Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2-/- (C57BL/6) Mice

Radiation Research

Volumn 185, Issue 2, 2016, Pages 134-150

  Shinde, Ashwin ^a   Berhane, Hebist ^a   Rhieu, Byung Han ^a   Kalash, Ronny ^a   Xu, Karen ^a   Goff, Julie ^a   Epperly, Michael W ^a   Franicola, Darcy ^a   Zhang, Xichen ^a   Dixon, Tracy ^a   Shields, Donna ^a   Wang, Hong ^a   Wipf, Peter ^c   Parmar, Kalindi ^b   Guinan, Eva ^b   Kagan, Valerian ^d   Tyurin, Vladimir ^d   Ferris, Robert L ^e   Zhang, Xiaolan ^f   Li, Song ^f   Greenberger, Joel S ^a   more..

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Departments of Chemistry and Bioengineering

^d Departments of Environmental Occupational Health

^e Departments of Otolaryngology

^f UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JP 40 039; NITROXIDE; PROTEIN P21; PROTEIN P53; RAD51 PROTEIN; RADIOPROTECTIVE AGENT; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; FANCD2 PROTEIN, MOUSE; FANCONI ANEMIA GROUP D2 PROTEIN; JP4-039; NITROGEN OXIDE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DISTRIBUTION; EMULSION; EPITHELIUM CELL; GENE EXPRESSION; GENOTYPE; MITOCHONDRION; MOUSE; MOUTH CAVITY; MOUTH TUMOR; MOUTH ULCER; NONHUMAN; ORAL MUCOSITIS; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RADIATION PROTECTION; RADIATION RESPONSE; RADIOSENSITIZATION; TUMOR MICROENVIRONMENT; WILD TYPE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; METABOLISM; MOUTH MUCOSA; MOUTH NEOPLASMS; ORAL DRUG ADMINISTRATION; ORGANS AT RISK; PATHOLOGY; RADIATION TOLERANCE; TREATMENT OUTCOME; TUMOR CELL LINE;

ADMINISTRATION, ORAL; ANIMALS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, RADIATION; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MOUTH MUCOSA; MOUTH NEOPLASMS; NITROGEN OXIDES; ORGANS AT RISK; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; TREATMENT OUTCOME;

EID: 84959157729     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR14035.1     Document Type: Article

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