메뉴 건너뛰기




Volumn 39, Issue 1, 2016, Pages 138-147

Anti-Inflammatory Effect of Apigenin on LPS-Induced Pro-Inflammatory Mediators and AP-1 Factors in Human Lung Epithelial Cells

Author keywords

A549; AP 1 factors; apigenin; LPS; pro inflammatory mediators

Indexed keywords

APIGENIN; CYCLOOXYGENASE 2; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUNB; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN;

EID: 84958043879     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-015-0232-z     Document Type: Article
Times cited : (73)

References (44)
  • 1
    • 0036694663 scopus 로고    scopus 로고
    • Regulation of cytokine signaling and inflammation
    • COI: 1:CAS:528:DC%2BD38Xmsl2nsL4%3D
    • Hanada, T., and A. Yoshimura. 2002. Regulation of cytokine signaling and inflammation. Cytokine & Growth Factor Reviews 13(4–5): 413–421.
    • (2002) Cytokine & Growth Factor Reviews , vol.13 , Issue.4-5 , pp. 413-421
    • Hanada, T.1    Yoshimura, A.2
  • 3
    • 0030897625 scopus 로고    scopus 로고
    • Bacterial DNA causes septic shock
    • COI: 1:STN:280:DyaK2s3jvVKktA%3D%3D, PID: 9121548
    • Sparwasser, T., T. Miethke, G. Lipford, K. Borschert, H. Hacker, K. Heeg, et al. 1997. Bacterial DNA causes septic shock. Nature 386(6623): 336–337. doi:10.1038/386336a0.
    • (1997) Nature , vol.386 , Issue.6623 , pp. 336-337
    • Sparwasser, T.1    Miethke, T.2    Lipford, G.3    Borschert, K.4    Hacker, H.5    Heeg, K.6
  • 4
    • 0033016573 scopus 로고    scopus 로고
    • The molecular pathogenesis of endotoxic shock and organ failure
    • COI: 1:CAS:528:DyaK1MXitlOhurc%3D, PID: 10203736
    • Karima, R., S. Matsumoto, H. Higashi, and K. Matsushima. 1999. The molecular pathogenesis of endotoxic shock and organ failure. Molecular Medicine Today 5(3): 123–132. doi:10.1016/S1357-4310(98)01430-0.
    • (1999) Molecular Medicine Today , vol.5 , Issue.3 , pp. 123-132
    • Karima, R.1    Matsumoto, S.2    Higashi, H.3    Matsushima, K.4
  • 7
    • 0032722311 scopus 로고    scopus 로고
    • Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion
    • COI: 1:CAS:528:DyaK1MXns1Gkt7g%3D, PID: 10504298
    • Wang, H.Q., and R.C. Smart. 1999. Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion. Journal of Cell Science 112(Pt 20): 3497–3506.
    • (1999) Journal of Cell Science , vol.112 , pp. 3497-3506
    • Wang, H.Q.1    Smart, R.C.2
  • 9
    • 0023491364 scopus 로고
    • Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
    • COI: 1:CAS:528:DyaL1cXlsVSktg%3D%3D, PID: 3317066
    • Tracey, K.J., Y. Fong, D.G. Hesse, K.R. Manogue, A.T. Lee, G.C. Kuo, et al. 1987. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330(6149): 662–664. doi:10.1038/330662a0.
    • (1987) Nature , vol.330 , Issue.6149 , pp. 662-664
    • Tracey, K.J.1    Fong, Y.2    Hesse, D.G.3    Manogue, K.R.4    Lee, A.T.5    Kuo, G.C.6
  • 11
    • 0029073527 scopus 로고
    • Transcription factors: structure, function, and implication in malignant growth
    • COI: 1:CAS:528:DyaK2MXns1yktLc%3D, PID: 7645977
    • Papavassiliou, A.G. 1995. Transcription factors: structure, function, and implication in malignant growth. Anticancer Research 15(3): 891–894.
    • (1995) Anticancer Research , vol.15 , Issue.3 , pp. 891-894
    • Papavassiliou, A.G.1
  • 12
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • COI: 1:CAS:528:DC%2BD38Xjt1Kgsbg%3D, PID: 11988758
    • Shaulian, E., and M. Karin. 2002. AP-1 as a regulator of cell life and death. Nature Cell Biology 4(5): E131–E136. doi:10.1038/ncb0502-e131.
