Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women

Biomarkers

Volumn 20, Issue 8, 2015, Pages 557-564

  Kluzek, Stefan ^a,b   Bay Jensen, Anne Christine ^c   Judge, Andrew ^a,d   Karsdal, Morten A ^c   Shorthose, Matthew ^b   Spector, Tim ^e   Hart, Deborah ^e   Newton, Julia L ^b   Arden, Nigel K ^a,b,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NORDIC BIOSCIENCE A S   (Denmark)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cohort; COMP; Epidemiology; Knee; Osteoarthritis

Indexed keywords

CARTILAGE OLIGOMERIC MATRIX PROTEIN; BIOLOGICAL MARKER; COMP PROTEIN, HUMAN;

ADULT; ARTICLE; COHORT ANALYSIS; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; KNEE OSTEOARTHRITIS; KNEE PAIN; KNEE RADIOGRAPHY; MAJOR CLINICAL STUDY; MIDDLE AGED; PREDICTIVE VALUE; PROTEIN BLOOD LEVEL; ARTHRALGIA; BLOOD; DIAGNOSTIC IMAGING; DISEASE COURSE; ENGLAND; KNEE; LONGITUDINAL STUDY; METABOLISM; ODDS RATIO; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT; RADIOGRAPHY; RISK FACTOR; STATISTICAL MODEL; TIME FACTOR; UPREGULATION;

ARTHRALGIA; BIOMARKERS; CARTILAGE OLIGOMERIC MATRIX PROTEIN; DISEASE PROGRESSION; ENGLAND; FEMALE; HUMANS; INCIDENCE; KNEE JOINT; LOGISTIC MODELS; LONGITUDINAL STUDIES; MIDDLE AGED; ODDS RATIO; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT; PREDICTIVE VALUE OF TESTS; RADIOGRAPHY; RISK FACTORS; TIME FACTORS; UP-REGULATION;

EID: 84958092946     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2015.1105498     Document Type: Article

References (52)

