-
1
-
-
67651238466
-
Sexual differences in the control of energy homeostasis
-
Shi H, Seeley RJ, Clegg DJ. Sexual differences in the control of energy homeostasis. Front Neuroendocrinol 2009; 30: 396-404.
-
(2009)
Front Neuroendocrinol
, vol.30
, pp. 396-404
-
-
Shi, H.1
Seeley, R.J.2
Clegg, D.J.3
-
2
-
-
84862749395
-
Sex differences in lipid metabolism and metabolic disease risk
-
Sugiyama MG, Agellon LB. Sex differences in lipid metabolism and metabolic disease risk. BiochemCell Biol 2012; 90: 124-141.
-
(2012)
BiochemCell Biol
, vol.90
, pp. 124-141
-
-
Sugiyama, M.G.1
Agellon, L.B.2
-
3
-
-
30544433479
-
Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S
-
Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S. Diabetes Care 2005; 28: 2745-2749.
-
(2005)
Diabetes Care
, vol.28
, pp. 2745-2749
-
-
Ford, E.S.1
-
4
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG. Obesity as a medical problem. Nature 2000; 404: 635-643.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
5
-
-
0033749264
-
Increased adipose tissue in male and female estrogen receptor-alpha knockout mice
-
Heine PA, Taylor JA, Iwamoto GA, Lubahn DB, Cooke PS. Increased adipose tissue in male and female estrogen receptor-alpha knockout mice. Proc Natl Acad Sci USA 2000; 97: 12729-12734.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12729-12734
-
-
Heine, P.A.1
Taylor, J.A.2
Iwamoto, G.A.3
Lubahn, D.B.4
Cooke, P.S.5
-
6
-
-
0028143234
-
Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
-
Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 1994; 331: 1056-1061.
-
(1994)
N Engl J Med
, vol.331
, pp. 1056-1061
-
-
Smith, E.P.1
Boyd, J.2
Frank, G.R.3
Takahashi, H.4
Cohen, R.M.5
Specker, B.6
-
7
-
-
80053899725
-
Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction
-
Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE et al. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab 2011; 14: 453-465.
-
(2011)
Cell Metab
, vol.14
, pp. 453-465
-
-
Xu, Y.1
Nedungadi, T.P.2
Zhu, L.3
Sobhani, N.4
Irani, B.G.5
Davis, K.E.6
-
8
-
-
33847793319
-
Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
-
Musatov S, Chen W, Pfaff DW, Mobbs CV, Yang XJ, Clegg DJ et al. Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proc Natl Acad Sci USA 2007; 104: 2501-2506.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2501-2506
-
-
Musatov, S.1
Chen, W.2
Pfaff, D.W.3
Mobbs, C.V.4
Yang, X.J.5
Clegg, D.J.6
-
9
-
-
64249156962
-
Diet-induced metabolic disturbances as modulators of brain homeostasis
-
Zhang L, Bruce-Keller AJ, Dasuri K, Nguyen AT, Liu Y, Keller JN. Diet-induced metabolic disturbances as modulators of brain homeostasis. Biochim Biophys Acta 2009; 1792: 417-422.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 417-422
-
-
Zhang, L.1
Bruce-Keller, A.J.2
Dasuri, K.3
Nguyen, A.T.4
Liu, Y.5
Keller, J.N.6
-
10
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
11
-
-
84855459760
-
Obesity is associated with hypothalamic injury in rodents and humans
-
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO et al. Obesity is associated with hypothalamic injury in rodents and humans. J Clin Invest 2011; 122: 153-162.
-
(2011)
J Clin Invest
, vol.122
, pp. 153-162
-
-
Thaler, J.P.1
Yi, C.X.2
Schur, E.A.3
Guyenet, S.J.4
Hwang, B.H.5
Dietrich, M.O.6
-
12
-
-
84901496600
-
Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus
-
Zhang QG, Wang R, Tang H, Dong Y, Chan A, Sareddy GR et al. Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus. Mol Cell Endocrinol 2014; 389: 84-91.
-
(2014)
Mol Cell Endocrinol
, vol.389
, pp. 84-91
-
-
Zhang, Q.G.1
Wang, R.2
Tang, H.3
Dong, Y.4
Chan, A.5
Sareddy, G.R.6
-
13
-
-
84874199652
-
17beta-Oestradiol anti-inflammatory effects in primary astrocytes require oestrogen receptor beta-mediated neuroglobin up-regulation
-
De Marinis E, Acaz-Fonseca E, Arevalo MA, Ascenzi P, Fiocchetti M, Marino M et al. 17beta-Oestradiol anti-inflammatory effects in primary astrocytes require oestrogen receptor beta-mediated neuroglobin up-regulation. J Neuroendocrinol 2013; 25: 260-270.
