Serum cartilage oligomeric matrix protein (COMP) in knee osteoarthritis: A novel diagnostic and prognostic biomarker

Journal of Orthopaedic Research

Volumn 31, Issue 7, 2013, Pages 999-1006

  Verma, Priyanka ^a   Dalal, Krishna ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

biomarker; COMP; diagnosis; knee osteoarthritis; prognosis

Indexed keywords

BIOLOGICAL MARKER; CARTILAGE OLIGOMERIC MATRIX PROTEIN; HEMOGLOBIN; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGE DISTRIBUTION; ARTICLE; BODY MASS; CASE CONTROL STUDY; CLINICAL EVALUATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; KNEE OSTEOARTHRITIS; KNEE PAIN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; VISUAL ANALOG SCALE;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DISEASE PROGRESSION; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GLYCOPROTEINS; HUMANS; INTERLEUKIN-1BETA; KNEE JOINT; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PROGNOSIS; SEX FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878174841     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22324     Document Type: Article

References (40)

1. Altman R, Asch E, Bloch D, et al. 1986. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 29: 1039-1049.
2. Ishiguro N, Kojima T., 2003. The biomarker assay for cartilage destruction in rheumatoid arthritis-which molecules can reflect cartilage breakdown in RA ? Clin Calcium 13: 751-754.
3. Pearle AD, Warren RF, Rodeo SA., 2005. Basic science of articular cartilage and osteoarthritis. Clin Sports Med 24: 1-12. (Pubitemid 43073031)
4. Poole AR., 2002. Can serum biomarker assays measure the progression of cartilage degeneration in osteoarthritis ? Arthritis Rheum 46: 2549-2552. (Pubitemid 36118915)
5. Goldring MB., 2000. Osteoarthritis and cartilage: the role of cytokines. Curr Rheumatol Rep 2: 459-465.
6. Towle CA, Hung HH, Bonassar LJ, et al. 1997. Detection of interleukin-1 in the cartilage of patients with osteoarthritis: a possible autocrine/paracrine role in pathogenesis. Osteoarthritis Cartilage 5: 293-300. (Pubitemid 27396022)
7. Goldring SR, Goldring MB., 2004. The role of cytokines in cartilage matrix degeneration in osteoarthritis. Clin Orthop Relat Res 427: S27-S36. (Pubitemid 39362798)
8. Brinckerhoff CE, Matrisian LM., 2002. Matrix metalloproteinases: a tail of a frog that became a prince. Nat Rev Mol Cell Biol 3: 207-214.
9. Goldring MB, Birkhead J, Sandell LJ, et al. 1988. Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest 82: 2026-2037. (Pubitemid 19054951)
10. Richardson DW, Dodge GR., 2000. Effects of interleukin-1beta and tumor necrosis factor-alpha on expression of matrix-related genes by cultured equine articular chondrocytes. Am J Vet Res 61: 624-630.
11. Aigner T, Soeder S, Haag J., 2006. IL-1beta and BMPs-interactive players of cartilage matrix degradation and regeneration. Eur Cell Mater 12: 49-56; discussion 56. (Pubitemid 44898115)
12. Heinegård D, Saxne T., 1991. Molecular markers of processes in cartilage in joint disease. Br J Rheumatol 30: 21-24.
13. Lohmander LS, Lark MW, Dahlberg L, et al. 1992. Cartilage matrix metabolism in osteoarthritis: markers in synovial fluid, serum, and urine. Clin Biochem 25: 167-174.
14. Thonar EJ., 1990. Serum keratan sulfate concentration as a measure of the catabolism of cartilage proteoglycans. Ryumachi 30: 461-468.
15. Song SY, Han YD, Hong SY, et al. 2012. Chip-based cartilage oligomeric matrix protein detection in serum and synovial fluid for osteoarthritis diagnosis. Anal Biochem 420: 139-146.
16. El-Arman MM, El-Fayoumi G, El-Shal E, et al. 2010. Aggrecan and cartilage oligomeric matrix protein in serum and synovial fluid of patients with knee osteoarthritis. Hosp Spec Surg J 6: 171-176.
17. Recklies AD, Baillargeon L, White C., 1998. Regulation of cartilage oligomeric matrix protein synthesis in human synovial cells and articular chondrocytes. Arthritis Rheum 41: 997-1006. (Pubitemid 28265402)
