Molecular basis of polyspecificity of the Small Multidrug Resistance Efflux Pump AbeS from Acinetobacter baumannii

Journal of Molecular Biology

Volumn 428, Issue 3, 2016, Pages 644-657

  Lytvynenko, Iryna ^a   Brill, Shlomo ^b   Oswald, Christine ^a   Pos, Klaas M ^a  

^a GOETHE UNIVERSITY   (Germany)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Antibiotic resistance; EmrE; Membrane transport; Reconstitution; Substrate promiscuity

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ACRIFLAVINE; AMINO ACID; ANTIPORTER; BENZALKONIUM; ETHIDIUM; LIPOSOME; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN EMRE; TETRAPHENYLPHOSPHONIUM; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; EMRE PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN;

ABES GENE; ACINETOBACTER BAUMANNII; ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; GENE; IC50; MULTIDRUG RESISTANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ACINETOBACTER INFECTIONS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ESCHERICHIA COLI; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; POINT MUTATION; SEQUENCE ALIGNMENT; TRANSPORT AT THE CELLULAR LEVEL;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIPORTERS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 84958911587     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.12.006     Document Type: Article

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