-
(2013)
J Neuroendocrinol
, vol.25
, pp. 260-270
-
-
De Marinis, E.1
Acaz-Fonseca, E.2
Arevalo, M.A.3
Ascenzi, P.4
Fiocchetti, M.5
Marino, M.6
-
14
-
-
84916929057
-
17beta-estradiol and inflammation: Implications for ischemic stroke
-
Petrone AB, Simpkins JW, Barr TL. 17beta-estradiol and inflammation: implications for ischemic stroke. Aging Dis 2014; 5: 340-345.
-
(2014)
Aging Dis
, vol.5
, pp. 340-345
-
-
Petrone, A.B.1
Simpkins, J.W.2
Barr, T.L.3
-
15
-
-
84919674550
-
Hypothalamic PGC-1alpha protects against high-fat diet exposure by regulating ERalpha
-
Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C et al. Hypothalamic PGC-1alpha protects against high-fat diet exposure by regulating ERalpha. Cell Rep 2014; 9: 633-645.
-
(2014)
Cell Rep
, vol.9
, pp. 633-645
-
-
Morselli, E.1
Fuente-Martin, E.2
Finan, B.3
Kim, M.4
Frank, A.5
Garcia-Caceres, C.6
-
16
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
Summers SA. Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 2006; 45: 42-72.
-
(2006)
Prog Lipid Res
, vol.45
, pp. 42-72
-
-
Summers, S.A.1
-
17
-
-
84877272187
-
An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice
-
Holland WL, Adams AC, Brozinick JT, Bui HH, Miyauchi Y, Kusminski CM et al. An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice. Cell Metab 2013; 17: 790-797.
-
(2013)
Cell Metab
, vol.17
, pp. 790-797
-
-
Holland, W.L.1
Adams, A.C.2
Brozinick, J.T.3
Bui, H.H.4
Miyauchi, Y.5
Kusminski, C.M.6
-
18
-
-
63249117466
-
Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance
-
Haus JM, Kashyap SR, Kasumov T, Zhang R, Kelly KR, Defronzo RA et al. Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance. Diabetes 2009; 58: 337-343.
-
(2009)
Diabetes
, vol.58
, pp. 337-343
-
-
Haus, J.M.1
Kashyap, S.R.2
Kasumov, T.3
Zhang, R.4
Kelly, K.R.5
Defronzo, R.A.6
-
19
-
-
84865578156
-
Consumption of a high-fat diet, but not regular endurance exercise training, regulates hypothalamic lipid accumulation in mice
-
Borg ML, Omran SF, Weir J, Meikle PJ, Watt MJ. Consumption of a high-fat diet, but not regular endurance exercise training, regulates hypothalamic lipid accumulation in mice. J Physiol 2012; 590: 4377-4389.
-
(2012)
J Physiol
, vol.590
, pp. 4377-4389
-
-
Borg, M.L.1
Omran, S.F.2
Weir, J.3
Meikle, P.J.4
Watt, M.J.5
-
20
-
-
79955487247
-
Lipidinduced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
-
Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S et al. Lipidinduced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest 2011; 121: 1858-1870.
-
(2011)
J Clin Invest
, vol.121
, pp. 1858-1870
-
-
Holland, W.L.1
Bikman, B.T.2
Wang, L.P.3
Yuguang, G.4
Sargent, K.M.5
Bulchand, S.6
-
21
-
-
67349130083
-
Glycosphingolipids and insulin resistance
-
Langeveld M, Aerts JM. Glycosphingolipids and insulin resistance. Prog Lipid Res 2009; 48: 196-205.
-
(2009)
Prog Lipid Res
, vol.48
, pp. 196-205
-
-
Langeveld, M.1
Aerts, J.M.2
-
22
-
-
33750590489
-
Altered adipose and plasma sphingolipid metabolism in obesity: A potential mechanism for cardiovascular and metabolic risk
-
Samad F, Hester KD, Yang G, Hannun YA, Bielawski J. Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk. Diabetes 2006; 55: 2579-2587.
-
(2006)
Diabetes
, vol.55
, pp. 2579-2587
-
-
Samad, F.1
Hester, K.D.2
Yang, G.3
Hannun, Y.A.4
Bielawski, J.5
-
23
-
-
84883240503
-
The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis
-
Davis KE, D Neinast M, Sun K, M Skiles W, D Bills J, A Zehr J et al. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Mol Metab 2013; 2: 227-242.
-
(2013)
Mol Metab
, vol.2
, pp. 227-242
-
-
Davis, K.E.1
Neinast M, D.2
Sun, K.3
Skiles W, M.4
Bills J, D.5
Zehr J, A.6
-
24
-
-
66149118129
-
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
-
Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A et al. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 2009; 296: E1003-E1012.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, pp. E1003-E1012
-
-
Posey, K.A.1
Clegg, D.J.2
Printz, R.L.3
Byun, J.4
Morton, G.J.5
Vivekanandan-Giri, A.6
-
25
-
-
0000803875
-
Plasma free fatty acid concentrations in obesity
-
Opie LH, Walfish PG. Plasma free fatty acid concentrations in obesity. N Engl J Med 1963; 268: 757-760.
