Th17 cytokines disrupt the airway mucosal barrier in chronic rhinosinusitis

Mediators of Inflammation

Volumn 2016, Issue , 2016, Pages

  Ramezanpour, Mahnaz ^a   Moraitis, Sophia ^a   Smith, Jason L P ^b   Wormald, P J ^a   Vreugde, Sarah ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; INTERFERON; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 26; PROTEIN ZO1; ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; IFNG PROTEIN, HUMAN; IL26 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22;

ARTICLE; CELL MEMBRANE PERMEABILITY; CHRONIC RHINOSINUSITIS; ELECTRIC RESISTANCE; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOLOCALIZATION; NOSE POLYP; PERMEABILITY; POST HOC ANALYSIS; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT MUCOSA; TH1 CELL; TH17 CELL; TH2 CELL; BLOOD; CELL CULTURE; FEMALE; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; SINUSITIS;

CELLS, CULTURED; FEMALE; HUMANS; INTERFERON-ALPHA; INTERFERON-BETA; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKINS; MALE; MIDDLE AGED; NASAL POLYPS; SINUSITIS; TH17 CELLS;

EID: 84958824573     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2016/9798206     Document Type: Article

References (35)

1. S. Lee and A. P. Lane, "Chronic rhinosinusitis as amultifactorial inflammatory disorder, " Current Infectious Disease Reports, vol. 13, no. 2, pp. 159-168, 2011.
2. E. B. Kern, D. Sherris, A. M. Stergiou, L. M. Katz, L. C. Rosenblatt, and J. Ponikau, "Diagnosis and treatment of chronic rhinosinusitis: focus on intranasal Amphotericin B, " Therapeutics and Clinical Risk Management, vol. 3, no. 2, pp. 319-325, 2007.
3. ABS. Australian Health Survey, 2012, http://www.abs.gov.au/ausstats/abs.nsf/Lookup/4364.0.55.001main+features12011-12.
4. M. B. Soyka, A. Treis, T. Eiwegger et al., "Regulation and expression of IL-32 in chronic rhinosinusitis, " Allergy, vol. 67, no. 6, pp. 790-798, 2012.
5. M. B. Soyka, P. Wawrzyniak, T. Eiwegger et al., "Defective epithelial barrier in chronic rhinosinusitis: the regulation of tight junctions by IFN-γ and IL-4, " The Journal of Allergy and Clinical Immunology, vol. 130, no. 5, pp. 1087. e10-1096. e10, 2012.
6. T. Van Zele, S. Claeys, P. Gevaert et al., "Differentiation of chronic sinus diseases by measurement of inflammatory mediators, " Allergy, vol. 61, no. 11, pp. 1280-1289, 2006.
7. J. L. Banyer, N. H. R. Hamilton, I. A. Ramshaw, and A. J. Ramsay, "Cytokines in innate and adaptive immunity, " Reviews in Immunogenetics, vol. 2, no. 3, pp. 359-373, 2000.
8. C. T. Capaldo and A. Nusrat, "Cytokine regulation of tight junctions, " Biochimica et Biophysica Acta (BBA)-Biomembranes, vol. 1788, no. 4, pp. 864-871, 2009.
9. S. K. Wise, A. M. Laury, E. H. Katz, K. A. Den Beste, C. A. Parkos, and A. Nusrat, "Interleukin-4 and interleukin-13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression, " International Forum of Allergy and Rhinology, vol. 4, no. 5, pp. 361-370, 2014.
10. Y. Shen, X.-Y. Tang, Y.-C. Yang et al., "Impaired balance of Th17/Treg in patients with nasal polyposis, " Scandinavian Journal of Immunology, vol. 74, no. 2, pp. 176-185, 2011.
11. S. Babu and T. B. Nutman, "Proinflammatory cytokines dominate the early immune response to filarial parasites, " Journal of Immunology, vol. 171, no. 12, pp. 6723-6732, 2003.
12. T. Biedermann, M. Röcken, and J. M. Carballido, "TH1 and TH2 lymphocyte development and regulation of TH cellmediated immune responses of the skin, " Journal of Investigative Dermatology Symposium Proceedings, vol. 9, no. 1, pp. 5-14, 2004.
13. M. M. Fort, J. Cheung, D. Yen et al., "IL-25 Induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo, " Immunity, vol. 15, no. 6, pp. 985-995, 2001.
14. K. Moro, T. Yamada, M. Tanabe et al., "Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells, " Nature, vol. 463, no. 7280, pp. 540-544, 2010.
15. P. J. Dubin and J. K. Kolls, "Th17 cytokines and mucosal immunity, " Immunological Reviews, vol. 226, no. 1, pp. 160-171, 2008.
