Restoration of T cell function in chronic hepatitis B patients upon treatment with interferon based combination therapy

Journal of Hepatology

Volumn 64, Issue 3, 2016, Pages 539-546

  De Niet, Annikki ^a   Stelma, Femke ^a   Jansen, Louis ^a   Sinnige, Marjan J ^a   Remmerswaal, Ester B M ^a   Takkenberg, R Bart ^a   Kootstra, Neeltje A ^a   Reesink, Hendrik W ^a   Van Lier, Rene A W ^a,b   Van Leeuwen, Ester M M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b SANQUIN RESEARCH   (Netherlands)

Author keywords

Adaptive immunity; Combination therapy; HBsAg loss; HBV specific T cells; Hepatitis B

Indexed keywords

ADEFOVIR DIPIVOXIL; GRANZYME B; HEPATITIS B SURFACE ANTIGEN; INTERLEUKIN 2; PEGINTERFERON ALPHA2A; PERFORIN; VIRUS DNA; ANTIVIRUS AGENT; CYTOKINE; INTERFERON;

ADULT; AGED; ARTICLE; CELL PROLIFERATION; CHRONIC HEPATITIS B; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE RESPONSE; DRUG RESPONSE; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MALE; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TREATMENT OUTCOME; TREATMENT RESPONSE; VIRAL CLEARANCE; VIRUS LOAD; BIOSYNTHESIS; BLOOD; COMBINATION DRUG THERAPY; CYTOTOXICITY; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; IMMUNOLOGY; MIDDLE AGED; VIROLOGY;

ADULT; AGED; ANTIVIRAL AGENTS; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DRUG THERAPY, COMBINATION; FEMALE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; INTERFERONS; MALE; MIDDLE AGED; T-LYMPHOCYTES; VIRAL LOAD;

EID: 84958868149     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.10.013     Document Type: Article

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