-
(1963)
N Engl J Med
, vol.268
, pp. 757-760
-
-
Opie, L.H.1
Walfish, P.G.2
-
26
-
-
0041922555
-
Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol
-
Vegeto E, Belcredito S, Etteri S, Ghisletti S, Brusadelli A, Meda C et al. Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol. Proc Natl Acad Sci USA 2003; 100: 9614-9619.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9614-9619
-
-
Vegeto, E.1
Belcredito, S.2
Etteri, S.3
Ghisletti, S.4
Brusadelli, A.5
Meda, C.6
-
27
-
-
84879315379
-
Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERalpha signaling on astrocytes but not through ERbeta signaling on astrocytes or neurons
-
Spence RD, Wisdom AJ, Cao Y, Hill HM, Mongerson CR, Stapornkul B et al. Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERalpha signaling on astrocytes but not through ERbeta signaling on astrocytes or neurons. J Neurosci 2013; 33: 10924-10933.
-
(2013)
J Neurosci
, vol.33
, pp. 10924-10933
-
-
Spence, R.D.1
Wisdom, A.J.2
Cao, Y.3
Hill, H.M.4
Mongerson, C.R.5
Stapornkul, B.6
-
28
-
-
15244348980
-
The nuclear receptor coactivator PGC-1alpha exhibits modes of interaction with the estrogen receptor distinct from those of SRC-1
-
Bourdoncle A, Labesse G, Margueron R, Castet A, Cavailles V, Royer CA. The nuclear receptor coactivator PGC-1alpha exhibits modes of interaction with the estrogen receptor distinct from those of SRC-1. J Mol Biol 2005; 347: 921-934.
-
(2005)
J Mol Biol
, vol.347
, pp. 921-934
-
-
Bourdoncle, A.1
Labesse, G.2
Margueron, R.3
Castet, A.4
Cavailles, V.5
Royer, C.A.6
-
29
-
-
0034717075
-
Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1
-
Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP. Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. J Biol Chem 2000; 275: 16302-16308.
-
(2000)
J Biol Chem
, vol.275
, pp. 16302-16308
-
-
Tcherepanova, I.1
Puigserver, P.2
Norris, J.D.3
Spiegelman, B.M.4
McDonnell, D.P.5
-
30
-
-
84922479473
-
Polyunsaturated fatty acids and their metabolites in brain function and disease
-
Bazinet RP, Laye S. Polyunsaturated fatty acids and their metabolites in brain function and disease. Nat Rev Neurosci 2014; 15: 771-785.
-
(2014)
Nat Rev Neurosci
, vol.15
, pp. 771-785
-
-
Bazinet, R.P.1
Laye, S.2
-
31
-
-
84866431447
-
Cognitive enhancement by omega-3 fatty acids from child-hood to old age: Findings from animal and clinical studies
-
Luchtman DW, Song C. Cognitive enhancement by omega-3 fatty acids from child-hood to old age: findings from animal and clinical studies. Neuropharmacology 2013; 64: 550-565.
-
(2013)
Neuropharmacology
, vol.64
, pp. 550-565
-
-
Luchtman, D.W.1
Song, C.2
-
32
-
-
0034500422
-
Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment
-
Conquer JA, Tierney MC, Zecevic J, Bettger WJ, Fisher RH. Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment. Lipids 2000; 35: 1305-1312.
-
(2000)
Lipids
, vol.35
, pp. 1305-1312
-
-
Conquer, J.A.1
Tierney, M.C.2
Zecevic, J.3
Bettger, W.J.4
Fisher, R.H.5
-
33
-
-
0038115068
-
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease
-
Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 2003; 60: 940-946.
-
(2003)
Arch Neurol
, vol.60
, pp. 940-946
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
Tangney, C.C.4
Bennett, D.A.5
Wilson, R.S.6
-
34
-
-
33750982113
-
Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: The Framingham Heart Study
-
Schaefer EJ, Bongard V, Beiser AS, Lamon-Fava S, Robins SJ, Au R et al. Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch Neurol 2006; 63: 1545-1550.
-
(2006)
Arch Neurol
, vol.63
, pp. 1545-1550
-
-
Schaefer, E.J.1
Bongard, V.2
Beiser, A.S.3
Lamon-Fava, S.4
Robins, S.J.5
Au, R.6
-
35
-
-
34247532861
-
Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults
-
Kiecolt-Glaser JK, Belury MA, Porter K, Beversdorf DQ, Lemeshow S, Glaser R. Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults. Psychosom Med 2007; 69: 217-224.
-
(2007)
Psychosom Med
, vol.69
, pp. 217-224
-
-
Kiecolt-Glaser, J.K.1
Belury, M.A.2
Porter, K.3
Beversdorf, D.Q.4
Lemeshow, S.5
Glaser, R.6
|