Myocardial turnover of endogenous opioids and calcitonin-gene-related peptide in the human heart and the effects of spinal cord stimulation on pacing-induced angina pectoris

Cardiology

Volumn 89, Issue 3, 1998, Pages 170-177

  Eliasson, Tore ^a   Mannheimer, Clas ^a   Waagstein, Finn ^a   Andersson, Bert ^a   Bergh, Claes Håkan ^a   Augustinsson, Lars Erik ^a   Hedner, Thomas ^a   Larson, Göran ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Calcitonin gene related peptide; Myocardial turnover; Opioid peptides; Spinal cord stimulation

Indexed keywords

BETA ENDORPHIN; CALCITONIN GENE RELATED PEPTIDE; ENDORPHIN; LEUCINE ENKEPHALIN;

ADULT; ANGINA PECTORIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART ATRIUM PACING; HEART CATHETERIZATION; HEART MUSCLE; HEART RIGHT ATRIUM; HUMAN; MALE; PRIORITY JOURNAL; SPINAL CORD STIMULATION;

AGED; ANGINA PECTORIS; BETA-ENDORPHIN; CALCITONIN GENE-RELATED PEPTIDE; CARDIAC PACING, ARTIFICIAL; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; ENKEPHALIN, LEUCINE; FEMALE; HEART CATHETERIZATION; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCARDIUM; RADIOIMMUNOASSAY; SPINAL CORD;

EID: 0031881785     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000006783     Document Type: Article

References (49)