16. Z. Malik, E. Roscioli, J. Murphy et al., "Staphylococcus aureus impairs the airway epithelial barrier in vitro, " International Forum of Allergy & Rhinology, vol. 5, no. 6, pp. 551-556, 2015.
17. A. Bassiouni, J. Ou, S. Rajiv, D. Cantero, S. Vreugde, and P. Wormald, "Subepithelial inflammatory load and basement membrane thickening in refractory chronic rhinosinusitis with nasal polyposis: a histopathological study, " International Forum of Allergy & Rhinology, 2015.
18. C. J. Watson, C. J. Hoare, D. R. Garrod, G. L. Carlson, and G. Warhurst, "Interferon-γ selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores, " Journal of Cell Science, vol. 118, no. 22, pp. 5221-5230, 2005.
19. K. A. Den Beste, E. K. Hoddeson, C. A. Parkos, A. Nusrat, and S. K. Wise, "Epithelial permeability alterations in an in vitro air-liquid interfacemodel of allergic fungal rhinosinusitis, " International Forum of Allergy and Rhinology, vol. 3, no. 1, pp. 19-25, 2013.
20. J. D. Zuckerman, W. Y. Lee, J. M. DelGaudio et al., "Pathophysiology of nasal polyposis: the role of desmosomal junctions, " American Journal of Rhinology, vol. 22, no. 6, pp. 589-597, 2008.
21. M. S. Blum, E. Toninelli, J. M. Anderson et al., "Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines, " American Journal of Physiology-Heart and Circulatory Physiology, vol. 273, no. 1, pp. H286-H294, 1997.
22. A. Youakim and M. Ahdieh, "Interferon-γ decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin, " The American Journal of Physiology-Gastrointestinal and Liver Physiology, vol. 276, no. 5, pp. G1279-G1288, 1999.
23. M. Ahdieh, T. Vandenbos, and A. Youakim, "Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-gamma, " The American Journal of Physiology-Cell Physiology, vol. 281, no. 6, pp. C2029-C2038, 2001.
24. K. S. Grant-Tschudy and C. R. Wira, "Paracrine mediators of mouse uterine epithelial cell transepithelial resistance in culture, " Journal of Reproductive Immunology, vol. 67, no. 1-2, pp. 1-12, 2005.
25. S. Yoshihara, K. Kondo, K. Kanaya et al., "Tumour necrosis factor inhibitor-associated sinusitis, " Rhinology, vol. 52, no. 3, pp. 246-251, 2014.
26. B. Saatian, F. Rezaee, S. Desando et al., "Interleukin-4 and interleukin-13 cause barrier dysfunction in human airway epithelial cells, " Tissue Barriers, vol. 1, no. 2, Article ID e24333, 2013.
27. C. Cooksley, E. Roscioli, P. J. Wormald, and S. Vreugde, "TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells, " Molecular Immunology, vol. 68, no. 2, pp. 476-483, 2015.
28. C. Bachert, R. Pawankar, L. Zhang et al., "ICON: chronic rhinosinusitis, " World Allergy Organization Journal, vol. 7, no. 1, article 25, 2014.
29. J. Zhao, C. M. Lloyd, and A. Noble, "Th17 responses in chronic allergic airway inflammation abrogate regulatory Tcell-mediated tolerance and contribute to airway remodeling, " Mucosal Immunology, vol. 6, no. 2, pp. 335-346, 2013.
30. C. Blaschitz and M. Raffatellu, "Th17 cytokines and the gut mucosal barrier, " Journal of Clinical Immunology, vol. 30, no. 2, pp. 196-203, 2010.
31. G. Ciprandi, M. De Amici, G. Murdaca et al., "Serum interleukin-17 levels are related to clinical severity in allergic rhinitis, " Allergy, vol. 64, no. 9, pp. 1375-1378, 2009.
32. X.-D. Jiang, G.-Y. Li, L. Li, Z. Dong, and D.-D. Zhu, "The characterization of IL-17A expression in patients with chronic rhinosinusitiswith nasal polyps, "American Journal of Rhinology & Allergy, vol. 25, no. 5, pp. e171-e175, 2011.
33. M. Ahdieh, T. Vandenbos, and A. Youakim, "Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-γ, " American Journal of Physiology-Cell Physiology, vol. 281, no. 6, pp. 2029-2038, 2001.
34. K. Matter, S. Aijaz, A. Tsapara, and M. S. Balda, "Mammalian tight junctions in the regulation of epithelial differentiation and proliferation, " Current Opinion in Cell Biology, vol. 17, no. 5, pp. 453-458, 2005.
35. M. S. Balda, M. D. Garrett, and K. Matter, "The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density, " The Journal of Cell Biology, vol. 160, no. 3, pp. 423-432, 2003.