메뉴 건너뛰기




Volumn 48, Issue 4, 2016, Pages 1721-1729

The milk-derived hexapeptide PGPIPN inhibits the invasion and migration of human ovarian cancer cells by regulating the expression of MTA1 and NM23H1 genes

Author keywords

gene expression; invasion; migration; ovarian cancer cell; peptide

Indexed keywords

ANTINEOPLASTIC AGENT; HEXAPEPTIDE; MESSENGER RNA; PROLYLGLYCYLPROLYLISOLEUCYLPROLYLASPARGINE; UNCLASSIFIED DRUG; HISTONE DEACETYLASE; MTA1 PROTEIN, HUMAN; NME1 PROTEIN, HUMAN; NUCLEOSIDE DIPHOSPHATE KINASE NM23; OLIGOPEPTIDE; REPRESSOR PROTEIN;

EID: 84958999470     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2016.3390     Document Type: Article
Times cited : (13)

References (31)
  • 3
    • 77956285631 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer
    • European Organization for Research and Treatment of Cancer-Gynaecological Cancer Group; NCIC Clinical Trials Group
    • Vergote I, Tropé CG, Amant F, Kristensen GB, Ehlen T, Johnson N, Verheijen RH, van der Burg ME, Lacave AJ, Panici PB, et al; European Organization for Research, and Treatment of Cancer-Gynaecological Cancer Group; NCIC Clinical Trials Group: Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer. N Engl J Med. 363: 943-953, 2010.
    • (2010) N Engl J Med , vol.363 , pp. 943-953
    • Vergote, I.1    Tropé, C.G.2    Amant, F.3    Kristensen, G.B.4    Ehlen, T.5    Johnson, N.6    Verheijen, R.H.7    Van Der Burg, M.E.8    Lacave, A.J.9    Panici, P.B.10
  • 5
    • 24944504306 scopus 로고    scopus 로고
    • Biological effects of milk proteins, and their peptides with emphasis on those related to the gastrointestinal ecosystem
    • Baldi A, Ioannis P, Chiara P, Eleonora F, Roubini C, and Vittorio D. Biological effects of milk proteins, and their peptides with emphasis on those related to the gastrointestinal ecosystem. J Dairy Res 72 (S1): 66-72, 2005.
    • (2005) J Dairy Res , vol.72 , Issue.S1 , pp. 66-72
    • Baldi, A.1    Ioannis, P.2    Chiara, P.3    Eleonora, F.4    Roubini, C.5    Vittorio, D.6
  • 7
    • 9344246896 scopus 로고    scopus 로고
    • Targeting gastrinreleasing peptide receptors for cancer treatment
    • Zhou J, Chen J, Mokotoff M, and Ball ED. Targeting gastrinreleasing peptide receptors for cancer treatment. Anticancer Drugs. 15: 921-927, 2004.
    • (2004) Anticancer Drugs , vol.15 , pp. 921-927
    • Zhou, J.1    Chen, J.2    Mokotoff, M.3    Ball, E.D.4
  • 8
    • 33746842648 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment
    • Mader JS, and Hoskin DW. Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment. Expert Opin Investig Drugs. 15: 933-946, 2006.
    • (2006) Expert Opin Investig Drugs , vol.15 , pp. 933-946
    • Mader, J.S.1    Hoskin, D.W.2
  • 9
    • 84875986442 scopus 로고    scopus 로고
    • PGPIPN, a therapeutic hexapeptide, suppressed human ovarian cancer growth by targeting BCL2
    • Wang W, Gu F, Wei C, Tang Y, Zheng X, Ren M, and Qin Y. PGPIPN, a therapeutic hexapeptide, suppressed human ovarian cancer growth by targeting BCL2. PLoS One. 8: e60701, 2013.
    • (2013) PLoS One , vol.8 , pp. e60701
    • Wang, W.1    Gu, F.2    Wei, C.3    Tang, Y.4    Zheng, X.5    Ren, M.6    Qin, Y.7
  • 10
    • 0027357826 scopus 로고
    • Biologically active peptides from milk proteins with emphasis on two examples concerning antithrombotic, and immunomodulating activities
    • Fiat AM, Migliore-Samour D, Jollès P, Drouet L, Bal dit Sollier C, and Caen J. Biologically active peptides from milk proteins with emphasis on two examples concerning antithrombotic, and immunomodulating activities. J Dairy Sci. 76: 301-310, 1993.
    • (1993) J Dairy Sci , vol.76 , pp. 301-310
