Increased peripheral vascular disease risk progressively constrains perfusion adaptability in the skeletal muscle microcirculation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 310, Issue 4, 2016, Pages H488-H504

  Frisbee, Jefferson C ^a   Butcher, Joshua T ^a   Frisbee, Stephanie J ^a   Olfert, I Mark ^a   Chantler, Paul D ^a   Tabone, Lawrence E ^a   d’Audiffret, Alexandre C ^a   Shrader, Carl D ^a   Goodwill, Adam G ^a   Stapleton, Phoebe A ^a   Brooks, Steven D ^a   Brock, Robert W ^a   Lombard, Julian H ^b  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Blood flow regulation; Microvascular dysfunction; Peripheral vascular disease; Rodent models of cardiovascular disease risk; System biology of microcirculation

Indexed keywords

ACETYLCHOLINE; ARACHIDONIC ACID; DOCUSATE SODIUM; MYOGENIC FACTOR; NITRIC OXIDE; THROMBOXANE A2; FRUCTOSE; SODIUM INTAKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTICLE; BIOAVAILABILITY; BLOOD FLOW; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR RISK; CONTROLLED STUDY; CREMASTER MUSCLE; DISEASE ACTIVITY; DISEASE SEVERITY; HYPERTENSION; MALE; MICROCIRCULATION; MUSCLE PERFUSION; MUSCLE TWITCH; NONHUMAN; PERIPHERAL VASCULAR DISEASE; PREDICTIVE VALUE; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; ANIMAL; ARTERIOLE; DAHL RAT; METABOLISM; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PERFUSION; PHARMACOLOGY; PHYSIOLOGY; RENOVASCULAR HYPERTENSION; RISK ASSESSMENT; SODIUM INTAKE; SPONTANEOUSLY HYPERTENSIVE RAT; SPRAGUE DAWLEY RAT; VASCULARIZATION; ZUCKER RAT;

ANIMALS; ARTERIOLES; FRUCTOSE; HYPERTENSION, RENAL; MICROCIRCULATION; MUSCLE, SKELETAL; NITRIC OXIDE; OXYGEN CONSUMPTION; PERFUSION; PERIPHERAL VASCULAR DISEASES; RATS; RATS, INBRED DAHL; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; RATS, ZUCKER; RISK ASSESSMENT; SODIUM, DIETARY; THROMBOXANE A2;

EID: 84958568627     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00790.2015     Document Type: Article

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