메뉴 건너뛰기




Volumn 11, Issue 2, 2016, Pages 203-212

Multiplex diagnosis of oncogenic fusion and met exon skipping by molecular counting using formalin-fixed paraffin embedded lung adenocarcinoma tissues

Author keywords

Genetic diagnosis; MET exon skipping; Molecular counting; Oncogene fusion; Personalized medicine

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; B RAF KINASE; NEU DIFFERENTIATION FACTOR; PROTEIN RET; SCATTER FACTOR RECEPTOR; FORMALDEHYDE; MESSENGER RNA; MET PROTEIN, HUMAN; PARAFFIN;

EID: 84958951896     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1016/j.jtho.2015.10.005     Document Type: Article
Times cited : (22)

References (35)
  • 1
    • 84888646015 scopus 로고    scopus 로고
    • Tyrosine kinase gene rearrangements in epithelial malignancies
    • Shaw AT, Hsu PP, Awad MM, Engelman JA. Tyrosine kinase gene rearrangements in epithelial malignancies. Nat Rev Cancer. 2013;13:772-787.
    • (2013) Nat Rev Cancer , vol.13 , pp. 772-787
    • Shaw, A.T.1    Hsu, P.P.2    Awad, M.M.3    Engelman, J.A.4
  • 2
    • 84875947292 scopus 로고    scopus 로고
    • New targetable oncogenes in non-small-cell lung cancer
    • Oxnard GR, Binder A, Janne PA. New targetable oncogenes in non-small-cell lung cancer. J Clin Oncol. 2013;31:1097-1104.
    • (2013) J Clin Oncol , vol.31 , pp. 1097-1104
    • Oxnard, G.R.1    Binder, A.2    Janne, P.A.3
  • 3
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. New Engl J Med. 2010;363:1693-1703.
    • (2011) New Engl J Med , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 4
    • 84896957081 scopus 로고    scopus 로고
    • Ceritinib in ALKrearranged non-small-cell lung cancer
    • Shaw AT, Kim DW, Mehra R, et al. Ceritinib in ALKrearranged non-small-cell lung cancer. New Engl J Med. 2014;370:1189-1197.
    • (2014) New Engl J Med , vol.370 , pp. 1189-1197
    • Shaw, A.T.1    Kim, D.W.2    Mehra, R.3
  • 5
    • 84878347085 scopus 로고    scopus 로고
    • CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): A single-Arm, open-label, phase 1-2 study
    • Seto T, Kiura K, Nishio M, et al. CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): A single-Arm, open-label, phase 1-2 study. Lancet Oncol. 2013;14: 590-598.
    • (2013) Lancet Oncol , vol.14 , pp. 590-598
    • Seto, T.1    Kiura, K.2    Nishio, M.3
  • 6
    • 84857985225 scopus 로고    scopus 로고
    • RET ROS1 and ALK fusions in lung cancer
    • Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med. 2012;18:378-381.
    • (2012) Nat Med , vol.18 , pp. 378-381
    • Takeuchi, K.1    Soda, M.2    Togashi, Y.3
  • 7
    • 84858815363 scopus 로고    scopus 로고
    • ROS1 rearrangements in lung cancer: A new genomic subset of lung adenocarcinoma
    • Janne PA, Meyerson M. ROS1 rearrangements in lung cancer: A new genomic subset of lung adenocarcinoma. J Clin Oncol. 2012;30:878-879.
    • (2012) J Clin Oncol , vol.30 , pp. 878-879
    • Janne, P.A.1    Meyerson, M.2
  • 8
    • 84857929267 scopus 로고    scopus 로고
    • KIF5B-RET fusions in lung adenocarcinoma
    • Kohno T, Ichikawa H, Totoki Y, et al. KIF5B-RET fusions in lung adenocarcinoma. Nat Med. 2012;18:375-377.
    • (2012) Nat Med , vol.18 , pp. 375-377
    • Kohno, T.1    Ichikawa, H.2    Totoki, Y.3
  • 9
    • 84862776857 scopus 로고    scopus 로고
    • Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
    • Lipson D, Capelletti M, Yelensky R, et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med. 2012;18:382-384.
    • (2012) Nat Med , vol.18 , pp. 382-384
    • Lipson, D.1    Capelletti, M.2    Yelensky, R.3
  • 10
    • 84875224942 scopus 로고    scopus 로고
    • ROS1-rearranged lung cancer: A clinicopathologic and molecular study of 15 surgical cases
    • Yoshida A, Kohno T, Tsuta K, et al. ROS1-rearranged lung cancer: A clinicopathologic and molecular study of 15 surgical cases. Am J Surg Pathol. 2013;37:554-562.
    • (2013) Am J Surg Pathol , vol.37 , pp. 554-562
    • Yoshida, A.1    Kohno, T.2    Tsuta, K.3
  • 12
    • 84922722792 scopus 로고    scopus 로고
    • Crizotinib in ROS1-rearranged non-small-cell lung cancer
