High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells

Genes and Development

Volumn 29, Issue 23, 2015, Pages 2420-2434

  Pech, Matthew F ^a   Garbuzov, Alina ^a,b   Hasegawa, Kazuteru ^a   Sukhwani, Meena ^c,d   Zhang, Ruixuan J ^a   Benayoun, Bérénice A ^b   Brockman, Stephanie A ^a   Lin, Shengda ^a   Brunet, Anne ^b   Orwig, Kyle E ^c,d   Artandi, Steven E ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Aging; Germline stem cells; Spermatogenesis; Telomerase; Telomeres

Indexed keywords

TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TERT PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL CYCLE; CELL LOSS; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; GERM CELL; GERMLINE STEM CELL; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; SOMATIC CELL; SPERMATOGONIUM; TELOMERE SHORTENING; TRANSCRIPTOMICS; UNDIFFERENTIATED SPERMATOGONIUM; ADULT STEM CELL; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; ENZYMOLOGY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; METABOLISM; PROMOTER REGION;

ADULT STEM CELLS; ANIMALS; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCK-IN TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; PROMOTER REGIONS, GENETIC; SPERMATOGONIA; TELOMERASE;

EID: 84957803881     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.271783.115     Document Type: Article

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