Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-Infection in the Absence of Viral Suppression

Immunity

Volumn 44, Issue 2, 2016, Pages 391-405

  Kløverpris, Henrik N ^a,b   Kazer, Samuel W ^c,d,e   Mjösberg, Jenny ^f   Mabuka, Jenniffer M ^a   Wellmann, Amanda ^a   Ndhlovu, Zaza ^a   Yadon, Marisa C ^a   Nhamoyebonde, Shepherd ^a   Muenchhoff, Maximilian ^a,g   Simoni, Yannick ^h   Andersson, Frank ⁱ   Kuhn, Warren ^j   Garrett, Nigel ^a,k   Burgers, Wendy A ^l   Kamya, Philomena ^a,c   Pretorius, Karyn ^a   Dong, Krista ^c   Moodley, Amber ^c   Newell, Evan W ^h   Kasprowicz, Victoria ^a   Abdool Karim, Salim S ^k,m   Goulder, Philip ^a,g   Shalek, Alex K ^c,d,e,n   Walker, Bruce D ^a,c,o   Ndung'u, Thumbi ^a,c,p   Leslie, Alasdair ^a,c   more..

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^f KAROLINSKA INSTITUTE   (Sweden)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h AGENCY FOR SCIENCE   (Singapore)

ⁱ Department of Trauma and Critical Care   (South Africa)

^j Stanger Regional Hospital   (South Africa)

^k UNIVERSITY OF KWAZULU NATAL   (South Africa)

^l UNIVERSITY OF CAPE TOWN   (South Africa)

^m Och Spine at New York Presbyterian Hospitals   (United States)

ⁿ HARVARD MEDICAL SCHOOL   (United States)

^o HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^p MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

more..

Author keywords

HIV infection; Innate lymphoid cells

Indexed keywords

ANTIRETROVIRUS AGENT; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 22; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AHR; TRANSCRIPTION FACTOR EOMES; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR HELIOS; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIVIRUS AGENT;

ACUTE PHASE RESPONSE; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELL VIABILITY; CHRONIC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INTESTINE; LYMPHOID CELL; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; TONSIL; UPREGULATION; VIREMIA; ACUTE DISEASE; CELL CULTURE; CELL MOTION; COHORT ANALYSIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; INNATE IMMUNITY; LYMPHOCYTE; METABOLISM; PATHOLOGY; TIME FACTOR; TREATMENT OUTCOME; VIROLOGY; VIRUS LOAD;

ACUTE DISEASE; ANTIVIRAL AGENTS; APOPTOSIS; CELL MOVEMENT; CELLS, CULTURED; CHRONIC DISEASE; COHORT STUDIES; GENE EXPRESSION REGULATION; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, INNATE; INTERFERON-GAMMA; INTESTINES; LYMPHOCYTES; TIME FACTORS; TREATMENT OUTCOME; VIRAL LOAD;

EID: 84958108976     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.01.006     Document Type: Article

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