    • Shaw AT, Ou SH, Bang YJ, et al. Crizotinib in ROS1-rearranged non-small-cell lung cancer. New Engl J Med. 2015;372:683-684.
    • (2015) New Engl J Med , vol.372 , pp. 683-684
    • Shaw, A.T.1    Ou, S.H.2    Bang, Y.J.3
  • 13
    • 84969533090 scopus 로고    scopus 로고
    • Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer
    • [e-pub ahead of print] accessed January 4 2016
    • Falchook GS, Ordonez NG, Bastida CC, et al. Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer [e-pub ahead of print]. J Clin Oncol. http://dx.doi.org/10.1200/JCO.2013.50.5016 accessed January 4, 2016.
    • J Clin Oncol
    • Falchook, G.S.1    Ordonez, N.G.2    Bastida, C.C.3
  • 14
    • 84902682450 scopus 로고    scopus 로고
    • Druggable oncogene fusions in invasive mucinous lung adenocarcinoma
    • Nakaoku T, Tsuta K, Ichikawa H, et al. Druggable oncogene fusions in invasive mucinous lung adenocarcinoma. Clin Cancer Res. 2014;20:3087-3093.
    • (2014) Clin Cancer Res , vol.20 , pp. 3087-3093
    • Nakaoku, T.1    Tsuta, K.2    Ichikawa, H.3
  • 16
    • 31544462584 scopus 로고    scopus 로고
    • Somatic mutations lead to an oncogenic deletion of met in lung cancer
    • Kong-Beltran M, Seshagiri S, Zha J, et al. Somatic mutations lead to an oncogenic deletion of met in lung cancer. Cancer Res. 2006;66:283-289.
    • (2006) Cancer Res , vol.66 , pp. 283-289
    • Kong-Beltran, M.1    Seshagiri, S.2    Zha, J.3
  • 17
    • 61549138135 scopus 로고    scopus 로고
    • Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers
    • Onozato R, Kosaka T, Kuwano H, Sekido Y, Yatabe Y, Mitsudomi T. Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers. J Thorac Oncol. 2009;4:5-11.
    • (2009) J Thorac Oncol , vol.4 , pp. 5-11
    • Onozato, R.1    Kosaka, T.2    Kuwano, H.3    Sekido, Y.4    Yatabe, Y.5    Mitsudomi, T.6
  • 18
    • 84938815085 scopus 로고    scopus 로고
    • Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping
    • Paik PK, Drilon A, Yu H, et al. Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping. Cancer Discov. 2015;5:842-849.
    • (2015) Cancer Discov , vol.5 , pp. 842-849
    • Paik, P.K.1    Drilon, A.2    Yu, H.3
  • 19
    • 84938805958 scopus 로고    scopus 로고
    • Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
    • Frampton GM, Ali SM, Rosenzweig M, et al. Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. Cancer Discov. 2015;5:850-859.
    • (2015) Cancer Discov , vol.5 , pp. 850-859
    • Frampton, G.M.1    Ali, S.M.2    Rosenzweig, M.3
  • 20
    • 84899472081 scopus 로고    scopus 로고
    • Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma
    • Mizukami T, Shiraishi K, Shimada Y, et al. Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma. J Thorac Oncol. 2014;9:622-630.
    • (2014) J Thorac Oncol , vol.9 , pp. 622-630
    • Mizukami, T.1    Shiraishi, K.2    Shimada, Y.3
  • 21
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Network CGAR
    • Network CGAR. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014;511:543-550.
    • (2014) Nature , vol.511 , pp. 543-550
  • 22
    • 84884211534 scopus 로고    scopus 로고
    • Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer
    • Lira ME, Kim TM, Huang D, et al. Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer. J Mol Diagn. 2013;15: 51-61.
    • (2013) J Mol Diagn , vol.15 , pp. 51-61
    • Lira, M.E.1    Kim, T.M.2    Huang, D.3
  • 23
    • 84894066256 scopus 로고    scopus 로고
    • A single-Tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer
    • Lira ME, Choi YL, Lim SM, et al. A single-Tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer. J Mol Diagn. 2014;16:229-243.
    • (2014) J Mol Diagn , vol.16 , pp. 229-243
    • Lira, M.E.1    Choi, Y.L.2    Lim, S.M.3
  • 24
    • 84901826745 scopus 로고    scopus 로고
    • Clinicopathological features of non-small cell lung carcinomas with BRAF mutations
    • Kinno T, Tsuta K, Shiraishi K, et al. Clinicopathological features of non-small cell lung carcinomas with BRAF mutations. Ann Oncol. 2014;25:138-142.
    • (2014) Ann Oncol , vol.25 , pp. 138-142
    • Kinno, T.1    Tsuta, K.2    Shiraishi, K.3
