-979.
3. Wall P.D., Sweet W.H. Temporary abolition of pain in man. Science 1967, 155:108-109.
4. Shealy C.N., Mortimer J.T., Reswick J.B. Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report. Anesth Analg 1967, 46:489-491.
5. Murphy D.F., Giles K.E. Dorsal column stimulation for pain relief from intractable angina pectoris. Pain 1987, 28:365-368.
6. Taylor R.S., De Vries J., Buchser E., Dejongste M.J. Spinal cord stimulation in the treatment of refractory angina: systematic review and meta-analysis of randomised controlled trials. BMC Cardiovasc Disord 2009, 9:13.
7. Foreman R.D., Linderoth B., Ardell J.L., et al. Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris. Cardiovasc Res 2000, 47:367-375.
8. Latif O.A., Nedeljkovic S.S., Stevenson L.W. Spinal cord stimulation for chronic intractable angina pectoris: a unified theory on its mechanism. Clin Cardiol 2001, 24:533-541.
9. Mannheimer C., Eliasson T., Andersson B., et al. Effects of spinal cord stimulation in angina pectoris induced by pacing and possible mechanisms of action. BMJ 1993, 307:477-480.
10. Wu M., Linderoth B., Foreman R.D. Putative mechanisms behind effects of spinal cord stimulation on vascular diseases: a review of experimental studies. Auton Neurosci 2008, 138:9-23.
11. Cui J.G., Meyerson B.A., Sollevi A., Linderoth B. Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation. Neurosci Lett 1998, 247:183-186.
12. Eliasson T., Mannheimer C., Waagstein F., et al. Myocardial turnover of endogenous opioids and calcitonin-gene-related peptide in the human heart and the effects of spinal cord stimulation on pacing-induced angina pectoris. Cardiology 1998, 89:170-177.
13. Norrsell H., Eliasson T., Mannheimer C., et al. Effects of pacing-induced myocardial stress and spinal cord stimulation on whole body and cardiac norepinephrine spillover. Eur Heart J 1997, 18:1890-1896.
14. Olgin J.E., Takahashi T., Wilson E., Vereckei A., Steinberg H., Zipes D.P. Effects of thoracic spinal cord stimulation on cardiac autonomic regulation of the sinus and atrioventricular nodes. J Cardiovasc Electrophysiol 2002, 13:475-481.
15. Issa Z.F., Zhou X., Ujhelyi M.R., et al. Thoracic spinal cord stimulation reduces the risk of ischemic ventricular arrhythmias in a postinfarction heart failure canine model. Circulation 2005, 111:3217-3220.
16. Lopshire J.C., Zhou X., Dusa C., et al. Spinal cord stimulation improves ventricular function and reduces ventricular arrhythmias in a canine postinfarction heart failure model. Circulation 2009, 120:286-294.
17. Odenstedt J., Linderoth B., Bergfeldt L., et al. Spinal cord stimulation effects on myocardial ischemia, infarct size, ventricular arrhythmia, and noninvasive electrophysiology in a porcine ischemia-reperfusion model. Heart Rhythm 2011, 8:892-898.
18. Liu Y., Yue W.S., Liao S.Y., et al. Thoracic spinal cord stimulation improves cardiac contractile function and myocardial oxygen consumption in a porcine model of ischemic heart failure. J Cardiovasc Electrophysiol 2012, 23:534-540.
19. Liao S.Y., Liu Y., Zuo M., et al. Remodelling of cardiac sympathetic re-innervation with thoracic spinal cord stimulation improves left ventricular function in a porcine model of heart failure. Europace 2015 Mar 12, [E-pub ahead of print].
20. Kujacic V., Eliasson T., Mannheimer C., Jablonskiene D., Augustinsson L.E., Emanuelsson H. Assessment of the influence of spinal cord stimulation on left ventricular function in patients with severe angina pectoris: an echocardiographic study. Eur Heart J 1993, 14:1238-1244.
21. Tse H.F., Turner S., Sanders P., et al. Thoracic Spinal Cord Stimulation for Heart Failure as a Restorative Treatment (SCS HEART study): first-in-man experience. Heart Rhythm 2015, 12:588-595.
22. Zipes D.P., Neuzil P., Theres H., et al. Determining the feasibility of spinal cord neuromodulation for the treatment of chronic systolic heart failure: the DEFEAT-HF Study. J Am Coll Cardiol HF 2016, 4:129-136.
23. Lopshire J.C., Zipes D.P. Spinal cord stimulation for heart failure: preclinical studies to determine optimal stimulation parameters for clinical efficacy. J Cardiovasc Transl Res 2014, 7:321-329.