18. Williams FMK, Spector TD., 2008. Biomarkers in osteoarthritis. Arthritis Res Ther 10: 101.
19. Clark AG, Jordan JM, Vilim V, et al. 1999. Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: the Johnston County Osteoarthritis Project. Arthritis Rheum 42: 2356-2364. (Pubitemid 30333416)
20. Mörgelin M, Heinegård D, Engel J, et al. 1992. Electron microscopy of native cartilage oligomeric matrix protein purified from the Swarm rat chondrosarcoma reveals a five-armed structure. J Biol Chem 267: 6137-6141.
21. Hedbom E, Antonsson P, Hjerpe A, et al. 1992. Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage. J Biol Chem 267: 6132-6136.
22. DiCesare PE, Mörgelin M, Carlson CS, et al. 1995. Cartilage oligomeric matrix protein: isolation and characterization from human articular cartilage. J Orthop Res 13: 422-428.
23. Saxne T, Heinegård D., 1992. Cartilage oligomeric matrix protein: a novel marker of cartilage turnover detectable in synovial fluid and blood. Br J Rheumatol 31: 583-591.
24. Forslind K, Eberhardt K, Jonsson A, et al. 1992. Increased serum concentrations of cartilage oligomeric matrix protein. A prognostic marker in early rheumatoid arthritis. Br J Rheumatol 31: 593-598.
25. Månsson B, Carey D, Alini M, et al. 1995. Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. J Clin Invest 95: 1071-1077.
26. Sharif M, Saxne T, Shepstone L, et al. 1995. Relationship between serum cartilage oligomeric matrix protein levels and disease progression in osteoarthritis of the knee joint. Br J Rheumatol 34: 306-310.
27. Petersson IF, Boegård T, Svensson B, et al. 1998. Changes in cartilage and bone metabolism identified by serum markers in early osteoarthritis of the knee joint. Br J Rheumatol 37: 46-50.
28. Kellgren J, Lawrence JS., 1957. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16: 494-502.
29. Rosenberg K, Olsson H, Mörgelin M, et al. 1998. Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen. J Biol Chem 273: 20397-22403.
30. Holden P, Meadows RS, Chapman KL, et al. 2001. Cartilage oligomeric matrix protein interacts with type IX collagen, and disruptions to these interactions identify a pathogenetic mechanism in a bone dysplasia family. J Biol Chem 276: 6046-6055.
31. Halász K, Kassner A, Mörgelin M, et al. 2007. COMP acts as a catalyst in collagen fibrillogenesis. J Biol Chem 282: 31166-31173. (Pubitemid 350044871)
32. Saxne T, Glennås A, Kvien TK, et al. 1993. Release of cartilage macromolecules into the synovial fluid in patients with acute and prolonged phases of reactive arthritis. Arthritis Rheum 36: 20-25. (Pubitemid 23048674)
33. Lohmander LS, Saxne T, Heinegård DK., 1994. Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis. Ann Rheum Dis 53: 8-13. (Pubitemid 24067401)
34. Månsson B, Heinegård D, Saxne T., 2000. Diagnosis of osteoarthritis in relation to molecular processes in cartilage: comment on the article by Clark et al. Arthritis Rheum 43: 1425-1427. (Pubitemid 30416335)
35. Jordan JM, Luta G, Stabler T, et al. 2003. Ethnic and sex differences in serum levels of cartilage oligomeric matrix protein: the Johnston County Osteoarthritis Project. Arthritis Rheum 48: 675-681. (Pubitemid 36302003)
36. Hart DJ, Doyle DV, Spector TD., 1999. Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford study. Arthritis Rheum 42: 17-24. (Pubitemid 29042565)
37. Kobayashi M, Squires GR, Mousa A, et al. 2005. Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage. Arthritis Rheum 52: 128-135. (Pubitemid 40129241)
38. Burrage PS, Mix KS, Brinckerhoff CE., 2006. Matrix metalloproteinases: role in arthritis. Front Biosci 11: 529-543. (Pubitemid 43258162)
39. Joosten LA, Helsen MM, Saxne T, et al. 1999. IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation. J Immunol 163: 5049-5055. (Pubitemid 29501273)
40. Belcher C, Yaqub R, Fawthrop F, et al. 1997. Synovial fluid chondroitin and keratan sulphate epitopes, glycosaminoglycans, and hyaluronan in arthritic and normal knees. Ann Rheum Dis 56: 299-307. (Pubitemid 27278517)