    • (2002) Nature Cell Biology , vol.4 , Issue.5 , pp. E131-E136
    • Shaulian, E.1    Karin, M.2
  • 13
    • 0035971433 scopus 로고    scopus 로고
    • Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity
    • COI: 1:STN:280:DC%2BD3Mzjt1Oisg%3D%3D, PID: 11402339
    • Chinenov, Y., and T.K. Kerppola. 2001. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20(19): 2438–2452. doi:10.1038/sj.onc.1204385.
    • (2001) Oncogene , vol.20 , Issue.19 , pp. 2438-2452
    • Chinenov, Y.1    Kerppola, T.K.2
  • 15
    • 3643123522 scopus 로고    scopus 로고
    • The flavonoids as potential therapeutic agents
    • Kimball ES, (ed), CRC Press, Boca Raton
    • Middleton, E. 1996. The flavonoids as potential therapeutic agents. In Immunopharmaceuticals, ed. E.S. Kimball, 227–257. Boca Raton: CRC Press.
    • (1996) Immunopharmaceuticals , pp. 227-257
    • Middleton, E.1
  • 16
    • 84879799393 scopus 로고    scopus 로고
    • Effect of estrogen and tamoxifen on the expression pattern of AP-1 factors in MCF-7 cells: role of c-Jun, c-Fos, and Fra-1 in cell cycle regulation
    • COI: 1:CAS:528:DC%2BC3sXmslaisr0%3D, PID: 23625206
    • Babu, R.L., M. Naveen Kumar, R.H. Patil, K.S. Devaraju, G.T. Ramesh, and S.C. Sharma. 2013. Effect of estrogen and tamoxifen on the expression pattern of AP-1 factors in MCF-7 cells: role of c-Jun, c-Fos, and Fra-1 in cell cycle regulation. Molecular and Cellular Biochemistry 380(1–2): 143–151. doi:10.1007/s11010-013-1667-x.
    • (2013) Molecular and Cellular Biochemistry , vol.380 , Issue.1-2 , pp. 143-151
    • Babu, R.L.1    Naveen Kumar, M.2    Patil, R.H.3    Devaraju, K.S.4    Ramesh, G.T.5    Sharma, S.C.6
  • 17
    • 34250836008 scopus 로고    scopus 로고
    • Uranium induces oxidative stress in lung epithelial cells
    • COI: 1:CAS:528:DC%2BD2sXls1Sgs78%3D, PID: 17124605
    • Periyakaruppan, A., F. Kumar, S. Sarkar, C.S. Sharma, and G.T. Ramesh. 2007. Uranium induces oxidative stress in lung epithelial cells. Archives of Toxicology 81(6): 389–395. doi:10.1007/s00204-006-0167-0.
    • (2007) Archives of Toxicology , vol.81 , Issue.6 , pp. 389-395
    • Periyakaruppan, A.1    Kumar, F.2    Sarkar, S.3    Sharma, C.S.4    Ramesh, G.T.5
  • 18
    • 14844354700 scopus 로고
    • Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macrophage cell line RAW 264.7
    • COI: 1:CAS:528:DyaK2MXkvFOrurk%3D
    • Eigler, A., J. Moeller, and S. Endres. 1995. Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macrophage cell line RAW 264.7. Journal of Immunology (Baltimore, Md: 1950) 154(8): 4048–4054.
    • (1995) Journal of Immunology (Baltimore, Md: 1950) , vol.154 , Issue.8 , pp. 4048-4054
    • Eigler, A.1    Moeller, J.2    Endres, S.3
  • 19
    • 0033305448 scopus 로고    scopus 로고
    • Expression and function of estrogen receptor subtypes in granulosa cells: regulation by estradiol and forskolin
    • COI: 1:CAS:528:DyaK1MXlslSqs78%3D, PID: 10465306
    • Sharma, S.C., J.W. Clemens, M.D. Pisarska, and J.S. Richards. 1999. Expression and function of estrogen receptor subtypes in granulosa cells: regulation by estradiol and forskolin. Endocrinology 140(9): 4320–4334. doi:10.1210/endo.140.9.6965.
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 4320-4334
    • Sharma, S.C.1    Clemens, J.W.2    Pisarska, M.D.3    Richards, J.S.4
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • COI: 1:CAS:528:DyaE28XksVehtrY%3D, PID: 942051
    • Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72: 248–254.
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 21
    • 35648941579 scopus 로고    scopus 로고
    • Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals
    • COI: 1:CAS:528:DC%2BD2sXhtlShtb7L, PID: 17893865
    • Murakami, A., and H. Ohigashi. 2007. Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals. International Journal of Cancer Journal International du Cancer 121(11): 2357–2363. doi:10.1002/ijc.23161.
