Wenyang Huazhuo Tongluo formula, a Chinese herbal decoction, improves skin fibrosis by promoting apoptosis and inhibiting proliferation through down-regulation of survivin and cyclin D1 in systemic sclerosis

BMC Complementary and Alternative Medicine

Volumn 16, Issue 1, 2016, Pages

  Han, Li ^a   Bian, Hua ^a   Ouyang, Jingfeng ^b   Bi, Yuefeng ^c   Yang, Lei ^a   Ye, Songshan ^a  

^a NANYANG INSTITUTE OF TECHNOLOGY   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^c ZHENGZHOU UNIVERSITY   (China)

Author keywords

Anti fibrosis; Cyclin D1; Survivin; Systemic sclerosis; Wenyang Huazhuo Tongluo formula

Indexed keywords

7,8 DIHYDRO 2 [4 (TRIFLUOROMETHYL)PHENYL] 5H THIOPYRANO[4,3 D]PYRIMIDIN 4 OL; ANTIFIBROTIC AGENT; CYCLIN D1; HERBACEOUS AGENT; MESSENGER RNA; SURVIVIN; UNCLASSIFIED DRUG; WENYANG HUAZHUO TONGLUO; BIRC5 PROTEIN, HUMAN; CCND1 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; WENYANG HUAZHO TONGLUO;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIFIBROTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SKIN BIOPSY; SKIN FIBROBLAST; SKIN FIBROSIS; SYSTEMIC SCLEROSIS; ANIMAL; CELL CULTURE; DRUG EFFECTS; FIBROSIS; METABOLISM; PATHOLOGY; SCLERODERMA, SYSTEMIC; SKIN; SKIN DISEASES; WISTAR RAT;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FEMALE; FIBROSIS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; RATS; RATS, WISTAR; SCLERODERMA, SYSTEMIC; SKIN; SKIN DISEASES;

EID: 84958279701     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1056-6     Document Type: Article

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