Modulation of intrinsic cardiac neurons by spinal cord stimulation: Implications for its therapeutic use in angina pectoris

Cardiovascular Research

Volumn 47, Issue 2, 2000, Pages 367-375

  Foreman, Robert D ^a   Linderoth, Bengt ^b   Ardell, Jeffrey L ^c   Barron, Kirk W ^a   Chandler, M J ^a   Hull Jr , Stephen S ^a   Terhorst, Gert J ^d   Dejongste, Michael J L ^d   Armour, John A ^e  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c E Tennessee Stt Univ Coll Med   (United States)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^e DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Autonomic nervous system; Ischemia; Reperfusion

Indexed keywords

ANGINA PECTORIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART NERVE; MALE; NERVE CONDUCTION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD STIMULATION;

ACTION POTENTIALS; ANGINA PECTORIS; ANIMALS; AUTONOMIC NERVOUS SYSTEM; DOGS; ELECTRIC STIMULATION THERAPY; HEART; MALE; MYOCARDIAL ISCHEMIA; NEURONS; RANDOM ALLOCATION; SIGNAL PROCESSING, COMPUTER-ASSISTED; SPINAL CORD;

EID: 0033870691     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00095-X     Document Type: Article

References (31)

1. Jessurun G.A.J., Meeder J.G., DeJongste M.J.L. Defining the problem of intractable angina. Pain Rev. 4:1997;89-99.
2. Schoebel F.C., Frazier O.H., Jessurun G.A.J., DeJongste M.J.L., Kadipasaoglu K.A., Jax T.W., Heintzen M.P., Cooley D.A., Strauer B.E., Leschke M. Refractory angina pectoris in end-stage coronary artery disease: evolving therapeutic concepts. Am. Heart J. 134:1997;587-602.
3. Anderson C., Hole P., Oxhoj H. Does pain relief with spinal cord stimulation for angina conceal myocardial infarction? Br. Heart J. 71:1994;419-421.
4. Eliasson T., Augustinsson L.E., Mannheimer C. Spinal cord stimulation in severe angina pectoris-presentation of current studies, indications and clinical experience. Pain. 65:1996;169-179.
5. Hautvast R.W., DeJongste M.J., Staal M.J., van Gilst W.H., Lie K.I. Spinal electrical stimulation in chronic intractable angina pectoris: a randomized, controlled efficacy study. Am. Heart J. 136:1998;1114-1120.
6. Sanderson J.E., Ibrahim B., Waterhouse D., Palmer R.B. Spinal cord stimulation for intractable angina-long-term clinical outcome and safety. Eur. Heart J. 15:1994;810-814.
7. Sanderson J.E., Brooksby P., Waterhouse D., Palmer R.B., Neubauer K. Epidural spinal electrical stimulation for severe angina: a study of its effects on symptoms, exercise tolerance and degree of ischemia. Eur. Heart J. 13:1992;628-633.
8. Mannheimer C., Eliasson T., Andersson B., Bergh C.H., Augustinsson L.E., Emanuelsson H., Waagstein F. Effects of spinal cord stimulation in angina pectoris induced by pacing and possible mechanisms of action. Br. Med. J. 307:1993;477-480.
9. Mannheimer C., Eliasson T., Augustinsson L.E., Blomstrand C., Emanuelsson H., Larsson S., Norrsell H., Hjalmarsson A. Electrical stimulation versus coronary artery bypass surgery in severe angina pectoris. The ESBY study. Circulation. 97:1998;1157-1163.
10. Chandler M.J., Brennan T.J., Garrison D.W., Kim K.S., Schwartz P.J., Foreman R.D. A mechanism of cardiac pain supression by spinal cord stimulation: implications for patients with angina pectoris. Eur. Heart J. 14:1993;96-105.
11. Yakhnitsa V., Linderoth B., Meyerson B.A. Spinal cord stimulation attenuates dorsal horn neuronal hyperexcitability in a rat model of mononeuropathy. Pain. 79:1999;223-233.
12. Augustinsson L.E., Linderoth B., Mannheimer C., Eliasson T. Spinal cord stimulation in cardiovascular disease. Gildenberg P. Neurosurgery clinics of North America. 1995;157-165.