    • (2007) International Journal of Cancer Journal International du Cancer , vol.121 , Issue.11 , pp. 2357-2363
    • Murakami, A.1    Ohigashi, H.2
  • 23
    • 0027494730 scopus 로고
    • Anti-inflammatory actions of steroids: molecular mechanisms
    • COI: 1:CAS:528:DyaK2cXpsF2jtw%3D%3D, PID: 7510080
    • Barnes, P.J., and I. Adcock. 1993. Anti-inflammatory actions of steroids: molecular mechanisms. Trends in Pharmacological Sciences 14(12): 436–441.
    • (1993) Trends in Pharmacological Sciences , vol.14 , Issue.12 , pp. 436-441
    • Barnes, P.J.1    Adcock, I.2
  • 25
    • 0034280608 scopus 로고    scopus 로고
    • Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells
    • COI: 1:CAS:528:DC%2BD3cXnt1art7g%3D, PID: 11055382
    • Iwashita, K., M. Kobori, K. Yamaki, and T. Tsushida. 2000. Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. Bioscience, Biotechnology, and Biochemistry 64(9): 1813–1820. doi:10.1271/bbb.64.1813.
    • (2000) Bioscience, Biotechnology, and Biochemistry , vol.64 , Issue.9 , pp. 1813-1820
    • Iwashita, K.1    Kobori, M.2    Yamaki, K.3    Tsushida, T.4
  • 26
    • 33750720916 scopus 로고    scopus 로고
    • Apigenin suppresses cancer cell growth through ERbeta
    • COI: 1:CAS:528:DC%2BD28Xht1eitrfP, PID: 17132221
    • Mak, P., Y.K. Leung, W.Y. Tang, C. Harwood, and S.M. Ho. 2006. Apigenin suppresses cancer cell growth through ERbeta. Neoplasia 8(11): 896–904. doi:10.1593/neo.06538.
    • (2006) Neoplasia , vol.8 , Issue.11 , pp. 896-904
    • Mak, P.1    Leung, Y.K.2    Tang, W.Y.3    Harwood, C.4    Ho, S.M.5
  • 27
    • 0032831286 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
    • COI: 1:CAS:528:DyaK1MXmslGktb0%3D, PID: 10506109
    • Liang, Y.C., Y.T. Huang, S.H. Tsai, S.Y. Lin-Shiau, C.F. Chen, and J.K. Lin. 1999. Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis 20(10): 1945–1952.
    • (1999) Carcinogenesis , vol.20 , Issue.10 , pp. 1945-1952
    • Liang, Y.C.1    Huang, Y.T.2    Tsai, S.H.3    Lin-Shiau, S.Y.4    Chen, C.F.5    Lin, J.K.6
  • 28
    • 0035846885 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1
    • COI: 1:CAS:528:DC%2BD3MXlvFKrtA%3D%3D, PID: 11213362
    • Raso, G.M., R. Meli, G. Di Carlo, M. Pacilio, and R. Di Carlo. 2001. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1. Life Sciences 68(8): 921–931.
    • (2001) Life Sciences , vol.68 , Issue.8 , pp. 921-931
    • Raso, G.M.1    Meli, R.2    Di Carlo, G.3    Pacilio, M.4    Di Carlo, R.5
  • 29
    • 70349424713 scopus 로고    scopus 로고
    • Anti-inflammatory effects of apigenin on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1
    • COI: 1:CAS:528:DC%2BD1MXht1WmsrnE, PID: 19729077
    • Jeong, G.S., S.H. Lee, S.N. Jeong, Y.C. Kim, and E.C. Kim. 2009. Anti-inflammatory effects of apigenin on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1. International Immunopharmacology 9(12): 1374–1380. doi:10.1016/j.intimp.2009.08.015.
    • (2009) International Immunopharmacology , vol.9 , Issue.12 , pp. 1374-1380
    • Jeong, G.S.1    Lee, S.H.2    Jeong, S.N.3    Kim, Y.C.4    Kim, E.C.5
  • 30
    • 1542544881 scopus 로고    scopus 로고
    • Combinatorial effects of nonsteroidal anti-inflammatory drugs and food constituents on production of prostaglandin E2 and tumor necrosis factor-alpha in RAW264.7 murine macrophages
    • COI: 1:CAS:528:DC%2BD3sXktlygtbg%3D, PID: 12834283
    • Murakami, A., D. Takahashi, K. Hagihara, K. Koshimizu, and H. Ohigashi. 2003. Combinatorial effects of nonsteroidal anti-inflammatory drugs and food constituents on production of prostaglandin E2 and tumor necrosis factor-alpha in RAW264.7 murine macrophages. Bioscience, Biotechnology, and Biochemistry 67(5): 1056–1062.