1. Addison S, Coleman RE, Feng S, et al. (2009). Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation. Arthritis Rheum 60: 3366-73
2. Bartels EM, Christensen R, Christensen P, et al. (2014). Effect of a 16 weeks weight loss program on osteoarthritis biomarkers in obese patients with knee osteoarthritis: a prospective cohort study. Osteoarthritis Cartilage 22: 1817-25
3. Berry PA, Maciewicz RA, Wluka AE, et al. (2010). Relationship of serum markers of cartilage metabolism to imaging and clinical outcome measures of knee joint structure. Ann Rheum Dis 69: 1816-22
4. Blumenfeld O, Williams FM, Hart DJ, et al. (2013). Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study. Osteoarthritis Cartilage 21: 923-9
5. Cibere J, Zhang H, Garnero P, et al. (2009). Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study. Arthritis Rheum 60: 1372-80
6. Cooper C, Arden NK. (2011). Excess mortality in osteoarthritis. BMJ 342: d1407
7. Culliford DJ, Maskell J, Kiran A, et al. (2012). The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database. Osteoarthritis Cartilage 20: 519-24
8. Daghestani HN, Pieper CF, Kraus VB. (2015). Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis. Arthritis Rheumatol 67: 956-65
9. Dahlberg L, Roos H, Saxne T, et al. (1994). Cartilage metabolism in the injured and uninjured knee of the same patient. Ann Rheum Dis 53: 823-7
10. Ene R, Sinescu RD, Ene P, et al. (2015). Synovial inflammation in patients with different stages of knee osteoarthritis. Rom J Morphol Embryol 56: 169-73
11. Fernandes FA, Pucinelli ML, da Silva NP, Feldman D. (2007). Serum cartilage oligomeric matrix protein (COMP) levels in knee osteoarthritis in a Brazilian population: clinical and radiological correlation. Scand J Rheumatol 36: 211-15
12. Fife RS. (1988). Identification of cartilage matrix glycoprotein in synovial fluid in human osteoarthritis. Arthritis Rheum 31: 553-6
13. Fife RS, Brandt KD, Braunstein EM, et al. (1991). The presence of cartilage matrix glycoprotein in serum as determined by immunolocation analysis is not a sensitive indicator of "early" osteoarthritis of the knee. J Lab Clin Med 117: 332-8
14. Guo Y, Bozic D, Malashkevich VN, et al. (1998). All-trans retinol, vitamin D and other hydrophobic compounds bind in the axial pore of the five-stranded coiled-coil domain of cartilage oligomeric matrix protein. EMBO J 17: 5265-72
15. Halász K, Kassner A, Mörgelin M, Heinegard D. (2007). COMP acts as a catalyst in collagen fibrillogenesis. J Biol Chem 282: 31166-73
16. Hart DJ, Spector TD. (1993a). Cigarette smoking and risk of osteoarthritis in women in the general population: the Chingford study. Ann Rheum Dis 52: 93-6
17. Hart DJ, Spector TD. (1993b). The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. J Rheumatol 20: 331-5
18. Hoch JM, Mattacola CG, Medina McKeon JM, et al. (2011). Serum cartilage oligomeric matrix protein (sCOMP) is elevated in patients with knee osteoarthritis: a systematic review and meta-analysis. Osteoarthritis Cartilage 19: 1396-404
19. Hunter DJ, Li J, LaValley M, et al. (2007). Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study. Arthritis Res Ther 9: R108
20. Jordan JM, Luta G, Stabler T, et al. (2003). Ethnic and sex differences in serum levels of cartilage oligomeric matrix protein: the Johnston County Osteoarthritis Project. Arthritis Rheum 48: 675-81
21. Karsdal MA, Bay-Jensen AC, Lories RJ, et al. (2014). The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments? Ann Rheum Dis 73: 336-48.
22. Kellgren JH, Lawrence JS. (1957). Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16: 494-502
23. Kellgren JH, Jeffrey MR, Ball J. (1963). The epidemiology of chronic rheumatism. Volume 2. In: Kellgren JH, Jeffrey MR, Ball J., eds. Atlas of standard radiographs of arthritis. Symposium on population studies in relation to chronic rheumatic diseases. Oxford: Blackwell Scientific Publications, 22-32
24. Kerkhof HJ, Bierma-Zeinstra SM, Arden NK, et al. (2014). Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors. Ann Rheum Dis 73: 2116-21
25. Kim OH, Park H, Seong MW, et al. (2011). Revisit of multiple epiphyseal dysplasia: ethnic difference in genotypes and comparison of radiographic features linked to the COMP and MATN3 genes. Am J Med Genet A 155A: 2669-80
26. Kluzek S, Bay-Jensen AC, Spector T, et al. (2014). Higher serum levels of cartilage oligomeric matrix protein (comp) are associated with self-reported knee pain. Osteoarthritis Cartilage 22: S74
27. Kluzek S, Sanchez-Santos MT, Leyland KM, et al. (2015). Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women. Ann Rheum Dis. [Epub ahead of print]. doi: 10.1136/annrheumdis-2015-208056
28. Kong SY, Stabler TV, Criscione LG, et al. (2006). Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis. Arthritis Rheum 54: 2496-504
29. Lai Y, Yu XP, Zhang Y, et al. (2012). Enhanced COMP catabolism detected in serum of patients with arthritis and animal disease models through a novel capture ELISA. Osteoarthritis Cartilage 20: 854-62
30. Leyland KM, Hart DJ, Javaid MK, et al. (2012). The natural history of radiographic knee osteoarthritis: a fourteen-year population-based cohort study. Arthritis Rheum 64: 2243-51
31. Liu Q, Niu J, Huang J, et al. (2015). Knee osteoarthritis and all-cause mortality: the Wuchuan Osteoarthritis Study. Osteoarthritis Cartilage 23: 1154-7
32. Lohmander LS, Saxne T, Heinegård DK. (1994). Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis. Ann Rheum Dis 53: 8-13
33. Losina E, Weinstein AM, Reichmann WM, et al. (2013). Lifetime risk and age at diagnosis of symptomatic knee osteoarthritis in the US. Arthritis Care Res (Hoboken) 65: 703-11
34. Müller G, Michel A, Altenburg E. (1998). COMP (cartilage oligomeric matrix protein) is synthesized in ligament, tendon, meniscus, and articular cartilage. Connect Tissue Res 39: 233-44
35. Murphy L, Schwartz TA, Helmick CG, et al. (2008). Lifetime risk of symptomatic knee osteoarthritis. Arthritis Rheum 59: 1207-13
36. Neidhart M, Müller-Ladner U, Frey W, et al. (2000). Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners. Osteoarthritis Cartilage 8: 222-9
37. Niehoff A, Kersting UG, Helling S, et al. (2010). Different mechanical loading protocols influence serum cartilage oligomeric matrix protein levels in young healthy humans. Eur J Appl Physiol 110: 651-7
38. Nüesch E, Dieppe P, Reichenbach S, et al. (2011). All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study. BMJ 342: d1165
39. Ozbek S, Engel J, Stetefeld J. (2002). Storage function of cartilage oligomeric matrix protein: the crystal structure of the coiled-coil domain in complex with vitamin D(3). EMBO J 21: 5960-8
40. Peat G, McCarney P, Croft P. (2001). Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis 60: 91-7
41. Saxne T, Heinegård D. (1992). Cartilage oligomeric matrix protein: a novel marker of cartilage turnover detectable in synovial fluid and blood. Br J Rheumatol 31: 583-91
42. Semanik PA, Lee J, Song J, et al. (2015). Accelerometer-monitored sedentary behavior and observed physical function loss. Am J Public Health 105: e1-7
43. Soni A, Kiran A, Hart DJ, et al. (2012). Prevalence of reported knee pain over twelve years in a community-based cohort. Arthritis Rheum 64: 1145-52
44. Sowers MF, Karvonen-Gutierrez CA, Yosef M, et al. (2009). Longitudinal changes of serum COMP and urinary CTX-II predict X-ray defined knee osteoarthritis severity and stiffness in women. Osteoarthritis Cartilage 17: 1609-14
45. Spector TD, Hart DJ, Byrne J, et al. (1993). Definition of osteoarthritis of the knee for epidemiological studies. Ann Rheum Dis 52: 790-4
46. Stoppiello LA, Mapp PI, Wilson D, et al. (2014). Structural associations of symptomatic knee osteoarthritis. Arthritis Rheumatol 66: 3018-27
47. Suri S, Walsh DA. (2012). Osteochondral alterations in osteoarthritis. Bone 51: 204-11
48. Szoeke CE, Cicuttini FM, Guthrie JR, et al. (2006). Factors affecting the prevalence of osteoarthritis in healthy middle-aged women: data from the longitudinal Melbourne Women's Midlife Health Project. Bone 39: 1149-55
49. Valdes AM, Meulenbelt I, Chassaing E, et al. (2014). Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis. Osteoarthritis Cartilage 22: 683-9
50. Verma P, Dalal K. (2013). Serum cartilage oligomeric matrix protein (COMP) in knee osteoarthritis: a novel diagnostic and prognostic biomarker. J Orthop Res 31: 999-1006
51. Vilím V, Vytásek R, Olejárová M, et al. (2001). Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis. Osteoarthritis Cartilage 9: 612-18
52. Zivanović S, Rackov LP, Zivanović A, et al. (2011). Cartilage oligomeric matrix protein-inflammation biomarker in knee osteoarthritis. Bosn J Basic Med Sci 11: 27-32