Spinal cord stimulation for heart failure: Preclinical studies to determine optimal stimulation parameters for clinical efficacy

Journal of Cardiovascular Translational Research

Volumn 7, Issue 3, 2014, Pages 321-329

  Lopshire, John C ^a   Zipes, Douglas P ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Animal models; Autonomic nervous system; Heart failure; Spinal cord stimulation; Ventricular arrhythmias

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; HEART ARRHYTHMIA; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE FUNCTION; HEART PACING; HEART RATE; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; MALE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD STIMULATION; TREATMENT RESPONSE; VASODILATATION; ANIMAL; AUTONOMIC NERVOUS SYSTEM; DISEASE MODEL; HUMAN; PATHOPHYSIOLOGY; PROCEDURES;

ANGINA; ANIMALIA; SUS;

ANIMALS; ARRHYTHMIAS, CARDIAC; AUTONOMIC NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; HEART FAILURE; HUMANS; SPINAL CORD STIMULATION;

EID: 84899420939     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-014-9547-7     Document Type: Article

References (18)

1. Foreman, R., Linderoth, B., Ardelt, J., et al. (2000). Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris. Cardiovascular Research, 47(2), 367-375. (Pubitemid 30625299)
2. Southerland, E. M., Milhorn, D. M., Foreman, R. D., et al. (2007). Preemptive, but not reactive, spinal cord stimulation mitigates transient ischemia-induced myocardial infarction via cardiac adrenergic neurons. American Journal of Physiology. Heart and Circulatory Physiology, 292, H311-H317. (Pubitemid 46105192)
3. Olgin, J. E., Takahashi, T., Wilson, E., et al. (2002). Effects of thoracic spinal cord stimulation on cardiac autonomic regulation of the sinus and atrioventricular nodes. Journal of Cardiovascular Electrophysiology, 13(5), 475-481. (Pubitemid 34494268)
4. Issa, Z. F., Zhou, X., Ujhelyi, M. R., et al. (2005). Thoracic spinal cord stimulation reduces the risk of ischemic ventricular arrhythmias in a post-infarction heart failure canine model. Circulation, 111(24), 3217-3220. (Pubitemid 40874992)
5. Odenstedt, J., Linderoth, B., Bergfeldt, L., et al. (2011). Spinal cord stimulation effects on myocardial ischemia, infarct size, ventricular arrhythmia, and noninvasive electrophysiology in a porcine ischemia-reperfusion model. Heart Rhythm, 8(6), 892-898.
6. Ferraro, P., Castogno, D., Massa, R., et al. (2008). Spinal cord stimulation affects T-wave alternans in patients with ischaemic cardiomyopathy: a pilot study. Europace, 10, 506-508. (Pubitemid 351767682)
7. Bernstein, S. A., Wong, B., Vasquez, C., et al. (2012). Spinal cord stimulation protects against atrial fibrillation induced by tachypacing. Heart Rhythm, 9(9), 1426-1433.
8. Lopshire, J. C., Zhou, X., Dusa, C., et al. (2009). Spinal cord stimulation improves ventricular function and reduces ventricular arrhythmias in a canine postinfarction heart failure model. Circulation, 120, 286-294.
9. Liu, Y., Yue, W. S., Liao, S. Y., et al. (2012). Thoracic spinal cord stimulation improves cardiac contractile function and myocardial oxygen consumption in a porcine model of ischemic heart failure. Journal of Cardiovascular Electrophysiology, 23(5), 534-540.
10. Tse, H.-F., Lie, Y., Zuo, M., et al. (2012). Intermittent versus continuous spinal cord stimulation for treatment of ischemic heart failure. European Heart Journal, 33, 963-964.
11. Feigenbaum, H. (2004). Echocardiography (6th ed., pp. 201-263). Baltimore: Williams and Wilkins.
12. Lopshire, J. C., & Zipes, D. P. (2012). Device therapy to modulate the autonomic nervous system to treat heart failure. Current Cardiology Reports, 14(5), 593-600.
13. Grimaldi, R., de Luca, A., Kornet, L., et al. (2012). Can spinal cord stimulation reduce ventricular arrhythmias? Heart Rhythm, 9(11), 1884-1887. doi:10.1016/j.hrthm.2012.08.007.
14. Ardell, J. L., Cardinal, R., Vermeulen, M., et al. (2009). Dorsal spinal cord stimulation obtunds the capacity of intrathoracic extracardiac neurons to transduce myocardial ischemia. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 297(2), R470-R477.
15. Determining the feasibility of spinal cord neuromodulation for the treatment of chronic heart failure (DEFEAT-HF). Available at: http://clinicaltrials.gov/ct2/show/NCT01112579. Accessed 14 Feb 2014.
16. Cornelussen, R. N., Splett, V., Klepfer, R. N., et al. (2011). Electrical modalities beyond pacing for the treatment of heart failure. Heart Failure Reviews, 16, 315-325.
17. Spinal Cord Stimulation for Heart Failure (SCS-HEART). Available at: http://clinicaltrials.gov/ct2/show/NCT01362725. Accessed 14 Feb 2014.
18. Neurostimulation of spinal nerves that affect the heart. Available at: http://clinicaltrials.gov/ct2/show/NCT01124136. Accessed 14 Feb 2014.