  • 25
    • 84939439876 scopus 로고    scopus 로고
    • Development of lung adenocarcinomas with exclusive dependence on oncogene fusions
    • Saito M, Shimada Y, Shiraishi K, et al. Development of lung adenocarcinomas with exclusive dependence on oncogene fusions. Cancer Res. 2015;75:2264-2271.
    • (2015) Cancer Res , vol.75 , pp. 2264-2271
    • Saito, M.1    Shimada, Y.2    Shiraishi, K.3
  • 27
    • 79960268207 scopus 로고    scopus 로고
    • GPHMM: An integrated hidden Markov model for identification of copy number alteration and loss of heterozygosity in complex tumor samples using whole genome SNP arrays
    • Li A, Liu Z, Lezon-Geyda K, et al. GPHMM: An integrated hidden Markov model for identification of copy number alteration and loss of heterozygosity in complex tumor samples using whole genome SNP arrays. Nucl Acids Res. 2011;39:4928-4941.
    • (2011) Nucl Acids Res , vol.39 , pp. 4928-4941
    • Li, A.1    Liu, Z.2    Lezon-Geyda, K.3
  • 28
    • 84944447298 scopus 로고    scopus 로고
    • Beyond ALK-RET ROS1 and other oncogene fusions in lung cancer
    • Kohno T, Nakaoku T, Tsuta K, et al. Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer. Transl Lung Cancer Res. 2015;4:156-164.
    • (2015) Transl Lung Cancer Res , vol.4 , pp. 156-164
    • Kohno, T.1    Nakaoku, T.2    Tsuta, K.3
  • 29
    • 84868309107 scopus 로고    scopus 로고
    • The transcriptional landscape and mutational profile of lung adenocarcinoma
    • Seo JS, Ju YS, Lee WC, et al. The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res. 2012;22:2109-2119.
    • (2012) Genome Res , vol.22 , pp. 2109-2119
    • Seo, J.S.1    Ju, Y.S.2    Lee, W.C.3
  • 30
    • 84858335323 scopus 로고    scopus 로고
    • C-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas
    • Tsuta K, Kozu Y, Mimae T, et al. c-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas. J Thorac Oncol. 2012;7:331-339.
    • (2012) J Thorac Oncol , vol.7 , pp. 331-339
    • Tsuta, K.1    Kozu, Y.2    Mimae, T.3
  • 31
    • 84887445619 scopus 로고    scopus 로고
    • Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
    • Vaishnavi A, Capelletti M, Le AT, et al. Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer. Nat Med. 2013;19:1469-1472.
    • (2013) Nat Med , vol.19 , pp. 1469-1472
    • Vaishnavi, A.1    Capelletti, M.2    Le, A.T.3
  • 32
    • 84938270856 scopus 로고    scopus 로고
    • BIRC6-ALK, a novel fusion gene in ALK break-Apart FISH-negative lung adenocarcinoma, responds to crizotinib
    • Shan L, Jiang P, Xu F, et al. BIRC6-ALK, a novel fusion gene in ALK break-Apart FISH-negative lung adenocarcinoma, responds to crizotinib. J Thorac Oncol. 2015;10:e37-e39.
    • (2015) J Thorac Oncol , vol.10 , pp. e37-e39
    • Shan, L.1    Jiang, P.2    Xu, F.3
  • 33
    • 84929600898 scopus 로고    scopus 로고
    • Common oncogene mutations and novel SND1-BRAF transcript fusion in lung adenocarcinoma from never smokers
    • Jang JS, Lee A, Li J, et al. Common oncogene mutations and novel SND1-BRAF transcript fusion in lung adenocarcinoma from never smokers. Sci Rep. 2015;5: 9755.
    • (2015) Sci Rep , vol.5 , pp. 9755
    • Jang, J.S.1    Lee, A.2    Li, J.3
  • 34
    • 84929501704 scopus 로고    scopus 로고
    • Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling
    • Ou SH, Chalmers ZR, Azada MC, et al. Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling. Lung Cancer. 2015;88:352-354.
    • (2015) Lung Cancer , vol.88 , pp. 352-354
    • Ou, S.H.1    Chalmers, Z.R.2    Azada, M.C.3
  • 35
    • 84884762173 scopus 로고    scopus 로고
    • Comparison of PAM50 risk of recurrence score with oncotype DX and IHC4 for predicting risk of distant recurrence after endocrine therapy
    • Dowsett M, Sestak I, Lopez-Knowles E, et al. Comparison of PAM50 risk of recurrence score with oncotype DX and IHC4 for predicting risk of distant recurrence after endocrine therapy. J Clin Oncol. 2013;31:2783-2790.
    • (2013) J Clin Oncol , vol.31 , pp. 2783-2790
    • Dowsett, M.1    Sestak, I.2    Lopez-Knowles, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.