    • Fiat, A.M.1    Migliore-Samour, D.2    Jollès, P.3    Drouet, L.4    Bal dit Sollier, C.5    Caen, J.6
  • 11
    • 0031254723 scopus 로고    scopus 로고
    • Antiproliferative effects of yogurt fractions obtained by membrane dialysis on cultured mammalian intestinal cells
    • Ganjam LS, Thornton WH Jr, Marshall RT, and MacDonald RS. Antiproliferative effects of yogurt fractions obtained by membrane dialysis on cultured mammalian intestinal cells. J Dairy Sci. 80: 2325-2329, 1997.
    • (1997) J Dairy Sci , vol.80 , pp. 2325-2329
    • Ganjam, L.S.1    Thornton, W.H.2    Marshall, R.T.3    MacDonald, R.S.4
  • 12
    • 0029924099 scopus 로고    scopus 로고
    • Stimulation of human peripheral blood lymphocytes by bioactive peptides derived from bovine milk proteins
    • Kayser H, and Meisel H. Stimulation of human peripheral blood lymphocytes by bioactive peptides derived from bovine milk proteins. FEBS Lett. 383: 18-20, 1996.
    • (1996) FEBS Lett , vol.383 , pp. 18-20
    • Kayser, H.1    Meisel, H.2
  • 13
    • 0030749136 scopus 로고    scopus 로고
    • Biochemical properties of regulatory peptides derived from milk proteins
    • Meisel H. Biochemical properties of regulatory peptides derived from milk proteins. Biopolymers. 43: 119-128, 1997.
    • (1997) Biopolymers , vol.43 , pp. 119-128
    • Meisel, H.1
  • 14
    • 0038397187 scopus 로고    scopus 로고
    • Biofunctional peptides from milk proteins: Mineral binding, and cytomodulatory effects
    • Meisel H, and FitzGerald RJ. Biofunctional peptides from milk proteins: Mineral binding, and cytomodulatory effects. Curr Pharm Des. 9: 1289-1295, 2003.
    • (2003) Curr Pharm des , vol.9 , pp. 1289-1295
    • Meisel, H.1    FitzGerald, R.J.2
  • 15
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-Time quantitative PCR, and the 2(-Delta Delta C(T)) method
    • Livak KJ, and Schmittgen TD. Analysis of relative gene expression data using real-Time quantitative PCR, and the 2(-Delta Delta C(T)) method. Methods. 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 18
    • 84921909998 scopus 로고    scopus 로고
    • RGD-conjugated solid lipid nanoparticles inhibit adhesion, and invasion of avβ3 integrin-overexpressing breast cancer cells
    • Shan D, Li J, Cai P, Prasad P, Liu F, Rauth AM, and Wu XY. RGD-conjugated solid lipid nanoparticles inhibit adhesion, and invasion of avβ3 integrin-overexpressing breast cancer cells. Drug Deliv Transl Res. 5: 15-26, 2015.
    • (2015) Drug Deliv Transl Res , vol.5 , pp. 15-26
    • Shan, D.1    Li, J.2    Cai, P.3    Prasad, P.4    Liu, F.5    Rauth, A.M.6    Wu, X.Y.7
  • 19
    • 84901951020 scopus 로고    scopus 로고
    • Potential clinical applications of multi-functional milk proteins, and peptides in cancer management
    • Chen HY, Mollstedt O, Tsai MH, and Kreider RB. Potential clinical applications of multi-functional milk proteins, and peptides in cancer management. Curr Med Chem. 21: 2424-2437, 2014.
    • (2014) Curr Med Chem , vol.21 , pp. 2424-2437
    • Chen, H.Y.1    Mollstedt, O.2    Tsai, M.H.3    Kreider, R.B.4
  • 20
    • 84940380637 scopus 로고    scopus 로고
    • Bioactive properties of milk proteins in humans: A review
    • Nongonierma AB, and FitzGerald RJ. Bioactive properties of milk proteins in humans: A review. Peptides. 73: 20-34, 2015.
    • (2015) Peptides , vol.73 , pp. 20-34
    • Nongonierma, A.B.1    FitzGerald, R.J.2
  • 23
    • 0027213138 scopus 로고
    • Candidate metastasisassociated genes of the rat 13762NF mammary adenocarcinoma
    • Pencil SD, Toh Y, and Nicolson GL. Candidate metastasisassociated genes of the rat 13762NF mammary adenocarcinoma. Breast Cancer Res Treat. 25: 165-174, 1993.
