Association of klotho polymorphisms with healthy aging: A systematic review and meta-analysis

Rejuvenation Research

Volumn 17, Issue 2, 2014, Pages 212-216

  Di Bona, Danilo ^a   Accardi, Giulia ^a   Virruso, Claudia ^a   Candore, Giuseppina ^a   Caruso, Calogero ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

KLOTHO PROTEIN; BETA GLUCURONIDASE;

AGING; ARTICLE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; LONGEVITY; META ANALYSIS; OBSERVATIONAL STUDY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW; ADULT; AGED; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; HEALTH; INFANT; MIDDLE AGED; NEWBORN; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AGING; CASE-CONTROL STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GLUCURONIDASE; HEALTH; HUMANS; INFANT; INFANT, NEWBORN; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84898949273     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2013.1523     Document Type: Article

References (20)

1. Caruso C, Passarino G, Puca A, Scapagnini G. "Positive biology": The centenarian lesson. Immun Ageing 2012;9:5.
2. Montesanto A, Dato S, Bellizzi D, Rose G, Passarino G. Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevity. Immun Ageing 2012; 9:6.
3. Ferrario A, Villa F, Malovini A, Araniti F, Puca AA. The application of genetics approaches to the study of exceptional longevity in humans: Potential and limitations. Immun Ageing 2012;9:7.
4. Incalcaterra E, Accardi G, Balistreri CR, Caimi G, Candore G, Caruso M, Caruso C. Pro-inflammatory genetic markers of atherosclerosis. Curr Atheroscler Rep 2013;15:329-337.
5. Salvioli S, Olivieri F, Marchegiani F, Cardelli M, Santoro A, Bellavista E, Mishto M, Invidia L, Capri M, Valensin S, Sevini F, Cevenini E, Celani L, Lescai F, Gonos E, Caruso C, Paolisso G, De Benedictis G, Monti D, Franceschi C. Genes, ageing and longevity in humans: Problems, advantages and perspectives. Free Radic Res 2006;40:1303-1323. (Pubitemid 44698280)
6. Franceschi C, Motta L, Motta M, Malaguarnera M, Capri M, Vasto S, Candore G, Caruso C; IMUSCE. The extreme longevity: The state of the art in Italy. Exp Gerontol 2008; 43:45-52.
7. Capri M, Salvioli S, Monti D, Caruso C, Candore G, Vasto S, Olivieri F, Marchegiani F, Sansoni P, Baggio G, Mari D, PassarinoG, De Benedictis G, Franceschi C. Human longevity within an evolutionary perspective: The peculiar paradigm of a post-reproductive genetics. Exp Gerontol 2008;43:53-60.
8. Beekman M, Blanché H, Perola M, Hervonen A, Bezrukov V, Sikora E, Flachsbart F, Christiansen L, De Craen AJ, Kirkwood TB, Rea IM, Poulain M, Robine JM, Valensin S, Stazi MA, Passarino G, Deiana L, Gonos ES, Paternoster L, Srensen TI, Tan Q, Helmer Q, van den Akker EB, Deelen J, Martella F, Cordell HJ, Ayers KL, Vaupel JW, Törnwall O, Johnson TE, Schreiber S, Lathrop M, Skytthe A, Westendorp RG, Christensen K, Gampe J, Nebel A, Houwing-Duistermaat JJ, Slagboom PE, Franceschi C; GEHA Consortium. Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. Aging Cell 2013;12:184-193.
9. Di Bona D, Accardi G, Virruso C, Candore G, Caruso C. Association between genetic variations in the insulin/insulinlike growth factor (IGF-1) signaling pathway and longevity: A systematic review and meta-analysis. Curr Vasc Pharmacol 2013; Dec 18. [Epub ahead of print]
10. Kuro-o M. Klotho and aging. Biochim Biophys Acta 2009; 1790:1049-1058.
11. Wang Y, Sun Z. Current understanding of klotho. Ageing Res Rev 2009;8:43-51.
12. Arking DE, Krebsova A, Macek M Sr, Macek M Jr, Arking A, Mian IS, Fried L, Hamosh A, Dey S, McIntosh I, Dietz HC. Association of human aging with a functional variant of klotho. Proc Natl Acad Sci USA 2002;99:856-861. (Pubitemid 34106600)
13. Novelli V, Viviani Anselmi C, Roncarati R, Guffanti G, Malovini A, Piluso G, Puca AA. Lack of replication of genetic associations with human longevity. Biogerontology 2008;9:85-92.
14. Invidia L, Salvioli S, Altilia S, Pierini M, Panourgia MP, Monti D, De Rango F, Passarino G, Franceschi C. The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect. Biogerontology 2010;11:67-73.
15. Majumdar V, Nagaraja D, Christopher R. Association of the functional KL-VS variant of Klotho gene with earlyonset ischemic stroke. Biochem Biophys Res Commun 2010;403:412-416.
16. DerSimonian R, Laird N. Meta-analysis in clinical trials. Controlled Clin Trials 1986;7:177-188. (Pubitemid 17189972)
17. Arking DE, Becker DM, Yanek LR, Fallin D, Judge DP, Moy TF, Becker LC, Dietz HC. KLOTHO allele status and the risk of early-onset occult coronary artery disease. Am J Hum Genet 2003;72:1154-1161 (Pubitemid 36530003)
18. Arking DE, Atzmon G, Arking A, Barzilai N, Dietz HC. Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity. Circ Res 2005;96:412-418 (Pubitemid 40354534)
19. Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M. Suppression of aging in mice by the hormone Klotho. Science. 2005;309:1829-1833 (Pubitemid 41325087)
20. Ziv E, Hu D. Genetic variation in insulin/IGF-1 signaling pathways and longevity. Ageing Res Rev 2011;10:201-204.