Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 7, 2016, Pages E854-E863

  Cheung, Kevin J ^a,b   Padmanaban, Veena ^a   Silvestri, Vanesa ^a   Schipper, Koen ^a   Cohen, Joshua D ^a   Fairchild, Amanda N ^a   Gorin, Michael A ^a   Verdone, James E ^a   Pienta, Kenneth J ^a   Bader, Joel S ^c   Ewald, Andrew J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c Johns Hopkins University   (United States)

Author keywords

Breast cancer; Collective dissemination; Collective invasion; Keratin 14; Polyclonal metastasis

Indexed keywords

CYTOKERATIN 14; EPIREGULIN; JAGGED1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TENASCIN; KRT14 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST METASTASIS; CANCER STAGING; CELL ADHESION; CELL AGGREGATION; COLONY FORMATION; CONTROLLED STUDY; DESMOSOME; EPITHELIUM TUMOR; EX VIVO STUDY; GENE OVEREXPRESSION; HEMIDESMOSOME; IN VIVO STUDY; LUNG METASTASIS; MICROMETASTASIS; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; RNA SEQUENCE; ANIMAL; BREAST TUMOR; DISEASE MODEL; GENETICS; HUMAN; METASTASIS; PATHOLOGY;

ANIMALS; BREAST NEOPLASMS; DISEASE MODELS, ANIMAL; HUMANS; KERATIN-14; MICE; NEOPLASM METASTASIS;

EID: 84958818284     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1508541113     Document Type: Article

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