    • (1993) Breast Cancer Res Treat , vol.25 , pp. 165-174
    • Pencil, S.D.1    Toh, Y.2    Nicolson, G.L.3
  • 24
    • 0027978984 scopus 로고
    • A novel candidate metastasis-Associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines cDNA cloning, expression and protein analyses
    • Toh Y, Pencil SD, and Nicolson GL. A novel candidate metastasis-Associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression and protein analyses. J Biol Chem. 269: 22958-22963, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 22958-22963
    • Toh, Y.1    Pencil, S.D.2    Nicolson, G.L.3
  • 25
    • 0029029343 scopus 로고
    • Analysis of the complete sequence of the novel metastasis-Associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma, and breast cancer cell lines
    • Toh Y, Pencil SD, and Nicolson GL. Analysis of the complete sequence of the novel metastasis-Associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma, and breast cancer cell lines. Gene. 159: 97-104, 1995.
    • (1995) Gene , vol.159 , pp. 97-104
    • Toh, Y.1    Pencil, S.D.2    Nicolson, G.L.3
  • 26
    • 0030863876 scopus 로고    scopus 로고
    • Overexpression of the MTA1 gene in gastrointestinal carcinomas: Correlation with invasion, and metastasis
    • Toh Y, Oki E, Oda S, Tokunaga E, Ohno S, Maehara Y, Nicolson GL, and Sugimachi K. Overexpression of the MTA1 gene in gastrointestinal carcinomas: Correlation with invasion, and metastasis. Int J Cancer. 74: 459-463, 1997.
    • (1997) Int J Cancer , vol.74 , pp. 459-463
    • Toh, Y.1    Oki, E.2    Oda, S.3    Tokunaga, E.4    Ohno, S.5    Maehara, Y.6    Nicolson, G.L.7    Sugimachi, K.8
  • 27
    • 0032911744 scopus 로고    scopus 로고
    • Molecular cloning, mapping and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-Associated gene, MTA1
    • Futamura M, Nishimori H, Shiratsuchi T, Saji S, Nakamura Y, and Tokino T. Molecular cloning, mapping and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-Associated gene, MTA1. J Hum Genet. 44: 52-56, 1999.
    • (1999) J Hum Genet , vol.44 , pp. 52-56
    • Futamura, M.1    Nishimori, H.2    Shiratsuchi, T.3    Saji, S.4    Nakamura, Y.5    Tokino, T.6
  • 28
    • 0035352840 scopus 로고    scopus 로고
    • Expression of nm23 in breast cancer: Correlation with distant metastasis, and prognosis
    • In Chinese
    • Liu H, Mao H, and Fu X. Expression of nm23 in breast cancer: Correlation with distant metastasis, and prognosis. Zhonghua Zhong Liu Za Zhi. 23: 224-227, 2001 (In Chinese
    • (2001) Zhonghua Zhong Liu Za Zhi , vol.23 , pp. 224-227
    • Liu, H.1    Mao, H.2    Fu, X.3
  • 29
    • 0035240434 scopus 로고    scopus 로고
    • mRNA expression, and mutation of MTA1, and nm23H1 genes in ovarian carcinoma in relation to lymph node metastasis
    • In Chinese
    • Huang G, Song Y, and He G. mRNA expression, and mutation of MTA1, and nm23H1 genes in ovarian carcinoma in relation to lymph node metastasis. Zhonghua Zhong Liu Za Zhi. 23: 31-34, 2001 (In Chinese).
    • (2001) Zhonghua Zhong Liu Za Zhi , vol.23 , pp. 31-34
    • Huang, G.1    Song, Y.2    He, G.3
  • 31
    • 79952814571 scopus 로고    scopus 로고
    • The influence of μ-opioid receptor agonist, and antagonist peptides on peripheral blood mononuclear cells (PBMCs
    • Fiedorowicz E, Jarmolowska B, Iwan M, Kostyra E, Obuchowicz R, and Obuchowicz M. The influence of μ-opioid receptor agonist, and antagonist peptides on peripheral blood mononuclear cells (PBMCs). Peptides. 32: 707-712, 2011.
    • (2011) Peptides , vol.32 , pp. 707-712
    • Fiedorowicz, E.1    Jarmolowska, B.2    Iwan, M.3    Kostyra, E.4    Obuchowicz, R.5    Obuchowicz, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.