13. Augustinsson L.E., Linderoth B., Eliasson T., Mannheimer C. Spinal cord stimulation in peripheral vascular disease and angina pectoris. Gildenberg P., Tasker R. Textbook of stereotactic and functional neurosurgery. 1997;1973-1978 McGraw-Hill, NY.
14. Linderoth B., Gunasekera L., Meyerson B.A. Effects of sympathectomy on skin and muscle microcirculation during dorsal column stimulation: animal studies. Neurosurgery. 29:1991;874-879.
15. Linderoth B., Herregodts P., Meyerson B.A. Sympathetic mediation of peripheral vasodilation induced by spinal cord stimulation: animal studies of the role of cholinergic and adrenergic receptor subtypes. Neurosurgery. 35:1994;711-719.
16. Croom JE, Foreman RD, Chandler MJ, Barron KW. Cutaneous vasodilation during dorsal column stimulation is mediated by dorsal roots and C.G.R.P. Am J Physiol 272 (Heart Circ Physiol) 1997;272:H950-H957.
17. Ardell J.L. Structure and function of mammalian intrinsic cardiac neurons. Armour J.A., Ardell J.L. Neurocardiology. 1994;95-114 Oxford University Press, New York.
18. Armour J.A., Hopkins D.A. Activity of canine in situ left atrial ganglion neurons. Am. J. Physiol. 259:1990;H1207-H1215.
19. Gagliardi M., Randall W.C., Bieger D., Wurster R.D., Hopkins D.A., Armour J.A. Activity of in vivo canine cardiac plexus neurons. Am. J. Physiol. 255:1988;H789-800.
20. Huang M.H., Ardell J.L., Hanna B.D., Wolf S.G., Armour J.A. Effects of transient coronary artery occlusion on canine intrinsic cardiac neuronal activity. Integr. Physiol. Behav. Sci. 28:1993;5-21.
21. Huang M.H., Wolf S.G., Armour J.A. Ventricular arrhythmias induced by chemically modified intrinsic cardiac neurones. Cardiovasc. Res. 28:1994;636-642.
22. Linderoth B., Fedorcsak I., Meyerson B.A. Peripheral vasodilatation after spinal cord stimulation: animal studies of putative effector mechanisms. Neurosurgery. 28:1991;187-195.
23. Eliasson T., Mannheimer C., Waagstein F., Andersson B., Bergh C.H., Augustinsson L.E., Hedner T., Larson G. Myocardial turnover of endogenous opioids and calcitonin-gene-related peptide in the human heart and the effects of spinal cord stimulation on pacing-induced angina pectoris. Cardiology. 89:1998;170-177.
24. Armour J.A., Huang M.H., Smith F.M. Peptidergic modulation of in situ canine intrinsic cardiac neurons. Peptides. 14:1993;191-202.
25. Armour J.A. Activity of in situ middle cervical ganglion neurons in dogs, using extracellular recording techniques. Can. J. Physiol. Pharmacol. 63:1985;704-716.
26. Armour J.A. Neuronal activity recorded extracellularly in chronically decentralized in situ canine middle cervical ganglia. Can. J. Physiol. Pharmacol. 64:1986;1038-1046.
27. Butler C., Watson-Wright W.M., Wilkinson M., Johnstone D.E., Armour J.A. Cardiac effects produced by long-term stimulation of thoracic autonomic ganglia or nerves: implications for interneuronal interactions within the thoracic autonomic nervous system. Can. J. Physiol. Pharmacol. 66:1988;175-184.
28. Murphy D.A., O'Blenes S., Nassar B.A., Armour J.A. Effects of acutely raising intracranial pressure on cardiac sympathetic efferent neuron function. Cardiovasc. Res. 30:1995;716-724.
29. Armour J.A. Myocardial ischaemia and the cardiac nervous system. Cardiovasc. Res. 41:1999;41-54.
30. deJongste M.J., Nagelkerke D., Hooyschuur C.M., Journe H.L., Meyler P.W., Staal M.J., de Jonge P., Lie K.I. Stimulation characteristics, complications, and efficacy of spinal cord stimulation systems in patients with refractory angina: a prospective feasibility study. Pacing Clin. Electrophysiol. 17:1994;1751-1760.
31. Kingma J.G., Armour J.A., Rouleau J.R. Chemical modulation of in situ intrinsic cardiac neurones influences myocardial blood flow in the anesthetised dog. Cardiovasc. Res. 28:1994;1403-1406.