1. Lang R, Hermann K, Dietz R: Evidence for the presence of enkephalins in the heart. Life Sci 1982;32:399-406.
2. Caffrey J, Gaugl J, Jones C: Local endogenous opiate activity in dog myocardium. Am J Physiol1985;248:H382-H388.
3. Forman L, Estilow S, Hock C: Localisation of beta-endorphin in the rat heart and modulation by testosterone 1 (42855). Soc Exp Biol Med 1989;190:240-245.
4. Archelos J, Xiang J, Reinecke M, Lang R: Regulation of the release and function of neuropeptides in the heart. J Cardiovasc Pharmacol 1987;10(suppl 12):S45-S50.
5. Szabo B, Hedler L, Ensinger H, Starke K: Opioid peptides decrease noradrenaline release and blood pressure in the rabbit at peripheral receptors. Arch Pharmacol 1986;332:50-56.
6. Slepushkin V, Palenko V, Zoloyev G: The role of enkephalins in the pathogenesis of acute myocardial infarction. Exp Pathol 1988;35: 129-131.
7. Falcone C, Guasti L, Ochan M, Codega S, Tortorici M, Angoli L, Bergamaschi R, Montemartini C: Beta-endorphins during coronary angioplasty in patients with silent or symptomatic myocardial ischemia. Eur Heart J 1993;22: 1614-1620.
8. Oldroyd K, Harvey K, Gray C, Beastall G, Cobbe S: β-Endorphin release in patients after spontaneous and provoked acute myocardial ischemia. Br Heart J 1992;67:230-235.
9. Miller PF, Light KC, Bragdon EE, Ballenger MN, Herbst MC, Maixner W, Hinderliter AL, Atkinson SS, Koch GG, Sheps DS: Beta-endorphin response to exercise and mental stress in patients with ischemic heart disease. J Psychosom Res 1993;37:455-465.
10. Napolitano L, Chernow B: Endorphins in circulatory shock. Crit Care Med 1988;16:566-567.
11. Wallbridge D, MacIntyre H, Gray C, Denvir M, Oldroyd K, Rae A, Cobbe M: Increase in plasma β-endorphins precedes vasodepressor syncope. Br Heart J 1994;71:446-448.
12. Holaday J: Cardiovascular effects of endogenous opiate systems. Ann Rev Pharmacol Toxicol 1983;23:541-594.
13. Mulderry P, Ghatei M, Ropdrigo J: Calcitonin gene related peptide in cardiovascular tissues of the rat. Neuroscience 1985;14:947-954.
14. Franco-Cereceda A, Bengtsson L, Lundberg J: Inotropic effects of calcitonin gene related peptide, vasoactive intestinal polypeptide and somatostatin on the human right atrium in vivo. Eur J Pharmacol 1987;134:69-76.
15. Brain S, Williams T, Tippins J, Morris H, Maclntyre J: Calcitonin gene related peptide is a potent vasodilator. Nature 1985;313:54-56.
16. Lechleitner P, Genser N, Mair J, Dienstl A, Haring C, Wiedermann C, Puschendorf B, Saria A, Dienstl F: Calcitonine gene-related peptide in patients with and without early reperfusion after acute myocardial infarction. Am Heart J 1992;124:1433-1439.
17. Sylven C: Angina pectoris. Clinical characteristics, neurophysiological and molecular mechanisms. Pain 1989;36:145-167.
18. Mannheimer C, Emanuelsson H, Waagstein F, Wilhelmsson C: Influence of naloxone on the effects of high frequency transcutaneous electrical nerve stimulation in angina pectoris induced by atrial pacing. Br Heart J 1989;62:36-42.
19. Mannheimer C, Augustinsson L-E, Carlsson C-A, Manhem K, Wilhelmsson C: Epidural spinal electrical stimulation in severe angina pectoris. Br Heart J 1988;59:56-61.
20. Sanderson JE, Brooksby P, Waterhouse D, Palmer RBG, Neubauer K: Epidural spinal electrical stimulation for severe angina: A study of its effects on symptoms, exercise tolerance and degree of ischaemia. Eur Heart J 1992;13:628-633.
21. Eliasson T, Albertsson P, Hårdhammar P, Emanuelsson H, Augustinsson L-E, Mannheimer C: Spinal cord stimulation in angina pectoris with normal coronary arteriograms. Coron Artery Dis 1993;4:819-827.
22. De Jongste M, Haaksma J, Hautvast R, Hillege H, Meyler P, Staal M, Sanderson J, Lie K: Effects of spinal cord stimulation on myocardial ischemia during daily life in patients with severe coronary artery disease. Br Heart J 1993;71:413-418.
23. Mannheimer C, Eliasson T, Andersson B, Berg H, Augustinsson L-E, Emanuelsson H, Waagstein F: Effects of spinal cord stimulation in angina pectoris induced by pacing and possible mechanisms of action. BMJ 1993;307:477-480.
24. Eliasson T, Mannheimer C: Spinal cord stimulation in severe angina pectoris - presentation of current studies, indications and practical experience. Pain 1996;65:169-179.
25. Thadani U, Lewis J, Mathew T, West R, Parker J: Reproducibility of clinical and hemodynamic parameters during pacing stress testing in patients with angina pectoris. Circulation 1979;60:1036-1041.
