Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma

Journal of Thoracic Oncology

Volumn 9, Issue 5, 2014, Pages 622-630

  Mizukami, Tatsuji ^a,b   Shiraishi, Kouya ^a   Shimada, Yoko ^a   Ogiwara, Hideaki ^a   Tsuta, Koji ^c   Ichikawa, Hitoshi ^a   Sakamoto, Hiromi ^a   Kato, Mamoru ^a   Shibata, Tatsuhiro ^a   Nakano, Takashi ^b   Kohno, Takashi ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER CENTER HOSPITAL   (Japan)

Author keywords

DNA strand break; Gene fusion; Lung adenocarcinoma; Molecular target therapy; Personalized medicine; RET

Indexed keywords

CABOZANTINIB; GENOMIC DNA; PROTEIN TYROSINE KINASE INHIBITOR; VANDETANIB; CCDC6 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; DNA; KIF5B PROTEIN, HUMAN; KINESIN; ONCOPROTEIN; PROTEIN RET; RET PROTEIN, HUMAN;

ARTICLE; CHROMOSOME INVERSION; CLINICAL ARTICLE; CLONING; DNA REPAIR; DNA STRAND BREAKAGE; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; GENE MUTATION; GENOME; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; INTRON; LUNG ADENOCARCINOMA; LUNG CANCER; MOLECULARLY TARGETED THERAPY; NUCLEOTIDE SEQUENCE; ONCOGENE RET; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; THYROID PAPILLARY CARCINOMA; ADENOCARCINOMA; CARCINOGENESIS; CHROMOSOME BREAKAGE; DNA END JOINING REPAIR; GENETIC VARIABILITY; GENETICS; LUNG TUMOR; MOLECULAR GENETICS; PATHOLOGY;

ADENOCARCINOMA; CARCINOGENESIS; CHROMOSOME BREAKPOINTS; CHROMOSOME INVERSION; CYTOSKELETAL PROTEINS; DNA END-JOINING REPAIR; DNA, NEOPLASM; EXONS; GENETIC VARIATION; HUMANS; INTRONS; KINESIN; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; ONCOGENE PROTEINS, FUSION; PROTO-ONCOGENE PROTEINS C-RET;

EID: 84899472081     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000135     Document Type: Article

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