The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma

International Journal of Oncology

Volumn 42, Issue 1, 2013, Pages 188-196

  Sailaja, G S ^a   Bhoopathi, Praveen ^a   Gorantla, Bharathi ^a   Chetty, Chandramu ^a   Gogineni, Venkateswara Rao ^a   Velpula, Kiran Kumar ^a   Gondi, Christopher S ^a   Rao, Jasti S ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Apoptosis; Autophagy; Endoplasmic reticulum stress; Neuroblastoma; Secreted protein acidic and rich in cysteine

Indexed keywords

CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; OSTEONECTIN; PLASMID VECTOR; PROTEIN KINASE R; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IRRADIATION; NEUROBLASTOMA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; UNFOLDED PROTEIN RESPONSE;

APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CASPASE 3; COMBINED MODALITY THERAPY; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; HUMANS; IMMUNOENZYME TECHNIQUES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NEUROBLASTOMA; OSTEONECTIN; PHOSPHORYLATION; RADIATION, IONIZING; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; TUMOR CELLS, CULTURED; UNFOLDED PROTEIN RESPONSE;

EID: 84873658356     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1678     Document Type: Article

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