    • (2003) Bioscience, Biotechnology, and Biochemistry , vol.67 , Issue.5 , pp. 1056-1062
    • Murakami, A.1    Takahashi, D.2    Hagihara, K.3    Koshimizu, K.4    Ohigashi, H.5
  • 31
    • 0032787622 scopus 로고    scopus 로고
    • Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization
    • COI: 1:CAS:528:DyaK1MXks1Sltrw%3D, PID: 10484661
    • Boucher, J.L., C. Moali, and J.P. Tenu. 1999. Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. Cellular and Molecular Life Sciences: CMLS 55(8–9): 1015–1028.
    • (1999) Cellular and Molecular Life Sciences: CMLS , vol.55 , Issue.8-9 , pp. 1015-1028
    • Boucher, J.L.1    Moali, C.2    Tenu, J.P.3
  • 32
    • 84940007173 scopus 로고    scopus 로고
    • Apigenin inhibits PMA-induced expression of pro-inflammatory cytokines and AP-1 factors in A549 cells
    • COI: 1:CAS:528:DC%2BC2MXisFektb0%3D, PID: 25666088
    • Patil, R.H., R.L. Babu, M. Naveen Kumar, K.M. Kiran Kumar, S.M. Hegde, G.T. Ramesh, et al. 2015. Apigenin inhibits PMA-induced expression of pro-inflammatory cytokines and AP-1 factors in A549 cells. Molecular and Cellular Biochemistry 403(1–2): 95–106. doi:10.1007/s11010-015-2340-3.
    • (2015) Molecular and Cellular Biochemistry , vol.403 , Issue.1-2 , pp. 95-106
    • Patil, R.H.1    Babu, R.L.2    Naveen Kumar, M.3    Kiran Kumar, K.M.4    Hegde, S.M.5    Ramesh, G.T.6
  • 33
    • 34447532263 scopus 로고    scopus 로고
    • Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B
    • COI: 1:CAS:528:DC%2BD2sXnt1CmtL4%3D, PID: 17234720
    • Chung, W.Y., J.H. Park, M.J. Kim, H.O. Kim, J.K. Hwang, S.K. Lee, et al. 2007. Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B. Carcinogenesis 28(6): 1224–1231. doi:10.1093/carcin/bgm005.
    • (2007) Carcinogenesis , vol.28 , Issue.6 , pp. 1224-1231
    • Chung, W.Y.1    Park, J.H.2    Kim, M.J.3    Kim, H.O.4    Hwang, J.K.5    Lee, S.K.6
  • 34
    • 9644289387 scopus 로고    scopus 로고
    • Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?
    • COI: 1:CAS:528:DC%2BD2MXhs1Ohug%3D%3D, PID: 15546398
    • Andreakos, E., B. Foxwell, and M. Feldmann. 2004. Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation? Immunological Reviews 202: 250–265. doi:10.1111/j.0105-2896.2004.00202.x.
    • (2004) Immunological Reviews , vol.202 , pp. 250-265
    • Andreakos, E.1    Foxwell, B.2    Feldmann, M.3
  • 35
    • 33645985490 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitory natural products: current status
    • COI: 1:CAS:528:DC%2BD28XisVWjsLY%3D, PID: 16529558
    • Jachak, S.M. 2006. Cyclooxygenase inhibitory natural products: current status. Current Medicinal Chemistry 13(6): 659–678.
    • (2006) Current Medicinal Chemistry , vol.13 , Issue.6 , pp. 659-678
    • Jachak, S.M.1
  • 36
    • 4444263810 scopus 로고    scopus 로고
    • Molecular therapeutic targets in inflammation: cyclooxygenase and NF-kappaB
    • COI: 1:CAS:528:DC%2BD2cXmvVemur0%3D, PID: 15379601
    • Krakauer, T. 2004. Molecular therapeutic targets in inflammation: cyclooxygenase and NF-kappaB. Current Drug Targets. Inflammation and Allergy 3(3): 317–324.