26. Ihle H, Simonsen S, Vatne K: Reproducibility of ischemic lactate metabolism during atrial pacing in man. Cardiology 1983;70:177-183.
27. Remme WJ: Myocardial lactate metabolism - the gold standard when evaluating interventions in ischemia. Eur Heart J 1992; 13(abstract suppl):362.
28. Borg G: A category scale with ratio properties for intermodal and interindividual comparisons; in Petzold H-GGaP (ed): Psychophysical judgement and the progress of perception. Berlin. VEB Deutscher Verlag der Wissenschaften, 1982, pp 25-34.
29. Venn R: Combined high-performance liquid chromatographic-radioimmunoassay method for the analysis of endorphins, enkephalins and other neurotransmittor peptides. J Chromatogr 1987;423:93-104.
30. Grunditz T, Ekman R, Håkansson R, Rerup C, Sundler F, Uddman R: Calcitonin-gene related peptide in thyroid nerve fibres and C-cells. Effects on thyroid hormone secretion and response in hypercalcemia. Endocrinology 1986; 119;2313-2323.
31. Bradley JW: Distribution-free statistical tests. London, Prentice-Hall, 1968, pp 68-86.
32. Lehmann E: Testing statistical hypotheses. New York, Wiley, 1986.
33. Ode A, Wedel H: Arguments for Fisher's permutation test. Ann Stat 1975;3:518-520.
34. Farsang C, Kapocsi J, Juhasz I, Kunos G: Possible involvement of an endogenous opiate in the anti-hypertensive effect of clonidine in essential hypertension. Circulation 1982;66: 1268-1282.
35. Farsang C, Varga K, Vajda L: Beta-endorphin contributes to the antihypertensive effect of clonidine in a subset of patients with essential hypertension. Neuropeptides 1984;4:293-302.
36. Grossman A, Smith R, van Loon G, Brown G, Rees L, Besser G: Circulating catecholamines, melatonin and enkephalin in man following administration of a metenkephalin analogue. Neuroendocrinol Lett 1982;4:223-232.
37. De Bold C, Nicholson W, Orth D: Immunoreactive propiomelanocortin (POMC) peptides and POMC-like messenger rubonucleic acid are present in many rat nonpituitary tissues. Endocrinology 1988;122:2648-2657.
38. Rosenquist G, Maruthainar K, Smyth D: Beta-endorphin is present in active and inactive forms in rat gastric antrum. Biochem Biophys Res Commun 1986;134:14-20.
39. Smyth D, Zakarian S: Alpha-n-acetyl derivatives of beta-endorphin in rat pituitary: Chromatographic evidence for processed forms of beta-endorphin in pancreas and brain. Life Sci 1982;31:1887-1890.
40. Clarke J: Perivascular peptides in the coronary circulation: Relation to pathophysiology; in Edvinsson L, Uddman R (eds): Vascular innervation and receptor mechanisms - new perspectives. San Diego, Harcourt Brace Jovanovich, 1993.
41. Ludman P, Maseri A, Clark P, Davies G: Effects of calcitonin-gene related peptide on normal and atheromatous vessels and on resistance vessels in the coronary circulation in humans. Circulation 1991;84:1993-2000.
42. Taguchi T, Karasaki H, Imamura T, Takasaki K: Endogenous calcitonin-gene related peptide mediates nonadrenergic noncholinergic depressor response to spinal cord stimulation in the pithed rat. Circ Res 1992;71:357-364.
43. Cribier A, Korsatz L, Koning R, Rath P, Gamra H, Stix G: Improved myocardial ischemic response and enhanced collateral circulation with long repetitive coronary occlusion during angioplasty. J Am Coll Cardiol 1992;20:578-586.
44. Deutsch E, Berger M, Kussmaul W, Hirschfeld J, Hermann H, Laskey M: Adaptation to ischemia during percutaneous transluminal coronary angioplasty. Clinical, hemodynamic and metabolic features. Circulation 1990;82:578-586.
45. Cohen M, Downey J: Ischemic preconditioning: Can the question be bottled? Lancet 1993; 342:6.
46. Marber MS, Walker DM, Eveson DJ, Walker JM, Yellon DM: A single five minute period of rapid atrial pacing fails to limit infarct size in the in situ rabbit heart. Cardiovasc Res 1993; 27:597-601.
47. Jackson G, Atkinson L, Oram S: Improvement of myocardial metabolism in coronary arterial disease by beta-blockade. Br Heart J 1977;39: 829-833.
48. Diodati JG, Cannon ROr, Hussain N, Quyyumi AA: Inhibitory effect of nitroglycerin and sodium nitroprusside on platelet activation across the coronary circulation in stable angina pectoris. Am J Cardiol 1995;75:443-448.
49. Grover GJ, Schumacher WA, Ogletree ML: Thromboxane receptor antagonist BMS-180291, but not aspirin, reduces the severity of pacing-induced ischemia in dogs. J Cardiovasc Pharmacol 1994;24:493-499.