The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells

International Journal of Oncology

Volumn 48, Issue 3, 2016, Pages 1039-1044

  Notaro, Antonietta ^a   Sabella, Selenia ^a   Pellerito, Ornella ^b   Vento, Renza ^a   Calvaruso, Giuseppe ^a   Giuliano, Michela ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Apoptosis; Cannabinoids; Caspase 8 activation; Osteosarcoma; SPARC

Indexed keywords

CANNABINOID RECEPTOR AGONIST; CASPASE 8; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; OSTEONECTIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; WIN 55 212 2; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; BENZOXAZINE DERIVATIVE; CASP8 PROTEIN, HUMAN; MORPHOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE; SPARC PROTEIN, HUMAN; TNFSF10 PROTEIN, HUMAN;

ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; GENE SILENCING; HUMAN; HUMAN CELL; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION; WESTERN BLOTTING; APOPTOSIS; BONE TUMOR; CELL SURVIVAL; CHEMISTRY; ENDOPLASMIC RETICULUM STRESS; METABOLISM; PATHOLOGY; PROTEIN DOMAIN; TUMOR CELL LINE;

APOPTOSIS; BENZOXAZINES; BONE NEOPLASMS; CASPASE 8; CELL DEATH; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; HUMANS; MORPHOLINES; NAPHTHALENES; OSTEONECTIN; OSTEOSARCOMA; PROTEIN DOMAINS; RNA INTERFERENCE; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84958999341     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.3307     Document Type: Article

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