    • (2004) Current Drug Targets. Inflammation and Allergy , vol.3 , Issue.3 , pp. 317-324
    • Krakauer, T.1
  • 37
    • 77649231980 scopus 로고    scopus 로고
    • Evaluation of inhibitory activities of plant extracts on production of LPS-stimulated pro-inflammatory mediators in J774 murine macrophages
    • COI: 1:CAS:528:DC%2BC3cXitlKitrg%3D, PID: 19813079
    • Verma, N., S.K. Tripathi, D. Sahu, H.R. Das, and R.H. Das. 2010. Evaluation of inhibitory activities of plant extracts on production of LPS-stimulated pro-inflammatory mediators in J774 murine macrophages. Molecular and Cellular Biochemistry 336(1–2): 127–135. doi:10.1007/s11010-009-0263-6.
    • (2010) Molecular and Cellular Biochemistry , vol.336 , Issue.1-2 , pp. 127-135
    • Verma, N.1    Tripathi, S.K.2    Sahu, D.3    Das, H.R.4    Das, R.H.5
  • 38
    • 0028275028 scopus 로고
    • Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation
    • COI: 1:STN:280:DyaK2c3jsVaqsg%3D%3D, PID: 8178948
    • Mazzucchelli, L., C. Hauser, K. Zgraggen, H. Wagner, M. Hess, J.A. Laissue, et al. 1994. Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. The American Journal of Pathology 144(5): 997–1007.
    • (1994) The American Journal of Pathology , vol.144 , Issue.5 , pp. 997-1007
    • Mazzucchelli, L.1    Hauser, C.2    Zgraggen, K.3    Wagner, H.4    Hess, M.5    Laissue, J.A.6
  • 39
    • 0028218474 scopus 로고
    • Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis
    • COI: 1:CAS:528:DyaK2cXitFeqsrk%3D, PID: 7510036
    • Ohshima, H., and H. Bartsch. 1994. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutation Research 305(2): 253–264.
    • (1994) Mutation Research , vol.305 , Issue.2 , pp. 253-264
    • Ohshima, H.1    Bartsch, H.2
  • 41
    • 0028967819 scopus 로고
    • Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B
    • COI: 1:STN:280:DyaK2M3lsl2msg%3D%3D, PID: 7739549
    • Arenzana-Seisdedos, F., J. Thompson, M.S. Rodriguez, F. Bachelerie, D. Thomas, and R.T. Hay. 1995. Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Molecular and Cellular Biology 15(5): 2689–2696.
    • (1995) Molecular and Cellular Biology , vol.15 , Issue.5 , pp. 2689-2696
    • Arenzana-Seisdedos, F.1    Thompson, J.2    Rodriguez, M.S.3    Bachelerie, F.4    Thomas, D.5    Hay, R.T.6
  • 42
    • 29144435210 scopus 로고    scopus 로고
    • Molecular targets of dietary polyphenols with anti-inflammatory properties
    • COI: 1:CAS:528:DC%2BD2MXhtlSrtLnN, PID: 16259055
    • Yoon, J.H., and S.J. Baek. 2005. Molecular targets of dietary polyphenols with anti-inflammatory properties. Yonsei Medical Journal 46(5): 585–596.
    • (2005) Yonsei Medical Journal , vol.46 , Issue.5 , pp. 585-596
    • Yoon, J.H.1    Baek, S.J.2
  • 43
    • 0344687483 scopus 로고    scopus 로고
    • Substance P induces TNF-alpha and IL-6 production through NF kappa B in peritoneal mast cells
    • COI: 1:CAS:528:DC%2BD3sXptlOqtb0%3D, PID: 14654230
    • Azzolina, A., A. Bongiovanni, and N. Lampiasi. 2003. Substance P induces TNF-alpha and IL-6 production through NF kappa B in peritoneal mast cells. Biochimica et Biophysica Acta 1643(1–3): 75–83.
    • (2003) Biochimica et Biophysica Acta , vol.1643 , Issue.1-3 , pp. 75-83
    • Azzolina, A.1    Bongiovanni, A.2    Lampiasi, N.3
  • 44
    • 0031900740 scopus 로고    scopus 로고
    • Signal transduction through MAP kinase cascades
    • COI: 1:CAS:528:DyaK1cXivVSls70%3D, PID: 9561267
    • Lewis, T.S., P.S. Shapiro, and N.G. Ahn. 1998. Signal transduction through MAP kinase cascades. Advances in Cancer Research 74: 49–139.
    • (1998) Advances in Cancer Research , vol.74 , pp. 49-139
    • Lewis, T.S.1    Shapiro, P.S.2    Ahn, N.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.