Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells

Inflammation

Volumn 39, Issue 1, 2016, Pages 473-482

  Kim, Seong Kyu ^a   Choe, Jung Yoon ^a   Park, Ki Yeun ^a  

^a Catholic University of Daegu   (South Korea)

Author keywords

inflammasome; inflammation; interleukin 1 ; rebamipide; uric acid

Indexed keywords

CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE; REBAMIPIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; URATE; VASCULAR CELL ADHESION MOLECULE 1; ALANINE; ASCORBIC ACID; COLCHICINE; DEXAMETHASONE; IL1B PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NLRP3 PROTEIN, HUMAN; QUINOLONE DERIVATIVE; URIC ACID;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENDOTHELIUM CELL; GENE EXPRESSION; GOUT; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ALANINE; ASCORBIC ACID; CASPASE 1; CELL LINE; COLCHICINE; DEXAMETHASONE; ENZYME ACTIVATION; GOUT; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; NAD; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATIVE STRESS; QUINOLONES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; URIC ACID; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84958093766     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-015-0271-5     Document Type: Article

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