Effects of three permeases on arginine utilization in Saccharomyces cerevisiae

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Zhang, Peng ^a,b   Du, Guocheng ^a,b   Zou, Huijun ^c   Chen, Jian ^a,b   Xie, Guangfa ^c   Shi, Zhongping ^a,b   Zhou, Jingwen ^a,b  

^a JIANGNAN UNIVERSITY   (China)

^b Synergetic Innovation Center of Food Safety and Nutrition   (China)

^c Zhejiang Guvuelongshan Shaoxing Wine Company   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSPORTER; ARGININE; GAP1 PROTEIN, S CEREVISIAE; HFI1 PROTEIN, S CEREVISIAE; NITROGEN; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

BACTERIAL COUNT; DEFICIENCY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; TRANSPORT AT THE CELLULAR LEVEL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID TRANSPORT SYSTEMS; ARGININE; BIOLOGICAL TRANSPORT; COLONY COUNT, MICROBIAL; GENE EXPRESSION REGULATION, FUNGAL; MUTATION; NITROGEN; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84958528229     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20910     Document Type: Article

References (34)

1. Nel, M. J., Woodiwiss, A. J. & Candy, G. P. Modeling of cellular arginine uptake by more than one transporter. J. Membr. Biol. 245, 1-13 (2012).
2. Morris, S. M., Jr. Arginine metabolism: boundaries of our knowledge. J. Nutr. 137, 1602S-1609S (2007).
3. Ljungdahl, P. O. & Daignan-Fornier, B. Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae. Genetics 190, 885-929 (2012).
4. Hoffmann, W. Molecular characterization of the CAN1 locus in Saccharomyces cerevisiae. A transmembrane protein without N-terminal hydrophobic signal sequence. J. Biol. Chem. 260, 11831-11837 (1985).
5. Opekarova, M., Caspari, T. & Tanner, W. Unidirectional arginine transport in reconstituted plasma-membrane vesicles from yeast overexpressing CAN1. Eur. J. Biochem. 211, 683-688 (1993).
6. Debailleul, F. et al. Nitrogen catabolite repressible GAP1 promoter, a new tool for efficient recombinant protein production in S. cerevisiae. Microb. Cell Fact. 12, 129 (2013).
7. Uemura, T., Kashiwagi, K. & Igarashi, K. Uptake of putrescine and spermidine by Gap1p on the plasma membrane in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 328, 1028-1033 (2005).
8. Sychrova, H. & Chevallier, M. R. APL1, a yeast gene encoding a putative permease for basic amino acids. Yeast 10, 653-657 (1994).
9. Regenberg, B., During-Olsen, L., Kielland-Brandt, M. C. & Holmberg, S. Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr. Genet. 36, 317-328 (1999).
10. Shimazu, M., Sekito, T., Akiyama, K., Ohsumi, Y. & Kakinuma, Y. A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. J. Biol. Chem. 280, 4851-4857 (2005).
11. Smart, W. C., Coffman, J. A. & Cooper, T. G. Combinatorial regulation of the Saccharomyces cerevisiae CAR1 (arginase) promoter in response to multiple environmental signals. Mol. Cell Biol. 16, 5876-5887 (1996).
12. Govind, C. K., Yoon, S., Qiu, H., Govind, S. & Hinnebusch, A. G. Simultaneous recruitment of coactivators by Gcn4p stimulates multiple steps of transcription in vivo. Mol. Cell Biol. 25, 5626-5638 (2005).
13. Scherens, B., Feller, A., Vierendeels, F., Messenguy, F. & Dubois, E. Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term. FEMS Yeast Res. 6, 777-791 (2006).
14. Rai, R., Tate, J. J., Nelson, D. R. & Cooper, T. G. gln3 mutations dissociate responses to nitrogen limitation (nitrogen catabolite repression) and rapamycin inhibition of TorC1. J. Biol. Chem. 288, 2789-2804 (2013).
15. Zaman, S., Lippman, S. I., Zhao, X. & Broach, J. R. How Saccharomyces responds to nutrients. Annu. Rev. Genet. 42, 27-81 (2008).
16. MacGurn, J. A., Hsu, P. C., Smolka, M. B. & Emr, S. D. TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell 147, 1104-1117 (2011).
17. Lin, C. H., MacGurn, J. A., Chu, T., Stefan, C. J. & Emr, S. D. Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135, 714-725 (2008).
18. Polo, S. & Di Fiore, P. P. Finding the right partner: science or ART? Cell 135, 590-592 (2008).
19. Boeckstaens, M., Llinares, E., Van Vooren, P. & Marini, A. M. The TORC1 effector kinase Npr1 fine tunes the inherent activity of the Mep2 ammonium transport protein. Nat. Commun. 5, 3101 (2014).
20. Saenz, D. A., Chianelli, M. S. & Stella, C. A. L-phenylalanine transport in Saccharomyces cerevisiae: participation of GAP1, BAP2, and AGP1. J. Amino Acids 2014, 283962 (2014).
21. Marini, A. M., Springael, J. Y., Frommer, W. B. & Andre, B. Cross-talk between ammonium transporters in yeast and interference by the soybean SAT1 protein. Mol. Microbiol. 35, 378-385 (2000).
22. Van Zeebroeck, G., Bonini, B. M., Versele, M. & Thevelein, J. M. Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nat. Chem. Biol. 5, 45-52 (2009).
23. Natarajan, K. et al. Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol. Cell Biol. 21, 4347-4368 (2001).
24. Grenson, M., Mousset, M., Wiame, J. M. & Bechet, J. Multiplicity of the amino acid permeases in Saccharomyces cerevisiae. I. Evidence for a specific arginine-transporting system. Biochim. Biophys. Acta 127, 325-338 (1966).
25. De Craene, J. O., Soetens, O. & Andre, B. The Npr1 kinase controls biosynthetic and endocytic sorting of the yeast Gap1 permease. J. Biol. Chem. 276, 43939-43948 (2001).
26. Sychrova, H. & Chevallier, M. R. Apl1, a yeast gene encoding a putative permease for basic-amino-acids. Yeast 10, 653-657 (1994).
27. Brachmann, C. B. et al. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14, 115-132 (1998).
28. Gueldener, U., Heinisch, J., Koehler, G. J., Voss, D. & Hegemann, J. H. A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast. Nucleic. Acids Res. 30, e23 (2002).
29. Wach, A. PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae. Yeast 12, 259-265 (1996).
30. Gietz, D., St Jean, A., Woods, R. A. & Schiestl, R. H. Improved method for high efficiency transformation of intact yeast cells. Nucleic. Acids Res. 20, 1425 (1992).
31. Zondler, L. et al. DJ-1 interactions with alpha-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease. Cell Death Dis. 5, e1350 (2014).
32. Zhao, X. et al. Nitrogen regulation involved in the accumulation of urea in Saccharomyces cerevisiae. Yeast 30, 437-447 (2013).
33. Zhao, X. R. et al. Metabolic engineering of the regulators in nitrogen catabolite repression to reduce the production of ethyl carbamate in a model rice wine system. Appl. Environ. Microbiol. 80, 392-398 (2014).
34. Boer, V. M. et al. Transcriptional responses of Saccharomyces cerevisiae to preferred and nonpreferred nitrogen sources in glucoselimited chemostat cultures. FEMS Yeast Res. 7, 604-620 (2007).